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The map label for this gene is dtd [H]

Identifier: 78356767

GI number: 78356767

Start: 1781558

End: 1782070

Strand: Reverse

Name: dtd [H]

Synonym: Dde_1724

Alternate gene names: 78356767

Gene position: 1782070-1781558 (Counterclockwise)

Preceding gene: 78356768

Following gene: 78356766

Centisome position: 47.77

GC content: 55.56

Gene sequence:

>513_bases
ATGAAACTGCTTCTTCAACGTGTAAATCAGGCCAGTGTTACTGTTGATAACGAGGTGATCGGCGAAATCCAGTGCGGCCT
GCTGGTTCTTGCGGGCTTCGGAGTACAGGATCACCCCGCCCTGCCCGAAACGGACATGTGGAGTGCACTGATCCGTAAAA
TGCTTGACTTGCGCATCTTCCCTGACGGGCAAGGCAAAATGAACCTCGGTCTGCGTGACTATGGCGGCGAGTTGCTTCTG
GTGCCGCAATTCACGCTATATGCCGATTGCCGCAAAGGCAAAAGGCCGTCCTTTACCGATGCAGCGCCCCCTGAGGTGGC
ACAAAAACTTTTTGACCGGCTGGTGTGCGATGCGCAGACCCTGCTGCAAAAAAAAGTAAGCACCGGTCGGTTTGGTGCGG
AAATGTATGTGCAGCTTACCAACTGGGGGCCGGTAACCATCGAACTTTGCGGAAACGCCCCCGGGGGACAGAACAGCCAT
GCCCGACAGCAGCTCCATCCTGATCGTCGATGA

Upstream 100 bases:

>100_bases
AATTGCCCAAGACGATTGTGGGCAAGGTGCTGCGCCGCGCTTTGCGCGCCGAGGAAGAAGAAAAGCTTCGGAAAAAGAAA
AACACGAAAAGTGATGATCA

Downstream 100 bases:

>100_bases
TTCGCGTTCTGTCCGCAATGCGCTGGCTTCGCTGCTCAGAAAGAGCCATGCCATAGAACAGGCGGAAAACGGGGAACAGG
CGCTTGCGTCCTATGCGCGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKLLLQRVNQASVTVDNEVIGEIQCGLLVLAGFGVQDHPALPETDMWSALIRKMLDLRIFPDGQGKMNLGLRDYGGELLL
VPQFTLYADCRKGKRPSFTDAAPPEVAQKLFDRLVCDAQTLLQKKVSTGRFGAEMYVQLTNWGPVTIELCGNAPGGQNSH
ARQQLHPDRR

Sequences:

>Translated_170_residues
MKLLLQRVNQASVTVDNEVIGEIQCGLLVLAGFGVQDHPALPETDMWSALIRKMLDLRIFPDGQGKMNLGLRDYGGELLL
VPQFTLYADCRKGKRPSFTDAAPPEVAQKLFDRLVCDAQTLLQKKVSTGRFGAEMYVQLTNWGPVTIELCGNAPGGQNSH
ARQQLHPDRR
>Mature_170_residues
MKLLLQRVNQASVTVDNEVIGEIQCGLLVLAGFGVQDHPALPETDMWSALIRKMLDLRIFPDGQGKMNLGLRDYGGELLL
VPQFTLYADCRKGKRPSFTDAAPPEVAQKLFDRLVCDAQTLLQKKVSTGRFGAEMYVQLTNWGPVTIELCGNAPGGQNSH
ARQQLHPDRR

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=165, Percent_Identity=38.7878787878788, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1790320, Length=151, Percent_Identity=46.3576158940397, Blast_Score=118, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=38.6666666666667, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=40.3973509933775, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281361569, Length=153, Percent_Identity=39.8692810457516, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 18846; Mature: 18846

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLQRVNQASVTVDNEVIGEIQCGLLVLAGFGVQDHPALPETDMWSALIRKMLDLRIF
CCHHHHHCCCCCEEECHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PDGQGKMNLGLRDYGGELLLVPQFTLYADCRKGKRPSFTDAAPPEVAQKLFDRLVCDAQT
CCCCCCEECCEECCCCCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLQKKVSTGRFGAEMYVQLTNWGPVTIELCGNAPGGQNSHARQQLHPDRR
HHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MKLLLQRVNQASVTVDNEVIGEIQCGLLVLAGFGVQDHPALPETDMWSALIRKMLDLRIF
CCHHHHHCCCCCEEECHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PDGQGKMNLGLRDYGGELLLVPQFTLYADCRKGKRPSFTDAAPPEVAQKLFDRLVCDAQT
CCCCCCEECCEECCCCCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLQKKVSTGRFGAEMYVQLTNWGPVTIELCGNAPGGQNSHARQQLHPDRR
HHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA