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The map label for this gene is ppaX [H]

Identifier: 78357233

GI number: 78357233

Start: 2230433

End: 2231137

Strand: Direct

Name: ppaX [H]

Synonym: Dde_2190

Alternate gene names: 78357233

Gene position: 2230433-2231137 (Clockwise)

Preceding gene: 78357231

Following gene: 78357239

Centisome position: 59.79

GC content: 57.3

Gene sequence:

>705_bases
ATGTTATCACGGCACGCTTTGCAAGCGATCGCGTTCGATTTTGACGGAACGCTTGCAGACTCAAGAATAGACTTCACCGA
GATGAGGGCCGCACTGCACGCAACGGTCAGCCGCTTCATGCAGCCGCCTTCTGACAGCGGTATGTATATACTGGAATGGC
TGGAAGCTGCAGAAAACGAACTGGCAGAAACATCAGCACCACAGGCGGCCCTGCTCAAGCAGGCCACGCTGAAAACCATA
GAAGAAATAGAAGTGGCTGCCGCACGCAGAGGGCAGATGTTTTCCGGAGCTGTGCATATGCTGCAACAGCTGAAATCCGC
AGGCATTTCCACATATATCGTCACAAGAAACTGCCGCGCCGGAGTGCTGGCCATGCTGCCGGAAGCATACTCGCTGTGCA
CGGGTGTTTTCACCCGTGACGACGTGACCGCAGTCAAACCGGACCCCCGCCATCTGACGCAGGCTCTTGCGGTCTGCGGC
TGTCCGGCGCAGAATGCTCTTATGGTGGGTGATCACCCCATGGATATTCTGATGGGAAAACAGGCCGGAGCCGTCACAGC
CGGAGTGACCACCGGCGAAGGAAATCATGAAACCCTGCAGCAGGCCGGTGCGGACTACATAGCGGACAGTCTGCAAGAAC
TTATGCAAAGCATCGGGCCTGCCCTTGCCGCGGCAAAACAGCAGCCCCGGAAAGACCGCCCCTGA

Upstream 100 bases:

>100_bases
CATCGTACCTGAAAAGACCATTGCCAGACACACAAGGCTCCCGTAACATCCATGCGCCGGAGCATAAAGCACGAGCAGTT
TCAAGAGGATAGGAAAGACT

Downstream 100 bases:

>100_bases
GTGCTACGCGGAATATACCGTCACCGCCGCACCGCCGTAAAAAAGGCGATGGCGTTCCAACTCCCTCAGGCCCTGCCGGT
GGGCCAGCCCCTGCATGCCT

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLSRHALQAIAFDFDGTLADSRIDFTEMRAALHATVSRFMQPPSDSGMYILEWLEAAENELAETSAPQAALLKQATLKTI
EEIEVAAARRGQMFSGAVHMLQQLKSAGISTYIVTRNCRAGVLAMLPEAYSLCTGVFTRDDVTAVKPDPRHLTQALAVCG
CPAQNALMVGDHPMDILMGKQAGAVTAGVTTGEGNHETLQQAGADYIADSLQELMQSIGPALAAAKQQPRKDRP

Sequences:

>Translated_234_residues
MLSRHALQAIAFDFDGTLADSRIDFTEMRAALHATVSRFMQPPSDSGMYILEWLEAAENELAETSAPQAALLKQATLKTI
EEIEVAAARRGQMFSGAVHMLQQLKSAGISTYIVTRNCRAGVLAMLPEAYSLCTGVFTRDDVTAVKPDPRHLTQALAVCG
CPAQNALMVGDHPMDILMGKQAGAVTAGVTTGEGNHETLQQAGADYIADSLQELMQSIGPALAAAKQQPRKDRP
>Mature_234_residues
MLSRHALQAIAFDFDGTLADSRIDFTEMRAALHATVSRFMQPPSDSGMYILEWLEAAENELAETSAPQAALLKQATLKTI
EEIEVAAARRGQMFSGAVHMLQQLKSAGISTYIVTRNCRAGVLAMLPEAYSLCTGVFTRDDVTAVKPDPRHLTQALAVCG
CPAQNALMVGDHPMDILMGKQAGAVTAGVTTGEGNHETLQQAGADYIADSLQELMQSIGPALAAAKQQPRKDRP

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 25069; Mature: 25069

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRHALQAIAFDFDGTLADSRIDFTEMRAALHATVSRFMQPPSDSGMYILEWLEAAENE
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LAETSAPQAALLKQATLKTIEEIEVAAARRGQMFSGAVHMLQQLKSAGISTYIVTRNCRA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCH
GVLAMLPEAYSLCTGVFTRDDVTAVKPDPRHLTQALAVCGCPAQNALMVGDHPMDILMGK
HHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCC
QAGAVTAGVTTGEGNHETLQQAGADYIADSLQELMQSIGPALAAAKQQPRKDRP
CCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSRHALQAIAFDFDGTLADSRIDFTEMRAALHATVSRFMQPPSDSGMYILEWLEAAENE
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LAETSAPQAALLKQATLKTIEEIEVAAARRGQMFSGAVHMLQQLKSAGISTYIVTRNCRA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCH
GVLAMLPEAYSLCTGVFTRDDVTAVKPDPRHLTQALAVCGCPAQNALMVGDHPMDILMGK
HHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCC
QAGAVTAGVTTGEGNHETLQQAGADYIADSLQELMQSIGPALAAAKQQPRKDRP
CCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9465101; 12359880 [H]