Click here to switch to the map view.

The map label for this gene is gidA

Identifier: 78356852

GI number: 78356852

Start: 1858079

End: 1859965

Strand: Reverse

Name: gidA

Synonym: Dde_1809

Alternate gene names: 78356852

Gene position: 1859965-1858079 (Counterclockwise)

Preceding gene: 78356853

Following gene: 78356851

Centisome position: 49.86

GC content: 58.08

Gene sequence:

>1887_bases
ATGTCAGTAAAAAAAGCTTCTTTTCCCGAACTGTTCGATCTTGTGGTGGTGGGTGCCGGCCATGCCGGATGTGAAGCCGC
CATGGCTTCTGCCCGTCTGGGGCTTAAAACGCTGCTGCTGACCATCAACGCGGACAGAATCGGCCATTTGTCATGCAACC
CTGCCATAGGCGGGCTGGCAAAAGGGCATATGGTCAAGGAAATTGACGCCCTGGGCGGCATGATGGGACTGTGGGCCGAC
GAAGCCGGCATCCAGTTTCGTCTGCTGAATACAAGCAAGGGGCCTGCCGTCCATTCCACACGGGCCCAGATAGACCGCGA
TGCTTACATGAAAGCCGTGCAGCGGGATGTTTTCCGGCAGGATAATTTGTGGGTGTGGCAGGATACCGCGGAAAACGTGC
TGGTGGAAAACGGCCGCGCCGCCGGGGTGTCCACTCTGCTCGGTCAGGAGTTCAGGTCGCGGGCGGTCTGCGTCACCGCC
GGAACATTCATGAGCGGGCTTATCCACGTGGGGTTGACCCACTTTTCCGGTGGCCGGCTGGGTGACCCTGCCGCACAGGG
ACTTTCCGCAAGCCTGCGTGCCGTCGGACTGGAACTGGGCCGTCTGAAAACCGGCACCACCCCCCGCCTGCTACGTGACA
GCATCAATTTTGATGTCATGGTGGAGCAGCCCGGCGATAATCCGCCGCGCCCTTTCAGCTTCCGGTCTCGGCATGCACGC
ATGCCGCAGGTGCCGTGCTATCTTACGTGGACCAACGAGGCGACGCATGAGGCTATACGGGCAGGTTTTGATCGTTCCCC
CATGTTCACCGGCATCATTTCCGGTACCGGAGCGCGCTACTGCCCTTCCATAGAAGACAAGATCGCGCGTTTTCCCGACA
AGGACAGGCATCAGATTTTTATCGAGCCGGAAGGCCTGCACAGTCCGGAAGTTTACCCCGGTGGAATTCCTACCAGCCTG
CCGCTGGACGTGCAGAAAGCCATGATAGCCACCATTCCCGGTCTGGAAAAGGCCCAGATTGTGCGGCCCGGCTATGCCAT
AGAATATGATTATGCCAATCCCACGCAGCTTAAGCCCACACTTGAAACAAAAGTTCTGCCGGGATTGTGGATGGCCGGAC
AGGTCAACGGCACCTCCGGCTATGAGGAAGCCGCCGCTCAGGGGCTGTGGGCCGCTCTGAACATTTTCTGCGGTCTGCGC
GGTCTGCCTGCTTTTATTCCGGGCCGTGATGAGGCGTATATGGCAGTGCTGGTGGATGACCTTGTGACCAAGGGAACGCT
GGAGCCGTACCGCATGTTTACGTCGCGCGCAGAGCACAGGCTTCTGCTGCGGGAAAATAATGCCGACAGCAGACTGACAC
CCGCGGGTCGCAGTCTGGGGTTGGTTGATGACGCCCAGTGGCAGCTGTACACCGCCAAAAAAACGGCGCTGGAGCAACTG
CTTGCGGAGCTTGACGCAAGACAGGTCAGGCCCGATGCCGCAACCCGGGATATTTTTGTGCATATGAATGAGGCGGTGCC
CACCAGATCGGTGAGTCTGGCAGACCTTTTGCGCAGACCGGCACTGGGCATCACGGACCTGCAGGCGTTCGGCCTTGAAA
CGGACGGTTTTGCCGCGGATGTTCTTGAAGAGGCCCAGACCATTGTAAAATATTCCGGGTATCTGAAGCGGCAGGAAGAG
TTGGTGCTGCGTACTGCGCGACATGAATCTGTGGTCATTTCCGAAGCGGCGGATTATGCCGCTGTTCACGGATTGACTCG
GGAAGCTGTTGAAAAACTGAGTAAAGTCCGTCCACGGACCCTTGGTCAGGCTGCGCGTATTTCCGGAATCACACCCGCTG
CATTATCGTGCATAGAGGTCTATCTGAAAAAAAACGGCTGGCTGTAA

Upstream 100 bases:

>100_bases
CGGCCAATATAGGCGACGCAAAAGTGATGCTTCATGTCGCCCTTGCTCCGGCCCGATAAAAGTCAGCCCGGCGCGTCGAA
ATGACGCGCCTTTTTTAGCT

Downstream 100 bases:

>100_bases
CATTATTATGGTGTTTTTTTTGCATTGTTCAGCGGATACTGCCGTTGGTACAATGCCCTTGAAATACACAAGGCTGTTTT
CAGCCTTTGGAGCAGCTTTT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSVKKASFPELFDLVVVGAGHAGCEAAMASARLGLKTLLLTINADRIGHLSCNPAIGGLAKGHMVKEIDALGGMMGLWAD
EAGIQFRLLNTSKGPAVHSTRAQIDRDAYMKAVQRDVFRQDNLWVWQDTAENVLVENGRAAGVSTLLGQEFRSRAVCVTA
GTFMSGLIHVGLTHFSGGRLGDPAAQGLSASLRAVGLELGRLKTGTTPRLLRDSINFDVMVEQPGDNPPRPFSFRSRHAR
MPQVPCYLTWTNEATHEAIRAGFDRSPMFTGIISGTGARYCPSIEDKIARFPDKDRHQIFIEPEGLHSPEVYPGGIPTSL
PLDVQKAMIATIPGLEKAQIVRPGYAIEYDYANPTQLKPTLETKVLPGLWMAGQVNGTSGYEEAAAQGLWAALNIFCGLR
GLPAFIPGRDEAYMAVLVDDLVTKGTLEPYRMFTSRAEHRLLLRENNADSRLTPAGRSLGLVDDAQWQLYTAKKTALEQL
LAELDARQVRPDAATRDIFVHMNEAVPTRSVSLADLLRRPALGITDLQAFGLETDGFAADVLEEAQTIVKYSGYLKRQEE
LVLRTARHESVVISEAADYAAVHGLTREAVEKLSKVRPRTLGQAARISGITPAALSCIEVYLKKNGWL

Sequences:

>Translated_628_residues
MSVKKASFPELFDLVVVGAGHAGCEAAMASARLGLKTLLLTINADRIGHLSCNPAIGGLAKGHMVKEIDALGGMMGLWAD
EAGIQFRLLNTSKGPAVHSTRAQIDRDAYMKAVQRDVFRQDNLWVWQDTAENVLVENGRAAGVSTLLGQEFRSRAVCVTA
GTFMSGLIHVGLTHFSGGRLGDPAAQGLSASLRAVGLELGRLKTGTTPRLLRDSINFDVMVEQPGDNPPRPFSFRSRHAR
MPQVPCYLTWTNEATHEAIRAGFDRSPMFTGIISGTGARYCPSIEDKIARFPDKDRHQIFIEPEGLHSPEVYPGGIPTSL
PLDVQKAMIATIPGLEKAQIVRPGYAIEYDYANPTQLKPTLETKVLPGLWMAGQVNGTSGYEEAAAQGLWAALNIFCGLR
GLPAFIPGRDEAYMAVLVDDLVTKGTLEPYRMFTSRAEHRLLLRENNADSRLTPAGRSLGLVDDAQWQLYTAKKTALEQL
LAELDARQVRPDAATRDIFVHMNEAVPTRSVSLADLLRRPALGITDLQAFGLETDGFAADVLEEAQTIVKYSGYLKRQEE
LVLRTARHESVVISEAADYAAVHGLTREAVEKLSKVRPRTLGQAARISGITPAALSCIEVYLKKNGWL
>Mature_627_residues
SVKKASFPELFDLVVVGAGHAGCEAAMASARLGLKTLLLTINADRIGHLSCNPAIGGLAKGHMVKEIDALGGMMGLWADE
AGIQFRLLNTSKGPAVHSTRAQIDRDAYMKAVQRDVFRQDNLWVWQDTAENVLVENGRAAGVSTLLGQEFRSRAVCVTAG
TFMSGLIHVGLTHFSGGRLGDPAAQGLSASLRAVGLELGRLKTGTTPRLLRDSINFDVMVEQPGDNPPRPFSFRSRHARM
PQVPCYLTWTNEATHEAIRAGFDRSPMFTGIISGTGARYCPSIEDKIARFPDKDRHQIFIEPEGLHSPEVYPGGIPTSLP
LDVQKAMIATIPGLEKAQIVRPGYAIEYDYANPTQLKPTLETKVLPGLWMAGQVNGTSGYEEAAAQGLWAALNIFCGLRG
LPAFIPGRDEAYMAVLVDDLVTKGTLEPYRMFTSRAEHRLLLRENNADSRLTPAGRSLGLVDDAQWQLYTAKKTALEQLL
AELDARQVRPDAATRDIFVHMNEAVPTRSVSLADLLRRPALGITDLQAFGLETDGFAADVLEEAQTIVKYSGYLKRQEEL
VLRTARHESVVISEAADYAAVHGLTREAVEKLSKVRPRTLGQAARISGITPAALSCIEVYLKKNGWL

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=639, Percent_Identity=38.6541471048513, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI19882217, Length=664, Percent_Identity=37.1987951807229, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI183227703, Length=679, Percent_Identity=36.3770250368188, Blast_Score=410, Evalue=1e-114,
Organism=Escherichia coli, GI2367273, Length=627, Percent_Identity=52.4720893141946, Blast_Score=643, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=632, Percent_Identity=38.7658227848101, Blast_Score=452, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321202, Length=644, Percent_Identity=40.2173913043478, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24658174, Length=632, Percent_Identity=41.2974683544304, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_DESDG (Q310P0)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388301.1
- ProteinModelPortal:   Q310P0
- SMR:   Q310P0
- STRING:   Q310P0
- GeneID:   3756812
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1809
- NMPDR:   fig|207559.3.peg.1120
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   DDES207559:DDE_1809-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 68417; Mature: 68286

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKKASFPELFDLVVVGAGHAGCEAAMASARLGLKTLLLTINADRIGHLSCNPAIGGLA
CCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHCEEEEEEEECCCCCCCEECCCCCCCCC
KGHMVKEIDALGGMMGLWADEAGIQFRLLNTSKGPAVHSTRAQIDRDAYMKAVQRDVFRQ
CCHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DNLWVWQDTAENVLVENGRAAGVSTLLGQEFRSRAVCVTAGTFMSGLIHVGLTHFSGGRL
CCEEEECCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCC
GDPAAQGLSASLRAVGLELGRLKTGTTPRLLRDSINFDVMVEQPGDNPPRPFSFRSRHAR
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCHHCCC
MPQVPCYLTWTNEATHEAIRAGFDRSPMFTGIISGTGARYCPSIEDKIARFPDKDRHQIF
CCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEE
IEPEGLHSPEVYPGGIPTSLPLDVQKAMIATIPGLEKAQIVRPGYAIEYDYANPTQLKPT
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCCCC
LETKVLPGLWMAGQVNGTSGYEEAAAQGLWAALNIFCGLRGLPAFIPGRDEAYMAVLVDD
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LVTKGTLEPYRMFTSRAEHRLLLRENNADSRLTPAGRSLGLVDDAQWQLYTAKKTALEQL
HHHCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
LAELDARQVRPDAATRDIFVHMNEAVPTRSVSLADLLRRPALGITDLQAFGLETDGFAAD
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCCCCHHHH
VLEEAQTIVKYSGYLKRQEELVLRTARHESVVISEAADYAAVHGLTREAVEKLSKVRPRT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHH
LGQAARISGITPAALSCIEVYLKKNGWL
HCCHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVKKASFPELFDLVVVGAGHAGCEAAMASARLGLKTLLLTINADRIGHLSCNPAIGGLA
CCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHCEEEEEEEECCCCCCCEECCCCCCCCC
KGHMVKEIDALGGMMGLWADEAGIQFRLLNTSKGPAVHSTRAQIDRDAYMKAVQRDVFRQ
CCHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DNLWVWQDTAENVLVENGRAAGVSTLLGQEFRSRAVCVTAGTFMSGLIHVGLTHFSGGRL
CCEEEECCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCC
GDPAAQGLSASLRAVGLELGRLKTGTTPRLLRDSINFDVMVEQPGDNPPRPFSFRSRHAR
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCHHCCC
MPQVPCYLTWTNEATHEAIRAGFDRSPMFTGIISGTGARYCPSIEDKIARFPDKDRHQIF
CCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEE
IEPEGLHSPEVYPGGIPTSLPLDVQKAMIATIPGLEKAQIVRPGYAIEYDYANPTQLKPT
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCCCC
LETKVLPGLWMAGQVNGTSGYEEAAAQGLWAALNIFCGLRGLPAFIPGRDEAYMAVLVDD
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LVTKGTLEPYRMFTSRAEHRLLLRENNADSRLTPAGRSLGLVDDAQWQLYTAKKTALEQL
HHHCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
LAELDARQVRPDAATRDIFVHMNEAVPTRSVSLADLLRRPALGITDLQAFGLETDGFAAD
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCCCCHHHH
VLEEAQTIVKYSGYLKRQEELVLRTARHESVVISEAADYAAVHGLTREAVEKLSKVRPRT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHH
LGQAARISGITPAALSCIEVYLKKNGWL
HCCHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA