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The map label for this gene is tolQ [C]

Identifier: 78357196

GI number: 78357196

Start: 2198797

End: 2200221

Strand: Direct

Name: tolQ [C]

Synonym: Dde_2153

Alternate gene names: 78357196

Gene position: 2198797-2200221 (Clockwise)

Preceding gene: 78357195

Following gene: 78357197

Centisome position: 58.95

GC content: 54.18

Gene sequence:

>1425_bases
ATGAAATACAAAATACTCACACTGGTTACACTGCTGATAACCGCCAGCGTGCCGGCACACGCCCAGTGGTCCGGTGCGGT
GGCTGAAACCCGCAAACTGGCTGCGGAAACCCGCTCAGAGGCAGCCAAAACCCGCGACCTGATAACATCGGAAAAAAAAG
CTGTGGTGAACGAAAAAGCGCAGCTTGAAAAAGTGATTGCCGCCAAGCACAAGCAGCACGAAGAGCTTAAAGCCAGATAC
GAAGCTTTGCTGCAGCAGGAAGCCCGACTGAAAGAGGAGCTGGCGCAGCAGGCCCATGAACTGAAAACCATTGACGGCAC
CATCCGCACTTCAGCCAAGCAGGCCAGAGACTATTTTCACGAAAGTCTCACAACACCTGAATTTCCGCATCGTGAACCGG
TGCTGAGCGTCATCCTGACTCCGGAAACCTTTCCCGGACTTGAAGGCATAAAAAATCTGCTGCGGCTTTATATGGAAGAG
ATGTCCGCCTCAGGACGTGTACAGCTTCGCGAAGGGTCTTTTGTCAATGCTGACGGACGCACAGAAACCGCCCGACTGCT
GCGTATAGGCACATTCACAGCGGCCTTTAAAAAACAGGACGGCACTGCCGGATTTCTGCGTCCCCTGCATGAAGGTTCGT
TACTGGGCGCTGTTCCGGGAAATCCCGGCTGGACGCTGGGACGCGGAATGCGGGCGTACTTTGAAGGCGAAAGCGATACC
TTTCCGGTAGATATTTCCAACGGAGCGGCGCTGGCCAGGCTGGAGCAGGACCAGAAAGGAATATACGAGTGGCTCCAGAC
AGGCGGCCTGCTGGTATGGCCCATCATTCTGGTGGGCATCATCGCGCTGGGCCTTGTTATTGAACGTTTTTACACACTGG
GCAGGCTGCGCGGAAATTCTGACAGAAACATGCAGACCATACTGTCCATGATTCGTGCCAGAAAATGGCATGAGTGTCAG
GAATTCTGCGCGAGGGCTTCCAATTTTCCCACATGCCGTATCATAGGACATACTCTGGGATATATGGGGGCAACCCGCGA
GATTATTGAAAACGCTTATCAGGAAGCAATGCTCAAAGAGTTGCCTGTTCTGGAACGCTTTCTGCCCACACTCAGCGTGC
TGGCAGCGGTGGCGCCGCTTCTGGGGCTTCTGGGTACCGTCACCGGCATGATCAACACCTTTCAGACAATCACACTGTAC
GGTACCGGCGACCCGCGCATGATGTCGGGCGGTATTTCAGAAGCATTGATCACCACTCAGCTGGGACTGGCCGTGGCCGT
GCCCATCATGATTCTGCATCACATTCTGGAACGGCGGGTAGATGCTCTGATGGGCGACATGGAAGAAAAAGGAACAAGCT
TTACTGTAGCACTGATGCAGCAGGGCCAGATACGACAGGGAGAATCATACGGTGCAGCTGCATGA

Upstream 100 bases:

>100_bases
CTCTCGATCAGGATACCGCCCGCACCCTGCACAAAGCTGAAGAAATGGCGGCGCGCAAACGTGCAGTTGAGCTTCTGCAA
CTACCCATCGGAAAGGTACA

Downstream 100 bases:

>100_bases
TTATCTTGAACAGGTGCTGGTGTATTTTAATGCCGGAGGGCCGACTATGGTTCCTATCATGGCATTCTCGTTTGCCATCT
GGCTTATAATATTACTCAAA

Product: TolQ-like transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MKYKILTLVTLLITASVPAHAQWSGAVAETRKLAAETRSEAAKTRDLITSEKKAVVNEKAQLEKVIAAKHKQHEELKARY
EALLQQEARLKEELAQQAHELKTIDGTIRTSAKQARDYFHESLTTPEFPHREPVLSVILTPETFPGLEGIKNLLRLYMEE
MSASGRVQLREGSFVNADGRTETARLLRIGTFTAAFKKQDGTAGFLRPLHEGSLLGAVPGNPGWTLGRGMRAYFEGESDT
FPVDISNGAALARLEQDQKGIYEWLQTGGLLVWPIILVGIIALGLVIERFYTLGRLRGNSDRNMQTILSMIRARKWHECQ
EFCARASNFPTCRIIGHTLGYMGATREIIENAYQEAMLKELPVLERFLPTLSVLAAVAPLLGLLGTVTGMINTFQTITLY
GTGDPRMMSGGISEALITTQLGLAVAVPIMILHHILERRVDALMGDMEEKGTSFTVALMQQGQIRQGESYGAAA

Sequences:

>Translated_474_residues
MKYKILTLVTLLITASVPAHAQWSGAVAETRKLAAETRSEAAKTRDLITSEKKAVVNEKAQLEKVIAAKHKQHEELKARY
EALLQQEARLKEELAQQAHELKTIDGTIRTSAKQARDYFHESLTTPEFPHREPVLSVILTPETFPGLEGIKNLLRLYMEE
MSASGRVQLREGSFVNADGRTETARLLRIGTFTAAFKKQDGTAGFLRPLHEGSLLGAVPGNPGWTLGRGMRAYFEGESDT
FPVDISNGAALARLEQDQKGIYEWLQTGGLLVWPIILVGIIALGLVIERFYTLGRLRGNSDRNMQTILSMIRARKWHECQ
EFCARASNFPTCRIIGHTLGYMGATREIIENAYQEAMLKELPVLERFLPTLSVLAAVAPLLGLLGTVTGMINTFQTITLY
GTGDPRMMSGGISEALITTQLGLAVAVPIMILHHILERRVDALMGDMEEKGTSFTVALMQQGQIRQGESYGAAA
>Mature_474_residues
MKYKILTLVTLLITASVPAHAQWSGAVAETRKLAAETRSEAAKTRDLITSEKKAVVNEKAQLEKVIAAKHKQHEELKARY
EALLQQEARLKEELAQQAHELKTIDGTIRTSAKQARDYFHESLTTPEFPHREPVLSVILTPETFPGLEGIKNLLRLYMEE
MSASGRVQLREGSFVNADGRTETARLLRIGTFTAAFKKQDGTAGFLRPLHEGSLLGAVPGNPGWTLGRGMRAYFEGESDT
FPVDISNGAALARLEQDQKGIYEWLQTGGLLVWPIILVGIIALGLVIERFYTLGRLRGNSDRNMQTILSMIRARKWHECQ
EFCARASNFPTCRIIGHTLGYMGATREIIENAYQEAMLKELPVLERFLPTLSVLAAVAPLLGLLGTVTGMINTFQTITLY
GTGDPRMMSGGISEALITTQLGLAVAVPIMILHHILERRVDALMGDMEEKGTSFTVALMQQGQIRQGESYGAAA

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 52315; Mature: 52315

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKILTLVTLLITASVPAHAQWSGAVAETRKLAAETRSEAAKTRDLITSEKKAVVNEKA
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLEKVIAAKHKQHEELKARYEALLQQEARLKEELAQQAHELKTIDGTIRTSAKQARDYFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLTTPEFPHREPVLSVILTPETFPGLEGIKNLLRLYMEEMSASGRVQLREGSFVNADGR
HHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCC
TETARLLRIGTFTAAFKKQDGTAGFLRPLHEGSLLGAVPGNPGWTLGRGMRAYFEGESDT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCCCCHHCCCHHHCCCCCCC
FPVDISNGAALARLEQDQKGIYEWLQTGGLLVWPIILVGIIALGLVIERFYTLGRLRGNS
CCEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRNMQTILSMIRARKWHECQEFCARASNFPTCRIIGHTLGYMGATREIIENAYQEAMLKE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLERFLPTLSVLAAVAPLLGLLGTVTGMINTFQTITLYGTGDPRMMSGGISEALITTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHCCCHHHHHHHHH
LGLAVAVPIMILHHILERRVDALMGDMEEKGTSFTVALMQQGQIRQGESYGAAA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKYKILTLVTLLITASVPAHAQWSGAVAETRKLAAETRSEAAKTRDLITSEKKAVVNEKA
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLEKVIAAKHKQHEELKARYEALLQQEARLKEELAQQAHELKTIDGTIRTSAKQARDYFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLTTPEFPHREPVLSVILTPETFPGLEGIKNLLRLYMEEMSASGRVQLREGSFVNADGR
HHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCC
TETARLLRIGTFTAAFKKQDGTAGFLRPLHEGSLLGAVPGNPGWTLGRGMRAYFEGESDT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCCCCHHCCCHHHCCCCCCC
FPVDISNGAALARLEQDQKGIYEWLQTGGLLVWPIILVGIIALGLVIERFYTLGRLRGNS
CCEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRNMQTILSMIRARKWHECQEFCARASNFPTCRIIGHTLGYMGATREIIENAYQEAMLKE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLERFLPTLSVLAAVAPLLGLLGTVTGMINTFQTITLYGTGDPRMMSGGISEALITTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHCCCHHHHHHHHH
LGLAVAVPIMILHHILERRVDALMGDMEEKGTSFTVALMQQGQIRQGESYGAAA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]