Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 78356850

GI number: 78356850

Start: 1855939

End: 1856835

Strand: Reverse

Name: corC [H]

Synonym: Dde_1807

Alternate gene names: 78356850

Gene position: 1856835-1855939 (Counterclockwise)

Preceding gene: 78356851

Following gene: 78356849

Centisome position: 49.78

GC content: 51.17

Gene sequence:

>897_bases
ATGCTTATTCGAAAAGGAACAGGTATCCGGACCCGCTGCCCAGCAGAATCGGAAGACATTTTAACAGGAGTGAAAACATT
GGACGGAGGCTCGGACAGTAGGCTCTGGTCGCTTTTTTCAAGATTCTTTTCCGCAAAGAACGGCGACAGTGTTGAACAGG
CCATCATTGAAGCTCAGGATGACGGTGAACTGGATTCTGAAGAAAGCACCATGCTTCTCAGCATCCTGCGGCTGGATGAA
ATGCAGGTCTATGAGATCATGACTCCCAGAACCGACATTGACTGTGCGGACGACCAAAGCTCTCTCGGGGACATCATCGA
TCTGATTGTTTCTTCGGGACATTCACGCATTCCCGTTTATCGTGACAACCGCGACAACATCATCGGCGTTGTTTATGCCA
AAGACCTGCTCAGTGTCCTTACCGACACCGGTCAGCGCAGTGCGCCGGTGACTGAAACCATGCGTCAGCCCATCTTTGTT
CCGGAAACGAAAAAGGTGAGCGAGCTTCTGCAGGAATTCCGGACCCGCAAGAATCATCTTGCCATTGCGCTTGATGAATA
CGGCGGCACCTCCGGTCTTGTGACCATTGAGGATGTGCTGGAAGTAATTGTGGGCGACATAGAAGACGAGCATGATGCGC
CCCGTCAGGAAGATATACGTGCTCTTGACGACGGAACGCTTGAAGTTTCAGGCAGGGCTTTCCTTGAAGATCTGTCAGAA
CGGCTCGGAGTTTTGCTCGAGTCCGATCAGGTGGAAACAATCGGCGGTTATCTCTCTGAAATAGCAGGGCATGTCCCGCA
GGCAGGAGAATCTTTTACTGTCGGCGCTCACAGCTATACGGTAATGGAAGCTGACGCCAAGCAGATAAAGACAATCCGTG
TTACTCCCTCTGAATAA

Upstream 100 bases:

>100_bases
ACTGGGCCATGAAGCGCCATCTGGAGCTTTACCGCGAAAGGGGCCCGGAAGAGTAAGAGTCATTTTTTAGCCGGTAAACC
GCTTGCCTTGAAAAGCGGTT

Downstream 100 bases:

>100_bases
TTCAAGGCGGCTCCGGCCGCCTTTTTCATGATGACACACCGTTATGACCATGCGTGCGAGATTTGCAGTGAATAACAGGT
CAATCGTTCTTATTGTTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLIRKGTGIRTRCPAESEDILTGVKTLDGGSDSRLWSLFSRFFSAKNGDSVEQAIIEAQDDGELDSEESTMLLSILRLDE
MQVYEIMTPRTDIDCADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMRQPIFV
PETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPRQEDIRALDDGTLEVSGRAFLEDLSE
RLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVGAHSYTVMEADAKQIKTIRVTPSE

Sequences:

>Translated_298_residues
MLIRKGTGIRTRCPAESEDILTGVKTLDGGSDSRLWSLFSRFFSAKNGDSVEQAIIEAQDDGELDSEESTMLLSILRLDE
MQVYEIMTPRTDIDCADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMRQPIFV
PETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPRQEDIRALDDGTLEVSGRAFLEDLSE
RLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVGAHSYTVMEADAKQIKTIRVTPSE
>Mature_298_residues
MLIRKGTGIRTRCPAESEDILTGVKTLDGGSDSRLWSLFSRFFSAKNGDSVEQAIIEAQDDGELDSEESTMLLSILRLDE
MQVYEIMTPRTDIDCADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMRQPIFV
PETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPRQEDIRALDDGTLEVSGRAFLEDLSE
RLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVGAHSYTVMEADAKQIKTIRVTPSE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=30.5825242718447, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI94681046, Length=166, Percent_Identity=33.7349397590361, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40068049, Length=141, Percent_Identity=34.7517730496454, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40068055, Length=162, Percent_Identity=32.0987654320988, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI40068053, Length=162, Percent_Identity=32.0987654320988, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1786879, Length=259, Percent_Identity=35.9073359073359, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI87082033, Length=284, Percent_Identity=28.5211267605634, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693175, Length=230, Percent_Identity=29.5652173913043, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=32.9113924050633, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790664, Length=248, Percent_Identity=26.6129032258064, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32793; Mature: 32793

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRKGTGIRTRCPAESEDILTGVKTLDGGSDSRLWSLFSRFFSAKNGDSVEQAIIEAQD
CEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
DGELDSEESTMLLSILRLDEMQVYEIMTPRTDIDCADDQSSLGDIIDLIVSSGHSRIPVY
CCCCCCCHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
RDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMRQPIFVPETKKVSELLQEFRTRKNHL
ECCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCE
AIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPRQEDIRALDDGTLEVSGRAFLEDLSE
EEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHH
RLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVGAHSYTVMEADAKQIKTIRVTPSE
HHCEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCHHHEEEEEECCCC
>Mature Secondary Structure
MLIRKGTGIRTRCPAESEDILTGVKTLDGGSDSRLWSLFSRFFSAKNGDSVEQAIIEAQD
CEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
DGELDSEESTMLLSILRLDEMQVYEIMTPRTDIDCADDQSSLGDIIDLIVSSGHSRIPVY
CCCCCCCHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
RDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMRQPIFVPETKKVSELLQEFRTRKNHL
ECCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCE
AIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPRQEDIRALDDGTLEVSGRAFLEDLSE
EEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHH
RLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVGAHSYTVMEADAKQIKTIRVTPSE
HHCEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]