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The map label for this gene is znuB [C]

Identifier: 78357253

GI number: 78357253

Start: 2250852

End: 2251673

Strand: Direct

Name: znuB [C]

Synonym: Dde_2210

Alternate gene names: 78357253

Gene position: 2250852-2251673 (Clockwise)

Preceding gene: 78357252

Following gene: 78357254

Centisome position: 60.34

GC content: 62.17

Gene sequence:

>822_bases
ATGATTGAAGCCCTTTCATATGACTTTATGCAGCACGCTTTGCTGGCGGCACTGCTGGCCAGCATCGCCTGCGGCATCAT
AGGCACGCTGGTGGTGGTCAACCGGCTGGTTTTTCTGGCCGGCGGAGTTGCCCATGCGGCATACGGCGGTGTCGGACTGG
CTTTTTATTTCGGGCTGCCCGTACTGCCGTGCACCCTCGGATTCTCTGTGGCCACCTCGCTGATCATGGCCGACATAGCC
CGACGCGACAGACAACGGGCCGATGCCGCCATAGGGGTTCTATGGGCTGCCGGCATGGCTGCCGGCATTATCCTGCTGGA
CCTCACCCCCGGATATAACGTGGATCTCATGAGCTATCTTTTCGGCAGCATCATGGCGGTTCCCGCCGGAGACCTGTGGC
TTATGGCGGGGCTGGATGCGGTCATCGTGAGCGCCGTAGCCTATTTTTACCAGCCGCTGCTGGTGGCATCGTTTGACGAA
GAATACGCAGCCGCGCGGGGTGTTCCGGCCAGACTCCTGTACCTGCTGCTCATCGCCATGGCGGCAGTCACCGTGGTCAT
GCTCATCCGCATTGCGGGGCTTATTCTTGTCATCGCGCTGCTTACGCTGCCCACTTTCGCCGCGGCGCGCACCGCGCGCA
CCATGGGCGGCATGATGTTTGCCTCCACGCTGTGGAGCATGGTGTTCTGCCTGTGCGGTCTGTGGCTTTCGTACATGTTC
AATCTGACATCCGGCGCGGCCATCATAGCCGCCGGAGTGGCGTGCGTCTGCGTCACAGCTGCGGCCTCGCGGCTGCGCAG
AGCGCGCACCGCCGCACTGTAG

Upstream 100 bases:

>100_bases
ATGCTGACCATGCTCTACGGCACTCACGATAAAACCTGCCCCATGGGCACATTCATCAACTCCGTTTCGACCATCTTTCC
CACGCTGCCGGAGAAAAAAC

Downstream 100 bases:

>100_bases
GATGGCATAATGACAGACAACCATCATACCGCCGGCGCTGAACAGTGCCTTTTGACGGCAGGGCTGGAAGCCACCCCCAA
CCGTCTGGCCGCACTGCGCG

Product: cation ABC transporter permease

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIEALSYDFMQHALLAALLASIACGIIGTLVVVNRLVFLAGGVAHAAYGGVGLAFYFGLPVLPCTLGFSVATSLIMADIA
RRDRQRADAAIGVLWAAGMAAGIILLDLTPGYNVDLMSYLFGSIMAVPAGDLWLMAGLDAVIVSAVAYFYQPLLVASFDE
EYAAARGVPARLLYLLLIAMAAVTVVMLIRIAGLILVIALLTLPTFAAARTARTMGGMMFASTLWSMVFCLCGLWLSYMF
NLTSGAAIIAAGVACVCVTAAASRLRRARTAAL

Sequences:

>Translated_273_residues
MIEALSYDFMQHALLAALLASIACGIIGTLVVVNRLVFLAGGVAHAAYGGVGLAFYFGLPVLPCTLGFSVATSLIMADIA
RRDRQRADAAIGVLWAAGMAAGIILLDLTPGYNVDLMSYLFGSIMAVPAGDLWLMAGLDAVIVSAVAYFYQPLLVASFDE
EYAAARGVPARLLYLLLIAMAAVTVVMLIRIAGLILVIALLTLPTFAAARTARTMGGMMFASTLWSMVFCLCGLWLSYMF
NLTSGAAIIAAGVACVCVTAAASRLRRARTAAL
>Mature_273_residues
MIEALSYDFMQHALLAALLASIACGIIGTLVVVNRLVFLAGGVAHAAYGGVGLAFYFGLPVLPCTLGFSVATSLIMADIA
RRDRQRADAAIGVLWAAGMAAGIILLDLTPGYNVDLMSYLFGSIMAVPAGDLWLMAGLDAVIVSAVAYFYQPLLVASFDE
EYAAARGVPARLLYLLLIAMAAVTVVMLIRIAGLILVIALLTLPTFAAARTARTMGGMMFASTLWSMVFCLCGLWLSYMF
NLTSGAAIIAAGVACVCVTAAASRLRRARTAAL

Specific function: Involved In The High-Affinity Zinc Uptake Transport System. [C]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=240, Percent_Identity=28.75, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28602; Mature: 28602

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEALSYDFMQHALLAALLASIACGIIGTLVVVNRLVFLAGGVAHAAYGGVGLAFYFGLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VLPCTLGFSVATSLIMADIARRDRQRADAAIGVLWAAGMAAGIILLDLTPGYNVDLMSYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHH
FGSIMAVPAGDLWLMAGLDAVIVSAVAYFYQPLLVASFDEEYAAARGVPARLLYLLLIAM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
AAVTVVMLIRIAGLILVIALLTLPTFAAARTARTMGGMMFASTLWSMVFCLCGLWLSYMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLTSGAAIIAAGVACVCVTAAASRLRRARTAAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEALSYDFMQHALLAALLASIACGIIGTLVVVNRLVFLAGGVAHAAYGGVGLAFYFGLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VLPCTLGFSVATSLIMADIARRDRQRADAAIGVLWAAGMAAGIILLDLTPGYNVDLMSYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHH
FGSIMAVPAGDLWLMAGLDAVIVSAVAYFYQPLLVASFDEEYAAARGVPARLLYLLLIAM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
AAVTVVMLIRIAGLILVIALLTLPTFAAARTARTMGGMMFASTLWSMVFCLCGLWLSYMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLTSGAAIIAAGVACVCVTAAASRLRRARTAAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]