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The map label for this gene is yrbG [H]

Identifier: 78356897

GI number: 78356897

Start: 1903655

End: 1904623

Strand: Reverse

Name: yrbG [H]

Synonym: Dde_1854

Alternate gene names: 78356897

Gene position: 1904623-1903655 (Counterclockwise)

Preceding gene: 78356898

Following gene: 78356896

Centisome position: 51.06

GC content: 62.23

Gene sequence:

>969_bases
ATGACACTCGCCTTTGTTGCTGTGATTTTTGGCCTGGCGCTGCTGGTCTGGAGCGCCGACCGTTTTGTGGAGGGATCTGC
CTCCACCGCCCGTCATTTCGGCATGCCGCCGCTGTTGATCGGCATGGTGATCGTGGGTTTCGGCACCTCCGCGCCGGAGA
TGGTGGTGTCGGCACTGGCCGCCTCGCAGGGCAATCCGGGCATCGCGCTGGGCAACGCCTACGGGTCGAACATCACCAAC
ATCGCCCTGATCCTGGGGGTGACCGCACTGATCAGCCCTATAGCCGTCCATTCGCAGGTGCTGCGCAAAGAGCTGCCCAT
CCTCACGGTGGTGACTGCACTGGCGGCCTGGCAACTCTGGGATGGCAAAATAACCCGGCTTGATGCCATCGTGTTGCTGA
CCGTGTTCGGCGGCCTGATGGCCTGGACCATCTGGCAGGGTATGCAGAAAAAAGCCGATGCGCTGGGGAGCGAGATGGAG
CAGGAACTCGACGTTCGCGCCATGCCCATTCGCCGTGCGGTCTTCTGGCTGTCAGTGGGCCTGGTGCTGCTCGTCGTCAG
CTCCCGCATCCTGGTCTGGGGCGCGGTGGAGATCGCTCATGGATTCGGGGTCAGCGACCTGATCATCGGCTTGACCATCG
TCGCGGTGGGCACCTCGCTGCCGGAACTGGCCTCGTCGATTATCGCCACCCGCAAGGGGGAACATGACATCGCGCTGGGC
AACGTTCTTGGGTCCAACCTGTTCAACACCCTGGCGGTGGTGGGGATCGCCGGTGCGATTCACCCGATGGCGATCGGACC
GGAAGTTTTCAACCGCGACATGATGGTGATGGCTGGGCTGACCCTTTCGCTCTTCGTGTTCGGCTACGGATTCCGTGGAC
CGGGACGTATCAACCGCCTTGAAGGCGCGGTGCTGCTGGCCTGTTACGTGGGCTATACGGCCTACCTGATCACAACGATT
CTGGCATGA

Upstream 100 bases:

>100_bases
TGAAACAGAAAATGATCGAATGGTACAGCCTTTTGCGGGACATGGTCATGGGGCTGTTCAAGAGCCTCACTGGGCAAACT
GATATGAAAAGGGGAGTGGC

Downstream 100 bases:

>100_bases
AGGGCAGGTCGGTGAGCGTAAAAGGGCTGGACCCCTCGCAGCAGTCTACCAAAAGGGCGATTTCGGTCCGCTGGACGGCT
TACGCTTTCCTGTTTCTTGC

Product: K+-dependent Na+/Ca+ exchanger-like protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTLAFVAVIFGLALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITN
IALILGVTALISPIAVHSQVLRKELPILTVVTALAAWQLWDGKITRLDAIVLLTVFGGLMAWTIWQGMQKKADALGSEME
QELDVRAMPIRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALG
NVLGSNLFNTLAVVGIAGAIHPMAIGPEVFNRDMMVMAGLTLSLFVFGYGFRGPGRINRLEGAVLLACYVGYTAYLITTI
LA

Sequences:

>Translated_322_residues
MTLAFVAVIFGLALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITN
IALILGVTALISPIAVHSQVLRKELPILTVVTALAAWQLWDGKITRLDAIVLLTVFGGLMAWTIWQGMQKKADALGSEME
QELDVRAMPIRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALG
NVLGSNLFNTLAVVGIAGAIHPMAIGPEVFNRDMMVMAGLTLSLFVFGYGFRGPGRINRLEGAVLLACYVGYTAYLITTI
LA
>Mature_321_residues
TLAFVAVIFGLALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITNI
ALILGVTALISPIAVHSQVLRKELPILTVVTALAAWQLWDGKITRLDAIVLLTVFGGLMAWTIWQGMQKKADALGSEMEQ
ELDVRAMPIRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALGN
VLGSNLFNTLAVVGIAGAIHPMAIGPEVFNRDMMVMAGLTLSLFVFGYGFRGPGRINRLEGAVLLACYVGYTAYLITTIL
A

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=265, Percent_Identity=42.6415094339623, Blast_Score=182, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI193208990, Length=104, Percent_Identity=40.3846153846154, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33939; Mature: 33808

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAFVAVIFGLALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ASQGNPGIALGNAYGSNITNIALILGVTALISPIAVHSQVLRKELPILTVVTALAAWQLW
HCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
DGKITRLDAIVLLTVFGGLMAWTIWQGMQKKADALGSEMEQELDVRAMPIRRAVFWLSVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALG
HHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
NVLGSNLFNTLAVVGIAGAIHPMAIGPEVFNRDMMVMAGLTLSLFVFGYGFRGPGRINRL
HHHHHHHHHHHHHHHHHHHHCCHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
EGAVLLACYVGYTAYLITTILA
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLAFVAVIFGLALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ASQGNPGIALGNAYGSNITNIALILGVTALISPIAVHSQVLRKELPILTVVTALAAWQLW
HCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
DGKITRLDAIVLLTVFGGLMAWTIWQGMQKKADALGSEMEQELDVRAMPIRRAVFWLSVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALG
HHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
NVLGSNLFNTLAVVGIAGAIHPMAIGPEVFNRDMMVMAGLTLSLFVFGYGFRGPGRINRL
HHHHHHHHHHHHHHHHHHHHCCHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
EGAVLLACYVGYTAYLITTILA
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]