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The map label for this gene is yyaE [H]

Identifier: 78357133

GI number: 78357133

Start: 2136520

End: 2138457

Strand: Direct

Name: yyaE [H]

Synonym: Dde_2090

Alternate gene names: 78357133

Gene position: 2136520-2138457 (Clockwise)

Preceding gene: 78357132

Following gene: 78357140

Centisome position: 57.28

GC content: 59.08

Gene sequence:

>1938_bases
ATGACACAGCTCGTAACAGGCTGCACACTCGACTGTCCGGACTGCTGCTCCATGGTGGCCGTACCCCGGCAAGACGGCAC
CCTGTCCATACAGGGCAATCCGGCACATCCTTTTACTCAGGGGCTCATCTGCGGCAAAGGAAAAAACTTCGTACAGCGCC
TGCAATCGTCCGAACGTATCACAACGCCTCTTGTGCGCCGCAACGGTACGCTCCGCAAAGCTTCGTGGGACGAAGCGCTG
TCTGTATGTGCCGCGAAAATAGATGCCCTGCGCGCCACCCCGGAAAAAATGCTGCATATACGGGGTGCAGGAACCCGCGG
AGTTCTCTTCGACGCCGCGGGAGAACTGCCCGCCCGCCTGCGTATGGCTGCCACGCACGGCTCGCTGTGCGACGAGACAG
GTATCGAAGCGTGCAAGGCTGACTTCGGTTCGCTGAATATGAACCATCCCCACGATCTTTTTAATGCAGACCGCATTGTA
AACTGGGGACGCGACATTTCACGCTCGTCGGTTCATCTGGCAAAAATTGTCAATGAAGCCAGAAAAAAGGGAACACAGGT
TCTGCTCATAAGTCCCTGCCCGTCAGGCGCCGCAGGCTATGCCGACGAAGTTATCACAGTACGCCCGGGTACAGACCGCT
TTCTGGCCGCCGCGGCGGCCAGACGACTGCTGACGCGCCCCGGTTTCCGTCAGCGCCTTTTACGCTGTTCTGCCAATGCA
GACGCATACCTTGCCTGCCTTGACGCCATGGATGAACACGCCCTGCTGACGGCGTGCGATGTATCAACCGCCGCTCTGGA
AAAACTGACAGACTGGTACGCCGACACGGATGCCGCTGTATCAACCCTGCTGGGATGGGGGCTGCAGCGCTACATACGCG
GCGCCCAGAACGTCAGGCACATAAATGCCCTTGCCATGATAAGCGGCCATATAGGAAAAAACGGCGCCGGTGTTTTCTAC
AACATATCGTCGTCACGGAACTTCAACCGCCAGTGGATGCAGGATCTTCCGGAACCTTCGCGCAGGTTGAGTCTGCCGCG
CATAGGGCAGGAGCTTGCCGGTGCAGCCCCCCCTGTGGAGCTGGTACTGTGCAGGGGCATCAATTTCGTCAACCAGTGCC
CTGATTCACACACCACAGCAGCGGCTCTCCGGCATGCATTTGTTATTGTCCTCGATGCATTTATGAACGATACAGCCGCA
CTGGCAGACGTCCTTCTGCCGTGCAGCCTGATGCTGGAACGGGAAGAAATAGTCGGATCCTTCATGCACAACCAGATAAA
CTACTGCGCACCGGTGTTTCCGCCGCCCGGTGAATGCCGCGACGACTTTGACATACTGGATGAGCTGGGCAGCAGGCTTT
CTGAACCGGTGCGTCTGCCGGACAGAGAGACATGCCTGCGTCGCGCGCTTGATTCCCCGCTTCTGCAGACAACGCTTTCC
CGTCTGCGGCAGGAGGGATTCGCCACCGCCGAACACCCGTTCATCGCATATGAAGGTATGCGTACAGACCATCAGGATGG
CCTGTTCCATTGTGTCGCCGAACTTTCACCTGACAAGGAAGATTCCGGAGACTACCCGTTTTTCCTGCTGACCCTCATAA
GCCGCAACACACTGCATTCACAGATTCCTGCCGGGATGCAACAGGGCCTGCCGGAACTTGCCGCAGCGCCTTGCGCGGCA
CAGGCGGCGGGCATCGCAGACGGCGAAGCTGCTTTACTTTGCACACCCGGCGGCCAGATGCAGGTCACCGTCCGCTTTGA
TCCCGCTATTCATCCTTCCGCCGTGCGGTTGCGGCGCGGTGGCTGGGTCAGCCGCGGCTGGGGGGCCAACGGGCTTACAG
CCCCGCTGGTTACAGATGCCGGAGAAGGCGCGGCCTTCTACAGCCAGAAAGCCGCTATCAAAAAGTTGCAGGCAGAACCG
CCGCACCCGCAGGCATGA

Upstream 100 bases:

>100_bases
TATAAGGATGTGGACCATGTGACTGATACGGCCTGCGCGACAGGCATTGCCCGCAAAGTGGCAAGACTGCGCCCTCTGAT
CTGCATAAAAGGATAACGAC

Downstream 100 bases:

>100_bases
GATGTAATTCTTCCCTGCTCGGTATGGAAATGCGCATGCCGTTCAGCACCGAATAATAAAAAACCCCGCTCCGGAAAAGA
GCGGGGATAAAAGCAGCACA

Product: molybdopterin oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MTQLVTGCTLDCPDCCSMVAVPRQDGTLSIQGNPAHPFTQGLICGKGKNFVQRLQSSERITTPLVRRNGTLRKASWDEAL
SVCAAKIDALRATPEKMLHIRGAGTRGVLFDAAGELPARLRMAATHGSLCDETGIEACKADFGSLNMNHPHDLFNADRIV
NWGRDISRSSVHLAKIVNEARKKGTQVLLISPCPSGAAGYADEVITVRPGTDRFLAAAAARRLLTRPGFRQRLLRCSANA
DAYLACLDAMDEHALLTACDVSTAALEKLTDWYADTDAAVSTLLGWGLQRYIRGAQNVRHINALAMISGHIGKNGAGVFY
NISSSRNFNRQWMQDLPEPSRRLSLPRIGQELAGAAPPVELVLCRGINFVNQCPDSHTTAAALRHAFVIVLDAFMNDTAA
LADVLLPCSLMLEREEIVGSFMHNQINYCAPVFPPPGECRDDFDILDELGSRLSEPVRLPDRETCLRRALDSPLLQTTLS
RLRQEGFATAEHPFIAYEGMRTDHQDGLFHCVAELSPDKEDSGDYPFFLLTLISRNTLHSQIPAGMQQGLPELAAAPCAA
QAAGIADGEAALLCTPGGQMQVTVRFDPAIHPSAVRLRRGGWVSRGWGANGLTAPLVTDAGEGAAFYSQKAAIKKLQAEP
PHPQA

Sequences:

>Translated_645_residues
MTQLVTGCTLDCPDCCSMVAVPRQDGTLSIQGNPAHPFTQGLICGKGKNFVQRLQSSERITTPLVRRNGTLRKASWDEAL
SVCAAKIDALRATPEKMLHIRGAGTRGVLFDAAGELPARLRMAATHGSLCDETGIEACKADFGSLNMNHPHDLFNADRIV
NWGRDISRSSVHLAKIVNEARKKGTQVLLISPCPSGAAGYADEVITVRPGTDRFLAAAAARRLLTRPGFRQRLLRCSANA
DAYLACLDAMDEHALLTACDVSTAALEKLTDWYADTDAAVSTLLGWGLQRYIRGAQNVRHINALAMISGHIGKNGAGVFY
NISSSRNFNRQWMQDLPEPSRRLSLPRIGQELAGAAPPVELVLCRGINFVNQCPDSHTTAAALRHAFVIVLDAFMNDTAA
LADVLLPCSLMLEREEIVGSFMHNQINYCAPVFPPPGECRDDFDILDELGSRLSEPVRLPDRETCLRRALDSPLLQTTLS
RLRQEGFATAEHPFIAYEGMRTDHQDGLFHCVAELSPDKEDSGDYPFFLLTLISRNTLHSQIPAGMQQGLPELAAAPCAA
QAAGIADGEAALLCTPGGQMQVTVRFDPAIHPSAVRLRRGGWVSRGWGANGLTAPLVTDAGEGAAFYSQKAAIKKLQAEP
PHPQA
>Mature_644_residues
TQLVTGCTLDCPDCCSMVAVPRQDGTLSIQGNPAHPFTQGLICGKGKNFVQRLQSSERITTPLVRRNGTLRKASWDEALS
VCAAKIDALRATPEKMLHIRGAGTRGVLFDAAGELPARLRMAATHGSLCDETGIEACKADFGSLNMNHPHDLFNADRIVN
WGRDISRSSVHLAKIVNEARKKGTQVLLISPCPSGAAGYADEVITVRPGTDRFLAAAAARRLLTRPGFRQRLLRCSANAD
AYLACLDAMDEHALLTACDVSTAALEKLTDWYADTDAAVSTLLGWGLQRYIRGAQNVRHINALAMISGHIGKNGAGVFYN
ISSSRNFNRQWMQDLPEPSRRLSLPRIGQELAGAAPPVELVLCRGINFVNQCPDSHTTAAALRHAFVIVLDAFMNDTAAL
ADVLLPCSLMLEREEIVGSFMHNQINYCAPVFPPPGECRDDFDILDELGSRLSEPVRLPDRETCLRRALDSPLLQTTLSR
LRQEGFATAEHPFIAYEGMRTDHQDGLFHCVAELSPDKEDSGDYPFFLLTLISRNTLHSQIPAGMQQGLPELAAAPCAAQ
AAGIADGEAALLCTPGGQMQVTVRFDPAIHPSAVRLRRGGWVSRGWGANGLTAPLVTDAGEGAAFYSQKAAIKKLQAEPP
HPQA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI171474008, Length=755, Percent_Identity=21.8543046357616, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI3868721, Length=623, Percent_Identity=21.8298555377207, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 69795; Mature: 69664

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLVTGCTLDCPDCCSMVAVPRQDGTLSIQGNPAHPFTQGLICGKGKNFVQRLQSSERI
CCCCCCCCCCCCHHHHHHHEECCCCCEEEEECCCCCCHHHCCEECCCHHHHHHHHCCCCC
TTPLVRRNGTLRKASWDEALSVCAAKIDALRATPEKMLHIRGAGTRGVLFDAAGELPARL
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCEEEECCCCCCHHH
RMAATHGSLCDETGIEACKADFGSLNMNHPHDLFNADRIVNWGRDISRSSVHLAKIVNEA
EEHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
RKKGTQVLLISPCPSGAAGYADEVITVRPGTDRFLAAAAARRLLTRPGFRQRLLRCSANA
HHCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DAYLACLDAMDEHALLTACDVSTAALEKLTDWYADTDAAVSTLLGWGLQRYIRGAQNVRH
CHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
INALAMISGHIGKNGAGVFYNISSSRNFNRQWMQDLPEPSRRLSLPRIGQELAGAAPPVE
HHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCHH
LVLCRGINFVNQCPDSHTTAAALRHAFVIVLDAFMNDTAALADVLLPCSLMLEREEIVGS
HHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FMHNQINYCAPVFPPPGECRDDFDILDELGSRLSEPVRLPDRETCLRRALDSPLLQTTLS
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHH
RLRQEGFATAEHPFIAYEGMRTDHQDGLFHCVAELSPDKEDSGDYPFFLLTLISRNTLHS
HHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QIPAGMQQGLPELAAAPCAAQAAGIADGEAALLCTPGGQMQVTVRFDPAIHPSAVRLRRG
HCCCHHHHCCHHHHHCCCHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHCC
GWVSRGWGANGLTAPLVTDAGEGAAFYSQKAAIKKLQAEPPHPQA
CCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQLVTGCTLDCPDCCSMVAVPRQDGTLSIQGNPAHPFTQGLICGKGKNFVQRLQSSERI
CCCCCCCCCCCHHHHHHHEECCCCCEEEEECCCCCCHHHCCEECCCHHHHHHHHCCCCC
TTPLVRRNGTLRKASWDEALSVCAAKIDALRATPEKMLHIRGAGTRGVLFDAAGELPARL
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCEEEECCCCCCHHH
RMAATHGSLCDETGIEACKADFGSLNMNHPHDLFNADRIVNWGRDISRSSVHLAKIVNEA
EEHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
RKKGTQVLLISPCPSGAAGYADEVITVRPGTDRFLAAAAARRLLTRPGFRQRLLRCSANA
HHCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DAYLACLDAMDEHALLTACDVSTAALEKLTDWYADTDAAVSTLLGWGLQRYIRGAQNVRH
CHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
INALAMISGHIGKNGAGVFYNISSSRNFNRQWMQDLPEPSRRLSLPRIGQELAGAAPPVE
HHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCHH
LVLCRGINFVNQCPDSHTTAAALRHAFVIVLDAFMNDTAALADVLLPCSLMLEREEIVGS
HHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FMHNQINYCAPVFPPPGECRDDFDILDELGSRLSEPVRLPDRETCLRRALDSPLLQTTLS
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHH
RLRQEGFATAEHPFIAYEGMRTDHQDGLFHCVAELSPDKEDSGDYPFFLLTLISRNTLHS
HHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QIPAGMQQGLPELAAAPCAAQAAGIADGEAALLCTPGGQMQVTVRFDPAIHPSAVRLRRG
HCCCHHHHCCHHHHHCCCHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHCC
GWVSRGWGANGLTAPLVTDAGEGAAFYSQKAAIKKLQAEPPHPQA
CCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1552862 [H]