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The map label for this gene is fur [H]

Identifier: 78357718

GI number: 78357718

Start: 2685553

End: 2685999

Strand: Reverse

Name: fur [H]

Synonym: Dde_2676

Alternate gene names: 78357718

Gene position: 2685999-2685553 (Counterclockwise)

Preceding gene: 78357719

Following gene: 78357717

Centisome position: 72.01

GC content: 53.69

Gene sequence:

>447_bases
ATGAAAGATCCGTTACAGGTATTCACGGATTACATCGTTGCCAACGGCCTGAAAATGACCCCGCAACGGATGTTGATTGT
GGATGTGTTTCTGCGGGAGGATGGCCACCTTACCACCGAGGAGTTGTACGAGAAGGTCAAGCGTGAAGACCCTTCCGTGG
GACAGGCCACTGTGTACCGCACCATGAAGCTGCTCAGCGAATCGGGCATAGCCAAGGAAGTCCGCTTCGGCGACGGGGTG
GCCCGGTATGAGCAGAAGTACGGCAGCAAGCACCATGACCATCTTATCTGCGAAACCTGCGGCAGAAATATCGAGGTGCT
GGACGAGCACATTGAGCTGCTTCAGGAAGAGCTGGCCGCGAAACACGGCTTTGTGCTGACCAGCCACAGGATGTACCTGT
ACGGTGAGTGCAGAGAATGCCGTGACAAAAAAAAGAAGAAATCATAA

Upstream 100 bases:

>100_bases
CGGAACGGCTGGGCAGTGAAGAGCATTATGTAATCCGCAAGGTTGCGTATTGTCAGTCTTGCGGATACTGTCCGGTCATA
CAGAGCCTCTGGAGTCGCCT

Downstream 100 bases:

>100_bases
CGCCGCCCTGCGGGGCGCCGCGTGCCGTATAGCAGGGCGGGCCGGTTACCGGTCCGCCCTTTTGCACGGTACGCGGGCAG
CTGAAAGGACAGGTATATAT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKDPLQVFTDYIVANGLKMTPQRMLIVDVFLREDGHLTTEELYEKVKREDPSVGQATVYRTMKLLSESGIAKEVRFGDGV
ARYEQKYGSKHHDHLICETCGRNIEVLDEHIELLQEELAAKHGFVLTSHRMYLYGECRECRDKKKKKS

Sequences:

>Translated_148_residues
MKDPLQVFTDYIVANGLKMTPQRMLIVDVFLREDGHLTTEELYEKVKREDPSVGQATVYRTMKLLSESGIAKEVRFGDGV
ARYEQKYGSKHHDHLICETCGRNIEVLDEHIELLQEELAAKHGFVLTSHRMYLYGECRECRDKKKKKS
>Mature_148_residues
MKDPLQVFTDYIVANGLKMTPQRMLIVDVFLREDGHLTTEELYEKVKREDPSVGQATVYRTMKLLSESGIAKEVRFGDGV
ARYEQKYGSKHHDHLICETCGRNIEVLDEHIELLQEELAAKHGFVLTSHRMYLYGECRECRDKKKKKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=42.3076923076923, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17191; Mature: 17191

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDPLQVFTDYIVANGLKMTPQRMLIVDVFLREDGHLTTEELYEKVKREDPSVGQATVYR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHH
TMKLLSESGIAKEVRFGDGVARYEQKYGSKHHDHLICETCGRNIEVLDEHIELLQEELAA
HHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
KHGFVLTSHRMYLYGECRECRDKKKKKS
HCCEEEECCCEEEEECHHHHHHHHHCCC
>Mature Secondary Structure
MKDPLQVFTDYIVANGLKMTPQRMLIVDVFLREDGHLTTEELYEKVKREDPSVGQATVYR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHH
TMKLLSESGIAKEVRFGDGVARYEQKYGSKHHDHLICETCGRNIEVLDEHIELLQEELAA
HHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
KHGFVLTSHRMYLYGECRECRDKKKKKS
HCCEEEECCCEEEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]