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The map label for this gene is degP [H]

Identifier: 78357056

GI number: 78357056

Start: 2054696

End: 2056138

Strand: Direct

Name: degP [H]

Synonym: Dde_2013

Alternate gene names: 78357056

Gene position: 2054696-2056138 (Clockwise)

Preceding gene: 78357054

Following gene: 78357057

Centisome position: 55.08

GC content: 57.24

Gene sequence:

>1443_bases
ATGAACCGATACACCAAACGCCTTCAGCTCACGTTGCTGACAACCGTATTCGCGCTGGCCGCCACCATGGCCCACGCGGC
CGGAGTTCCTGATTTCACCGCACTGTCCGCAAAAGCCGGACCGGCAGTTGTCAACATCAACACCGAAAAAAGCGTGGAAA
ACAAAATTCCCGAACAATGGAGAGAATTCTTCCAGAACAGACCCCACGGTCTGCCTTTTGATGATTTCTTCAACCAGTTC
GAGCGTTTTTTCAACCAGCCCCAGCGCCCGCGCAAACAGCGCTCGCTCGGTTCGGGCTTCATCATCTCTCCGGACGGATA
CATTGTCACCAACAACCATGTGATCGCCGGCGCCGATGTAGTTTCGGTAAACGTGGAAAGTGCCAAAGGCGAACCGGACA
CGTTTGAGGCCACTGTTGTCGGCACCGACAGCGAAACAGACCTCGCTCTGCTTAAAATCGATGCAGGCCGGCCGCTTGCC
ACCCTGCCGTTCGGTGATTCCGACGCACTTCAGGTCGGCGAATGGGTTATGGCCATCGGCAACCCCTTCGGTCTTGACCA
CTCGGTGACTGCAGGCATCATCAGCGCGCTGGGCCGCGATATCCGCTCCGGTCCATTCGACGATTTCATTCAGACTGATG
CGTCCATCAACCCCGGTAACAGCGGCGGCCCCCTCATCAACAGTGACGGCAAAGTGATAGGCATCAACACCGCCATCATA
GCCAGCGGTCAGGGCATTGGATTTGCGGTACCCAGCAACCTTGCAAGAAGGGTCATAGAAGAACTGAAGACAAACAAGCG
GGTGGCCCGCGGCTGGATAGGCGTCACCATTCAGGACATTGACGAAAATACCGCCAAGGCGCTGGGACTTAAAAACACCA
GAGGCGCGCTCATCGGCAATGTGCTCAGCGGGGAACCCGCAGACAAAGCCGGAATACGCGCGGGCGATATCATCATCAAA
GTGAACCGTAATGAGATTTCCGGTGCCTCTGACCTGTTGCGCACCATCGCCGACCTGTCCCCCGGAGACAAGGCCACAGT
GGTCGCCGTGCGCAACGGTGCGCAAAAGACCTTCACTCTCACGCTGGGCGAGAGAGGAACAGAAATGGCAGCCCGCGATG
AAACCCCGCAACAGAAGCAGAATGCCGCCACAGGTCAGCTGGGGCTCAAGCTGCGCCAGATGACAGAGCAGGAAGCCGGA
CAGCTTGGTCTCGAATCAACCAATGGACTGCTTGTGGTGGGTATCCAGCAAAATTCACCCGCCGCCATGGCAGATCTGCG
GCCCGGCGATGTGATCCTGATGGCGAATCTGAAGCCTGTGAACACCGTCGGCCAGCTGCAGAAAATTGTTGAAGGCGACG
CCGCAAAGCGCGGAGCCATCATGTTCCAGATATACCGCAGGGGTGAGACGTTTTTCCGCACGCTCTCCCTGAGTGCCGAA
TAA

Upstream 100 bases:

>100_bases
GCAGCACGGTGGTTTACAACACAAAAATAAGCTCTATTATCGTTACGTATTGCCACGGCCTCCAGTTTTGAACCAAGGCA
GGTTACAAGGAGTAACTTAT

Downstream 100 bases:

>100_bases
AGCCTGTTCACCGCCTCATCAAGGGGATGCGCCATGCGCATCCCCTTTTCTTTTCCCCTTTTGCCCTTGTCTGTGCTGTG
ACAGATGCTTACAGTTGGCA

Product: peptidase S1C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MNRYTKRLQLTLLTTVFALAATMAHAAGVPDFTALSAKAGPAVVNINTEKSVENKIPEQWREFFQNRPHGLPFDDFFNQF
ERFFNQPQRPRKQRSLGSGFIISPDGYIVTNNHVIAGADVVSVNVESAKGEPDTFEATVVGTDSETDLALLKIDAGRPLA
TLPFGDSDALQVGEWVMAIGNPFGLDHSVTAGIISALGRDIRSGPFDDFIQTDASINPGNSGGPLINSDGKVIGINTAII
ASGQGIGFAVPSNLARRVIEELKTNKRVARGWIGVTIQDIDENTAKALGLKNTRGALIGNVLSGEPADKAGIRAGDIIIK
VNRNEISGASDLLRTIADLSPGDKATVVAVRNGAQKTFTLTLGERGTEMAARDETPQQKQNAATGQLGLKLRQMTEQEAG
QLGLESTNGLLVVGIQQNSPAAMADLRPGDVILMANLKPVNTVGQLQKIVEGDAAKRGAIMFQIYRRGETFFRTLSLSAE

Sequences:

>Translated_480_residues
MNRYTKRLQLTLLTTVFALAATMAHAAGVPDFTALSAKAGPAVVNINTEKSVENKIPEQWREFFQNRPHGLPFDDFFNQF
ERFFNQPQRPRKQRSLGSGFIISPDGYIVTNNHVIAGADVVSVNVESAKGEPDTFEATVVGTDSETDLALLKIDAGRPLA
TLPFGDSDALQVGEWVMAIGNPFGLDHSVTAGIISALGRDIRSGPFDDFIQTDASINPGNSGGPLINSDGKVIGINTAII
ASGQGIGFAVPSNLARRVIEELKTNKRVARGWIGVTIQDIDENTAKALGLKNTRGALIGNVLSGEPADKAGIRAGDIIIK
VNRNEISGASDLLRTIADLSPGDKATVVAVRNGAQKTFTLTLGERGTEMAARDETPQQKQNAATGQLGLKLRQMTEQEAG
QLGLESTNGLLVVGIQQNSPAAMADLRPGDVILMANLKPVNTVGQLQKIVEGDAAKRGAIMFQIYRRGETFFRTLSLSAE
>Mature_480_residues
MNRYTKRLQLTLLTTVFALAATMAHAAGVPDFTALSAKAGPAVVNINTEKSVENKIPEQWREFFQNRPHGLPFDDFFNQF
ERFFNQPQRPRKQRSLGSGFIISPDGYIVTNNHVIAGADVVSVNVESAKGEPDTFEATVVGTDSETDLALLKIDAGRPLA
TLPFGDSDALQVGEWVMAIGNPFGLDHSVTAGIISALGRDIRSGPFDDFIQTDASINPGNSGGPLINSDGKVIGINTAII
ASGQGIGFAVPSNLARRVIEELKTNKRVARGWIGVTIQDIDENTAKALGLKNTRGALIGNVLSGEPADKAGIRAGDIIIK
VNRNEISGASDLLRTIADLSPGDKATVVAVRNGAQKTFTLTLGERGTEMAARDETPQQKQNAATGQLGLKLRQMTEQEAG
QLGLESTNGLLVVGIQQNSPAAMADLRPGDVILMANLKPVNTVGQLQKIVEGDAAKRGAIMFQIYRRGETFFRTLSLSAE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=286, Percent_Identity=36.3636363636364, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7019477, Length=288, Percent_Identity=36.8055555555556, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI22129776, Length=280, Percent_Identity=37.8571428571429, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI24308541, Length=255, Percent_Identity=32.9411764705882, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1789629, Length=489, Percent_Identity=34.560327198364, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1786356, Length=473, Percent_Identity=34.46088794926, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789630, Length=296, Percent_Identity=39.527027027027, Blast_Score=185, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24646839, Length=310, Percent_Identity=34.8387096774194, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 51255; Mature: 51255

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYTKRLQLTLLTTVFALAATMAHAAGVPDFTALSAKAGPAVVNINTEKSVENKIPEQW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECCHHHHHHCCHHHH
REFFQNRPHGLPFDDFFNQFERFFNQPQRPRKQRSLGSGFIISPDGYIVTNNHVIAGADV
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCEEECCCCEEEECCEEEECCEE
VSVNVESAKGEPDTFEATVVGTDSETDLALLKIDAGRPLATLPFGDSDALQVGEWVMAIG
EEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHHCCC
NPFGLDHSVTAGIISALGRDIRSGPFDDFIQTDASINPGNSGGPLINSDGKVIGINTAII
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEECCCCCEEEEEEEEE
ASGQGIGFAVPSNLARRVIEELKTNKRVARGWIGVTIQDIDENTAKALGLKNTRGALIGN
ECCCCCEEECCHHHHHHHHHHHHHCHHHHCCEEEEEEEECCCCHHHHCCCCCCCCHHEEH
VLSGEPADKAGIRAGDIIIKVNRNEISGASDLLRTIADLSPGDKATVVAVRNGAQKTFTL
HHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
TLGERGTEMAARDETPQQKQNAATGQLGLKLRQMTEQEAGQLGLESTNGLLVVGIQQNSP
EECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
AAMADLRPGDVILMANLKPVNTVGQLQKIVEGDAAKRGAIMFQIYRRGETFFRTLSLSAE
CCEECCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCC
>Mature Secondary Structure
MNRYTKRLQLTLLTTVFALAATMAHAAGVPDFTALSAKAGPAVVNINTEKSVENKIPEQW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECCHHHHHHCCHHHH
REFFQNRPHGLPFDDFFNQFERFFNQPQRPRKQRSLGSGFIISPDGYIVTNNHVIAGADV
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCEEECCCCEEEECCEEEECCEE
VSVNVESAKGEPDTFEATVVGTDSETDLALLKIDAGRPLATLPFGDSDALQVGEWVMAIG
EEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHHCCC
NPFGLDHSVTAGIISALGRDIRSGPFDDFIQTDASINPGNSGGPLINSDGKVIGINTAII
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEECCCCCEEEEEEEEE
ASGQGIGFAVPSNLARRVIEELKTNKRVARGWIGVTIQDIDENTAKALGLKNTRGALIGN
ECCCCCEEECCHHHHHHHHHHHHHCHHHHCCEEEEEEEECCCCHHHHCCCCCCCCHHEEH
VLSGEPADKAGIRAGDIIIKVNRNEISGASDLLRTIADLSPGDKATVVAVRNGAQKTFTL
HHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
TLGERGTEMAARDETPQQKQNAATGQLGLKLRQMTEQEAGQLGLESTNGLLVVGIQQNSP
EECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
AAMADLRPGDVILMANLKPVNTVGQLQKIVEGDAAKRGAIMFQIYRRGETFFRTLSLSAE
CCEECCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]