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The map label for this gene is comEB [H]

Identifier: 78357476

GI number: 78357476

Start: 2454557

End: 2455024

Strand: Direct

Name: comEB [H]

Synonym: Dde_2433

Alternate gene names: 78357476

Gene position: 2454557-2455024 (Clockwise)

Preceding gene: 78357475

Following gene: 304570589

Centisome position: 65.8

GC content: 56.84

Gene sequence:

>468_bases
ATGCACAGCAGACTTCCCTGGCCTCATTATTTTATGGACATCACCTATCTTGTGGCCGAGCGTTCCACCTGCACGCGGCG
CAAAGTGGGCGCCATCGCGGTCAAGGACAAACGCATTCTGGCCACCGGTTACAACGGTGCGCCCTCCAATGTGGCGCACT
GCCTTGATGTGGGCTGCCTGCGCGAAGAGCTGGGAGTGCCTTCCGGCCAGCGGCACGAAATATGCCGTGGCCTGCACGCC
GAACAGAACGTGATTATTCAGGCAGCCATCCACGGGGTATCACTGGCCGGTGCGGAAATATACTGCACCACGCAGCCCTG
CCTTATCTGCACAAAAATGCTGATAAACTGCGGAGTGACAGCAGTGTATTTCATGGAACCCTATCCGGACCCGCTCTCAG
AGGCCATGATGCGCGAAGCCGGAGTGAAATTTGAAGTGCTTGATTATCCTCAGGCCGGACGGAAATAG

Upstream 100 bases:

>100_bases
AACAGCAGACAAAGCAACATTGCAGCGGGGCGGTTTGACAAAACCGCCCCGCTATATTCACTGCTAAAGCCGCACACAGC
GCGGCACACGGATATCACGC

Downstream 100 bases:

>100_bases
CCGTGTCACACGATCATCCTTTTTCTTCCTTCATGCTTGAGGCGGTGGCGCTGGCCGAAAAAGGCCGCTGGGCCACATCG
CCCAATCCCTGCGTGGGTGC

Product: cytidine/deoxycytidylate deaminase family protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MHSRLPWPHYFMDITYLVAERSTCTRRKVGAIAVKDKRILATGYNGAPSNVAHCLDVGCLREELGVPSGQRHEICRGLHA
EQNVIIQAAIHGVSLAGAEIYCTTQPCLICTKMLINCGVTAVYFMEPYPDPLSEAMMREAGVKFEVLDYPQAGRK

Sequences:

>Translated_155_residues
MHSRLPWPHYFMDITYLVAERSTCTRRKVGAIAVKDKRILATGYNGAPSNVAHCLDVGCLREELGVPSGQRHEICRGLHA
EQNVIIQAAIHGVSLAGAEIYCTTQPCLICTKMLINCGVTAVYFMEPYPDPLSEAMMREAGVKFEVLDYPQAGRK
>Mature_155_residues
MHSRLPWPHYFMDITYLVAERSTCTRRKVGAIAVKDKRILATGYNGAPSNVAHCLDVGCLREELGVPSGQRHEICRGLHA
EQNVIIQAAIHGVSLAGAEIYCTTQPCLICTKMLINCGVTAVYFMEPYPDPLSEAMMREAGVKFEVLDYPQAGRK

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321938, Length=152, Percent_Identity=33.5526315789474, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 17153; Mature: 17153

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSRLPWPHYFMDITYLVAERSTCTRRKVGAIAVKDKRILATGYNGAPSNVAHCLDVGCL
CCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHH
REELGVPSGQRHEICRGLHAEQNVIIQAAIHGVSLAGAEIYCTTQPCLICTKMLINCGVT
HHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCEEEECCCHHHHHHHHHHHCCCE
AVYFMEPYPDPLSEAMMREAGVKFEVLDYPQAGRK
EEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure
MHSRLPWPHYFMDITYLVAERSTCTRRKVGAIAVKDKRILATGYNGAPSNVAHCLDVGCL
CCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHH
REELGVPSGQRHEICRGLHAEQNVIIQAAIHGVSLAGAEIYCTTQPCLICTKMLINCGVT
HHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCEEEECCCHHHHHHHHHHHCCCE
AVYFMEPYPDPLSEAMMREAGVKFEVLDYPQAGRK
EEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]