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The map label for this gene is glyQ

Identifier: 78357077

GI number: 78357077

Start: 2075331

End: 2076215

Strand: Reverse

Name: glyQ

Synonym: Dde_2034

Alternate gene names: 78357077

Gene position: 2076215-2075331 (Counterclockwise)

Preceding gene: 78357078

Following gene: 78357076

Centisome position: 55.66

GC content: 53.56

Gene sequence:

>885_bases
ATGAACTTTCAAGACGTTATCCTTACGCTGCAGAATTTCTGGGCCCGCAGAGGCTGTGCCATACAGCAGCCTTTTGACAG
CGAATGTGGTGCGGGGACGTTCAACCCTGCCACCTTTCTTCGCGTGATCGGCCCCGAACCGTGGAATGTGGCGTATGTGG
AACCATCCAGACGTCCCACGGATGGCCGCTACGGAGAAAATCCCAACCGCCTGCAGCATTATTTTCAGTTTCAGGTCATT
CTCAAACCTTCTCCCGACAATGTGCAGGAGATTTATATCGACAGCCTGCGCGCTCTTGGCATCAACCCCGCAGAACACGA
CATCCGGTTTGTGGAAGATGACTGGGAATCGCCGACGCTCGGGGCATGGGGGCTCGGCTGGGAAGTCTGGCTCAATGGTA
TGGAAGTCACTCAGTTCACGTATTTTCAGCAGGTCGGCGGCATTGATCTAAGCCCGACAAGTGTCGAGATTACCTACGGT
CTTGAGCGGCTGTGCATGTATCTGCAGGAAAAAGAGTCGGTCTATGACCTGATGTGGAATGACACTGTGACATACGGGCA
TATCTACCATCGGAACGAAGTAGAAATGTCCCGTTACAATTTCGAAGAAAGTGATGCGGGCATGCTGCTGGAACTTTTCA
ATGCGTACGAGCGCGAATGCACCCGCCTGTGTGAAAAGCAGCTTCTCTGGCCTGCGTATGACTATTGCCTCAAGTGCTCG
CATACGTTCAACCTGCTGGATGCTCGCGGAGCGATTTCCATTACGGAACGCACGGGGTATATCGGCAGAGTGCGTGTGCT
TGCTTCTTCCGTGGCGCGGCTGTATGCCGCACAGCGTGAGGAAATGGGCTATCCCATGCTCAATACCGGAATCAGGAAAG
GATAG

Upstream 100 bases:

>100_bases
ATGTAGGCCTTGTCTGGGATAAGGGCCGGTTCCGCAGAATATGACGGGACGGACCGTTCCGGCCGGATGGTGTACTATTT
ATAGTGATTTAGGGGAAAAT

Downstream 100 bases:

>100_bases
GGGAGTCATATATGTCTGTTTTCGTGATGGAGATTGGAACAGAAGAACTGCCTGCCCGTTTCCTTTCCGGACTGGAGCAG
GAGATTGCTTCGCGGTTTGA

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNFQDVILTLQNFWARRGCAIQQPFDSECGAGTFNPATFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYFQFQVI
LKPSPDNVQEIYIDSLRALGINPAEHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDLSPTSVEITYG
LERLCMYLQEKESVYDLMWNDTVTYGHIYHRNEVEMSRYNFEESDAGMLLELFNAYERECTRLCEKQLLWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRVLASSVARLYAAQREEMGYPMLNTGIRKG

Sequences:

>Translated_294_residues
MNFQDVILTLQNFWARRGCAIQQPFDSECGAGTFNPATFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYFQFQVI
LKPSPDNVQEIYIDSLRALGINPAEHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDLSPTSVEITYG
LERLCMYLQEKESVYDLMWNDTVTYGHIYHRNEVEMSRYNFEESDAGMLLELFNAYERECTRLCEKQLLWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRVLASSVARLYAAQREEMGYPMLNTGIRKG
>Mature_294_residues
MNFQDVILTLQNFWARRGCAIQQPFDSECGAGTFNPATFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYFQFQVI
LKPSPDNVQEIYIDSLRALGINPAEHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDLSPTSVEITYG
LERLCMYLQEKESVYDLMWNDTVTYGHIYHRNEVEMSRYNFEESDAGMLLELFNAYERECTRLCEKQLLWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRVLASSVARLYAAQREEMGYPMLNTGIRKG

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=293, Percent_Identity=63.481228668942, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_DESDG (Q30ZR5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388526.1
- HSSP:   Q9WY59
- ProteinModelPortal:   Q30ZR5
- SMR:   Q30ZR5
- STRING:   Q30ZR5
- GeneID:   3757042
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2034
- NMPDR:   fig|207559.3.peg.2317
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   DDES207559:DDE_2034-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34016; Mature: 34016

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQDVILTLQNFWARRGCAIQQPFDSECGAGTFNPATFLRVIGPEPWNVAYVEPSRRPT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCEEEEECCCCCCC
DGRYGENPNRLQHYFQFQVILKPSPDNVQEIYIDSLRALGINPAEHDIRFVEDDWESPTL
CCCCCCCHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
GAWGLGWEVWLNGMEVTQFTYFQQVGGIDLSPTSVEITYGLERLCMYLQEKESVYDLMWN
CCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCC
DTVTYGHIYHRNEVEMSRYNFEESDAGMLLELFNAYERECTRLCEKQLLWPAYDYCLKCS
CCEEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
HTFNLLDARGAISITERTGYIGRVRVLASSVARLYAAQREEMGYPMLNTGIRKG
CCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure
MNFQDVILTLQNFWARRGCAIQQPFDSECGAGTFNPATFLRVIGPEPWNVAYVEPSRRPT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCEEEEECCCCCCC
DGRYGENPNRLQHYFQFQVILKPSPDNVQEIYIDSLRALGINPAEHDIRFVEDDWESPTL
CCCCCCCHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
GAWGLGWEVWLNGMEVTQFTYFQQVGGIDLSPTSVEITYGLERLCMYLQEKESVYDLMWN
CCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCC
DTVTYGHIYHRNEVEMSRYNFEESDAGMLLELFNAYERECTRLCEKQLLWPAYDYCLKCS
CCEEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
HTFNLLDARGAISITERTGYIGRVRVLASSVARLYAAQREEMGYPMLNTGIRKG
CCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA