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The map label for this gene is atpB

Identifier: 78357742

GI number: 78357742

Start: 2703770

End: 2704471

Strand: Direct

Name: atpB

Synonym: Dde_2700

Alternate gene names: 78357742

Gene position: 2703770-2704471 (Clockwise)

Preceding gene: 78357741

Following gene: 78357743

Centisome position: 72.48

GC content: 52.99

Gene sequence:

>702_bases
ATGGCAAGTGGGCTGCCGCATCCGGTACTCCTCAGTGATCTGGTCGGACTGGGTCACATCAATGTCGGCGGACAATCCGT
CGAATTCAAGCACGTTTTTTACACATGGTGTGTCATGGCGATGCTGTTCGCGGTTTCATTCATTGTCCGCGGCAAAATCA
AAATGGTTCCCGGAAAACTGCAGAACATCTTCGAAGTCATCATCGGAGGACTTGAAGAGTTTGTAGTTTCCATCACGGGC
GAAGACGGACGCAAGGTTTACCCTGTCCTCATCGTCTTTTTCCTTTTCATTCTCTGCATGAACCTGACCGGTCTTGTGCC
CGGCTTTGACGCGCCGACCGCGAACATCAACACCACCGCTTCGCTGGCGCTGTTCTGCTTTATCTACTACAACTACATCG
GCATCCAACGCTGGGGCGCCGGTTACATCAAACACTTCATGGGACCCATGTGGTGGCTTTCGCCCCTCATGCTGCCGCTG
GAACTTATCAGCCACACCGCCCGTCCGCTTTCGCTCTCTCTGCGTCTGTTCGGTAACATCCGCGGTGAAGAATTCGTGCT
GATTCTGTTCTTCATGCTGGCACCCATCATCGGCACAATTCCGATCTACTTCCTGTTCACTCTGGCCAAGGTACTGCAGG
CGTTCATCTTCTTCATGCTCGCCACCATCTACCTTAAAGGCTCTCTGGAACACGCCCACTAA

Upstream 100 bases:

>100_bases
CCCTTTGTGTTGATCGCAGGTTTTTCAACCGTTGTGGCGACCACACTGGTCTGGGGTCTTTCCAGACTGGCCGGGCATAA
AGTCAAGGAGGCATGAGGGA

Downstream 100 bases:

>100_bases
TGGGGGAAATGGTCTTAGACCAACAACATAACCTAACTTACACGTAGGAAGGAGTTATCATGCGCAAGTTTCTGATGATC
GCCCTGAACACCCTGGCTAT

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MASGLPHPVLLSDLVGLGHINVGGQSVEFKHVFYTWCVMAMLFAVSFIVRGKIKMVPGKLQNIFEVIIGGLEEFVVSITG
EDGRKVYPVLIVFFLFILCMNLTGLVPGFDAPTANINTTASLALFCFIYYNYIGIQRWGAGYIKHFMGPMWWLSPLMLPL
ELISHTARPLSLSLRLFGNIRGEEFVLILFFMLAPIIGTIPIYFLFTLAKVLQAFIFFMLATIYLKGSLEHAH

Sequences:

>Translated_233_residues
MASGLPHPVLLSDLVGLGHINVGGQSVEFKHVFYTWCVMAMLFAVSFIVRGKIKMVPGKLQNIFEVIIGGLEEFVVSITG
EDGRKVYPVLIVFFLFILCMNLTGLVPGFDAPTANINTTASLALFCFIYYNYIGIQRWGAGYIKHFMGPMWWLSPLMLPL
ELISHTARPLSLSLRLFGNIRGEEFVLILFFMLAPIIGTIPIYFLFTLAKVLQAFIFFMLATIYLKGSLEHAH
>Mature_232_residues
ASGLPHPVLLSDLVGLGHINVGGQSVEFKHVFYTWCVMAMLFAVSFIVRGKIKMVPGKLQNIFEVIIGGLEEFVVSITGE
DGRKVYPVLIVFFLFILCMNLTGLVPGFDAPTANINTTASLALFCFIYYNYIGIQRWGAGYIKHFMGPMWWLSPLMLPLE
LISHTARPLSLSLRLFGNIRGEEFVLILFFMLAPIIGTIPIYFLFTLAKVLQAFIFFMLATIYLKGSLEHAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=209, Percent_Identity=32.0574162679426, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_DESDG (Q30XV0)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389191.1
- ProteinModelPortal:   Q30XV0
- SMR:   Q30XV0
- STRING:   Q30XV0
- GeneID:   3757723
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2700
- NMPDR:   fig|207559.3.peg.3056
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   YIFTILT
- ProtClustDB:   CLSK704937
- BioCyc:   DDES207559:DDE_2700-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 26118; Mature: 25987

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x135b2cf4)-; HASH(0x13c12afc)-; HASH(0x12cdd938)-; HASH(0x13c15204)-; HASH(0x13c1020c)-; HASH(0x13c12ca0)-; HASH(0x139fed0c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGLPHPVLLSDLVGLGHINVGGQSVEFKHVFYTWCVMAMLFAVSFIVRGKIKMVPGKL
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHH
QNIFEVIIGGLEEFVVSITGEDGRKVYPVLIVFFLFILCMNLTGLVPGFDAPTANINTTA
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
SLALFCFIYYNYIGIQRWGAGYIKHFMGPMWWLSPLMLPLELISHTARPLSLSLRLFGNI
HHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RGEEFVLILFFMLAPIIGTIPIYFLFTLAKVLQAFIFFMLATIYLKGSLEHAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
ASGLPHPVLLSDLVGLGHINVGGQSVEFKHVFYTWCVMAMLFAVSFIVRGKIKMVPGKL
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHH
QNIFEVIIGGLEEFVVSITGEDGRKVYPVLIVFFLFILCMNLTGLVPGFDAPTANINTTA
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
SLALFCFIYYNYIGIQRWGAGYIKHFMGPMWWLSPLMLPLELISHTARPLSLSLRLFGNI
HHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RGEEFVLILFFMLAPIIGTIPIYFLFTLAKVLQAFIFFMLATIYLKGSLEHAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA