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The map label for this gene is yocR [H]

Identifier: 78357414

GI number: 78357414

Start: 2394087

End: 2395448

Strand: Reverse

Name: yocR [H]

Synonym: Dde_2371

Alternate gene names: 78357414

Gene position: 2395448-2394087 (Counterclockwise)

Preceding gene: 78357415

Following gene: 78357399

Centisome position: 64.22

GC content: 56.83

Gene sequence:

>1362_bases
ATGGCAACAAATCAACGCGACGGCTTTTCATCAAAGCTGGGGGTGCTGGCTGCGACTCTGGGGTCTGCGGTCGGGCTGGG
GAACATCTGGAAATTTCCCTATATGACAGGAGAAAACGGGGGCGCTTCGTTTCTTCTGCTTTACATCATAGCCACACTGG
TTGTGGGGCTTCCTATCATGATTGCGGAGATAATGATGGGCCGCAGGGCGCGCAGCAACGCCGTGGGCACATTCCGCAAG
CTGGCCCCGGGCACGCCGTGGTGGCTGGTGGGGCTTTCCGGATGCATCGCCGCGTTTGTCATTCTTTCCTTTTATACCAA
TGTGGTGGGCTGGGTGTTTTTTTACATCGTCAAGTCTGTCACCGGTGTGCTGAACGCCACAGACCCTAAAACAGGCGAAG
CGGTTTTCGGGGCCATGGTCAGCGCGCCGTGGTCTTCGCTGATGTGGCAGTGGGGGGTTCTGGTGCTCATCAGCTACATC
ATCATCGGCGGGGTGAGCAAAGGTATAGAAAAAACGACCAAAACACTGCTGCCCATTCTTTTTGTCATGCTGCTGCTTGT
CTGCGCGCGCTCGCTTACGCTGCCCAAGGCGGCGGAAGGGCTTGCCTTTCTGTTCAATCCCGATTTCAGCAAGATTACCG
GCAATGTGGTGCTGATGGCCATGGGGCTTGCATTTTTCAAGCTGTCCATCGGCATGGGCACCATGATGACTTACGGCAGC
TACTTCCGCGCCGACGCCAACATTCCCGTCACCACAACGCGTGTCATGCTGGCAGACCTCATGGTTTCCATGCTGGCGGG
CATTGCCATTTTTCCCGCTGTGTTCAACTTCGGCTTTGAACCGGCGGCCGGGCCGGGACTGCTGTTCATGACCATACCTG
CGGTATTCAGTGCCATGCCTGCGGGGCAGCTGTTCATGGTTGCTTTTTTTGTGCTTACGGGCATTGCGACCATCGGGGCC
ATGTTGTCGCTTATGGAAGTGCCGGTGGCTTTTCTGACAGAAGCCCTCGGCTGGTCGCGCAAGACGGCTACGGTGCTTAC
CGCGCTGCTGCTGGCGGTTACGGGCGCACCTGCCACGCTGTCGTTCAGCACCATGGCCGATGTAACCGTGTTCGGCATGA
ATTTTTTTGATTTTTACGATTACCTGTCGTCCAATATTCTGCTGCCCGCCGGCGGGCTGCTTATCTGTGTTTTCATCGGC
TGGGTGTGGGGCAGAAAGAATATGCAGGACGAGCTTTCCAACAGCGGAGAACTGCACAACACCTCTGTGGTGTCCGTGGT
GTTCCGGCTGGTGCGCTGGGTGACCCCCGTGTTGGTGCTGCTGGTCATGCTCAACGGTCTGGGTGTTATCAAGCTGGGCT
GA

Upstream 100 bases:

>100_bases
CAGATTATGGAAAAATTAGTTGAAACGTACAGCGTCTGCGACTAGGAAAATTCACCCGCCGGTATGTCCGGGGGTATCTT
TACGAGGAGAGTGAAGGAAT

Downstream 100 bases:

>100_bases
TTGTTCTGCTGCGCTGCAGTTCCTGACCCCTGCCGTTTTTGCGGCAGGGGTTTTTTGCGGTCACAGCCCGCAGTCAAATT
CAAGACATGCCAGCGCCTTT

Product: sodium-dependent symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MATNQRDGFSSKLGVLAATLGSAVGLGNIWKFPYMTGENGGASFLLLYIIATLVVGLPIMIAEIMMGRRARSNAVGTFRK
LAPGTPWWLVGLSGCIAAFVILSFYTNVVGWVFFYIVKSVTGVLNATDPKTGEAVFGAMVSAPWSSLMWQWGVLVLISYI
IIGGVSKGIEKTTKTLLPILFVMLLLVCARSLTLPKAAEGLAFLFNPDFSKITGNVVLMAMGLAFFKLSIGMGTMMTYGS
YFRADANIPVTTTRVMLADLMVSMLAGIAIFPAVFNFGFEPAAGPGLLFMTIPAVFSAMPAGQLFMVAFFVLTGIATIGA
MLSLMEVPVAFLTEALGWSRKTATVLTALLLAVTGAPATLSFSTMADVTVFGMNFFDFYDYLSSNILLPAGGLLICVFIG
WVWGRKNMQDELSNSGELHNTSVVSVVFRLVRWVTPVLVLLVMLNGLGVIKLG

Sequences:

>Translated_453_residues
MATNQRDGFSSKLGVLAATLGSAVGLGNIWKFPYMTGENGGASFLLLYIIATLVVGLPIMIAEIMMGRRARSNAVGTFRK
LAPGTPWWLVGLSGCIAAFVILSFYTNVVGWVFFYIVKSVTGVLNATDPKTGEAVFGAMVSAPWSSLMWQWGVLVLISYI
IIGGVSKGIEKTTKTLLPILFVMLLLVCARSLTLPKAAEGLAFLFNPDFSKITGNVVLMAMGLAFFKLSIGMGTMMTYGS
YFRADANIPVTTTRVMLADLMVSMLAGIAIFPAVFNFGFEPAAGPGLLFMTIPAVFSAMPAGQLFMVAFFVLTGIATIGA
MLSLMEVPVAFLTEALGWSRKTATVLTALLLAVTGAPATLSFSTMADVTVFGMNFFDFYDYLSSNILLPAGGLLICVFIG
WVWGRKNMQDELSNSGELHNTSVVSVVFRLVRWVTPVLVLLVMLNGLGVIKLG
>Mature_452_residues
ATNQRDGFSSKLGVLAATLGSAVGLGNIWKFPYMTGENGGASFLLLYIIATLVVGLPIMIAEIMMGRRARSNAVGTFRKL
APGTPWWLVGLSGCIAAFVILSFYTNVVGWVFFYIVKSVTGVLNATDPKTGEAVFGAMVSAPWSSLMWQWGVLVLISYII
IGGVSKGIEKTTKTLLPILFVMLLLVCARSLTLPKAAEGLAFLFNPDFSKITGNVVLMAMGLAFFKLSIGMGTMMTYGSY
FRADANIPVTTTRVMLADLMVSMLAGIAIFPAVFNFGFEPAAGPGLLFMTIPAVFSAMPAGQLFMVAFFVLTGIATIGAM
LSLMEVPVAFLTEALGWSRKTATVLTALLLAVTGAPATLSFSTMADVTVFGMNFFDFYDYLSSNILLPAGGLLICVFIGW
VWGRKNMQDELSNSGELHNTSVVSVVFRLVRWVTPVLVLLVMLNGLGVIKLG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=456, Percent_Identity=26.0964912280702, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI4507043, Length=418, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI58219014, Length=300, Percent_Identity=27.6666666666667, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI194018524, Length=299, Percent_Identity=31.438127090301, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI171184408, Length=471, Percent_Identity=24.8407643312102, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI171184406, Length=471, Percent_Identity=24.8407643312102, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI171184404, Length=471, Percent_Identity=24.8407643312102, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI21361581, Length=464, Percent_Identity=23.0603448275862, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI7657587, Length=465, Percent_Identity=23.6559139784946, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI33354281, Length=298, Percent_Identity=25.8389261744966, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI197276623, Length=472, Percent_Identity=25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI54607094, Length=472, Percent_Identity=25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI5032097, Length=475, Percent_Identity=24.4210526315789, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI134304856, Length=355, Percent_Identity=26.1971830985915, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI218563756, Length=464, Percent_Identity=24.1379310344828, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI51468073, Length=300, Percent_Identity=24.3333333333333, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI11181770, Length=307, Percent_Identity=26.0586319218241, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4507041, Length=499, Percent_Identity=22.0440881763527, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI289191351, Length=361, Percent_Identity=24.3767313019391, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4557046, Length=361, Percent_Identity=24.3767313019391, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI289191377, Length=361, Percent_Identity=24.3767313019391, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI21361693, Length=117, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI67782317, Length=467, Percent_Identity=23.3404710920771, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI67782313, Length=467, Percent_Identity=23.3404710920771, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI67782315, Length=467, Percent_Identity=23.3404710920771, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI12408638, Length=280, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI92859670, Length=124, Percent_Identity=33.8709677419355, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI197276625, Length=123, Percent_Identity=30.0813008130081, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI300360519, Length=285, Percent_Identity=23.5087719298246, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=468, Percent_Identity=26.4957264957265, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25146584, Length=399, Percent_Identity=24.3107769423559, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555248, Length=414, Percent_Identity=24.3961352657005, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=434, Percent_Identity=23.7327188940092, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71998244, Length=406, Percent_Identity=24.6305418719212, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=120, Percent_Identity=36.6666666666667, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI212642127, Length=118, Percent_Identity=34.7457627118644, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535731, Length=121, Percent_Identity=32.2314049586777, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133952791, Length=117, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136952, Length=451, Percent_Identity=23.5033259423503, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI45551088, Length=463, Percent_Identity=27.2138228941685, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281364394, Length=447, Percent_Identity=23.7136465324385, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574704, Length=447, Percent_Identity=23.7136465324385, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136950, Length=447, Percent_Identity=23.7136465324385, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574702, Length=447, Percent_Identity=23.7136465324385, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24652942, Length=463, Percent_Identity=27.2138228941685, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24639514, Length=472, Percent_Identity=24.1525423728814, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221329674, Length=472, Percent_Identity=24.1525423728814, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24639516, Length=309, Percent_Identity=27.1844660194175, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19921936, Length=500, Percent_Identity=24.2, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363702, Length=462, Percent_Identity=25.974025974026, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24762620, Length=355, Percent_Identity=25.3521126760563, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24655079, Length=298, Percent_Identity=27.8523489932886, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24661428, Length=494, Percent_Identity=24.4939271255061, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582567, Length=448, Percent_Identity=24.7767857142857, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281364136, Length=507, Percent_Identity=23.6686390532544, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363700, Length=345, Percent_Identity=26.9565217391304, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550877, Length=279, Percent_Identity=27.2401433691756, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45551183, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654186, Length=125, Percent_Identity=30.4, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582569, Length=409, Percent_Identity=23.2273838630807, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48487; Mature: 48355

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
ATNQRDGFSSKLGVLAATLGSAVGLGNIWKFPYMTGENGGASFLLLYIIATLVVGLPIM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]