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The map label for this gene is nreC [H]

Identifier: 78357716

GI number: 78357716

Start: 2684404

End: 2685051

Strand: Direct

Name: nreC [H]

Synonym: Dde_2674

Alternate gene names: 78357716

Gene position: 2684404-2685051 (Clockwise)

Preceding gene: 78357713

Following gene: 78357726

Centisome position: 71.96

GC content: 57.25

Gene sequence:

>648_bases
ATGCCGAAAACAGTTGTCATTGTAGAGGACATGGGCATTGTCCGCGAAGGGGTGCGTGCGCTGTTGGGCGGCTGCCCCGG
GTACCGTATTGCCGGAGAAGCCTCTGACGGCATAGAGGCCCTGCAGGTCGTGGAGCGGTGCGCTCCGGACGTGGTGCTGA
TGGATATAGGCATGCCGCGCATGGACGGTGCAGACGCCATACGCGAAATCAAGCGCCGTTTTCCCCGCACAAAAGTCATA
GCCCTGACCGCGCATAACAAAAGCGCGCTCATTTTCCGCACGCTTCATGCCGGGGCAGACGGATACATGCTGAAAACCGG
CAACTGTGAAACTCTGGTCGGCGCCATACAGACGGTGCTTGAGGGACGGCGGTATATCAGCCCCGACATTTCCCAGTCGC
TCATCGACTCGTTAGCGGGTTCAGACCCCATGGATTTCGCCAATCCCATCGACACGATATCTGTCAGAGAAAAACAGGTG
CTCAAGCTGATAGCCAGAGGCATGGGCAACAAAGAAATCGCAGCGGAGCTGTGCATCAGCCACAAGACCGTGGAAAAACA
CAAAGCCAGCCTCAAACGTAAACTGAGAGTGAACAGCAACGCGGAGATGGCCACGCTGTCCATGGAGTACGGTCTGCTGG
AGCCCTGA

Upstream 100 bases:

>100_bases
TTACATGCAGCCGCATCACTCCGGTACGCAGTAAGTGAGGGCTTTACAAAGACGGTACAGTTGCCTAGGTTTCAGATAAT
TCACAGACAGGAATGTTTAT

Downstream 100 bases:

>100_bases
GCCGCGTCACCCGCCGCACAATATGCAGCCGCGCCCGCTCCACCGCGGGCTGCAACCTTCTTTGCCCCCCTGCATCGCGG
GATACCCGCAAAAATTACCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPKTVVIVEDMGIVREGVRALLGGCPGYRIAGEASDGIEALQVVERCAPDVVLMDIGMPRMDGADAIREIKRRFPRTKVI
ALTAHNKSALIFRTLHAGADGYMLKTGNCETLVGAIQTVLEGRRYISPDISQSLIDSLAGSDPMDFANPIDTISVREKQV
LKLIARGMGNKEIAAELCISHKTVEKHKASLKRKLRVNSNAEMATLSMEYGLLEP

Sequences:

>Translated_215_residues
MPKTVVIVEDMGIVREGVRALLGGCPGYRIAGEASDGIEALQVVERCAPDVVLMDIGMPRMDGADAIREIKRRFPRTKVI
ALTAHNKSALIFRTLHAGADGYMLKTGNCETLVGAIQTVLEGRRYISPDISQSLIDSLAGSDPMDFANPIDTISVREKQV
LKLIARGMGNKEIAAELCISHKTVEKHKASLKRKLRVNSNAEMATLSMEYGLLEP
>Mature_214_residues
PKTVVIVEDMGIVREGVRALLGGCPGYRIAGEASDGIEALQVVERCAPDVVLMDIGMPRMDGADAIREIKRRFPRTKVIA
LTAHNKSALIFRTLHAGADGYMLKTGNCETLVGAIQTVLEGRRYISPDISQSLIDSLAGSDPMDFANPIDTISVREKQVL
KLIARGMGNKEIAAELCISHKTVEKHKASLKRKLRVNSNAEMATLSMEYGLLEP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=35.4066985645933, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788521, Length=209, Percent_Identity=35.4066985645933, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=34.8258706467662, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=30.1075268817204, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786747, Length=212, Percent_Identity=27.3584905660377, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=29, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23402; Mature: 23270

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTVVIVEDMGIVREGVRALLGGCPGYRIAGEASDGIEALQVVERCAPDVVLMDIGMPR
CCCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCC
MDGADAIREIKRRFPRTKVIALTAHNKSALIFRTLHAGADGYMLKTGNCETLVGAIQTVL
CCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHH
EGRRYISPDISQSLIDSLAGSDPMDFANPIDTISVREKQVLKLIARGMGNKEIAAELCIS
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HKTVEKHKASLKRKLRVNSNAEMATLSMEYGLLEP
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
PKTVVIVEDMGIVREGVRALLGGCPGYRIAGEASDGIEALQVVERCAPDVVLMDIGMPR
CCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCC
MDGADAIREIKRRFPRTKVIALTAHNKSALIFRTLHAGADGYMLKTGNCETLVGAIQTVL
CCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHH
EGRRYISPDISQSLIDSLAGSDPMDFANPIDTISVREKQVLKLIARGMGNKEIAAELCIS
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HKTVEKHKASLKRKLRVNSNAEMATLSMEYGLLEP
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]