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The map label for this gene is uxuR [H]

Identifier: 78356657

GI number: 78356657

Start: 1662089

End: 1662763

Strand: Direct

Name: uxuR [H]

Synonym: Dde_1614

Alternate gene names: 78356657

Gene position: 1662089-1662763 (Clockwise)

Preceding gene: 78356656

Following gene: 78356658

Centisome position: 44.56

GC content: 63.7

Gene sequence:

>675_bases
GTGCAGAGAGCAGCATATCAGGTTGCCGAAGAGATTCTGAAACTGGTCAGCAACAGCGCTGTCAGGCCCGGAGAAAGACT
GCCGGGTGAACGCGCACTGGCTGAGAGGCTGGGCTGCAGCAGAAACACCGTGCGTGAGGCGCTGGCGGCACTGTCGGCAA
GAGGTCTGGTGGAAATCCGCATGCGCAGCGGTGCCTACCTGTGCAGGCAGAACCACCCGTCACCGGACGGCGGGCGGACC
GGACCCGGCGAAGCTCTGGACGCGCTGGTCACTCTTGGTCCGGCTCTTGTGGAGCGCGTGTGCCGGGTTGCAGGCGTGTC
TGAACATGAACATGCGGAGCGTATCACGGCCCGGCTGGGCAGGGCTCTGGTAGACCGCAGCCCGCTGGATGCGTGGCGGG
GGCTGACGGCATTTTACAGCGCACTGGCTGAAATAACGGGAAACAGTCTGCTGTGCGCGGCCATGGGCAGTATTGCCCGC
TCCGGCGCGGCAGGCGGGTTTGAGAATCTGCCGGAACTGGCTCCTGCGGCCTTGCAGCAGTTTTTTGCAGAGCATGTGGA
AATGCTGCAGGCCATGCGCCGGCACGATGTGGCTCTGGCATCCCGGTGCGCGGCAGGCAGCCTTGACGCATTTGGCAGAA
TGCTGTGGCAGAAAAACGGCGGAGAGCGGAACTGA

Upstream 100 bases:

>100_bases
TTTTTTGTGGTTTTTCCTTGTTGTCAGCGAATGATCACAGACGTAGCTTTCAATCAACAACATGACGACAGAACAACAAA
AAGAATTGGTGGGACCAGAG

Downstream 100 bases:

>100_bases
TGATGACGCGCAGAAAATTTTTGCGGTTCTGGAAGGGCACAGCCGCCCCTCCTGCCGCAACAGGGTCTGCAGATGGCGGA
ACAGCGCAGGATGCGGATGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MQRAAYQVAEEILKLVSNSAVRPGERLPGERALAERLGCSRNTVREALAALSARGLVEIRMRSGAYLCRQNHPSPDGGRT
GPGEALDALVTLGPALVERVCRVAGVSEHEHAERITARLGRALVDRSPLDAWRGLTAFYSALAEITGNSLLCAAMGSIAR
SGAAGGFENLPELAPAALQQFFAEHVEMLQAMRRHDVALASRCAAGSLDAFGRMLWQKNGGERN

Sequences:

>Translated_224_residues
MQRAAYQVAEEILKLVSNSAVRPGERLPGERALAERLGCSRNTVREALAALSARGLVEIRMRSGAYLCRQNHPSPDGGRT
GPGEALDALVTLGPALVERVCRVAGVSEHEHAERITARLGRALVDRSPLDAWRGLTAFYSALAEITGNSLLCAAMGSIAR
SGAAGGFENLPELAPAALQQFFAEHVEMLQAMRRHDVALASRCAAGSLDAFGRMLWQKNGGERN
>Mature_224_residues
MQRAAYQVAEEILKLVSNSAVRPGERLPGERALAERLGCSRNTVREALAALSARGLVEIRMRSGAYLCRQNHPSPDGGRT
GPGEALDALVTLGPALVERVCRVAGVSEHEHAERITARLGRALVDRSPLDAWRGLTAFYSALAEITGNSLLCAAMGSIAR
SGAAGGFENLPELAPAALQQFFAEHVEMLQAMRRHDVALASRCAAGSLDAFGRMLWQKNGGERN

Specific function: Repressor for the uxuRBA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=158, Percent_Identity=34.8101265822785, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 23971; Mature: 23971

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRAAYQVAEEILKLVSNSAVRPGERLPGERALAERLGCSRNTVREALAALSARGLVEIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
MRSGAYLCRQNHPSPDGGRTGPGEALDALVTLGPALVERVCRVAGVSEHEHAERITARLG
HHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RALVDRSPLDAWRGLTAFYSALAEITGNSLLCAAMGSIARSGAAGGFENLPELAPAALQQ
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FFAEHVEMLQAMRRHDVALASRCAAGSLDAFGRMLWQKNGGERN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRAAYQVAEEILKLVSNSAVRPGERLPGERALAERLGCSRNTVREALAALSARGLVEIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
MRSGAYLCRQNHPSPDGGRTGPGEALDALVTLGPALVERVCRVAGVSEHEHAERITARLG
HHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RALVDRSPLDAWRGLTAFYSALAEITGNSLLCAAMGSIARSGAAGGFENLPELAPAALQQ
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FFAEHVEMLQAMRRHDVALASRCAAGSLDAFGRMLWQKNGGERN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]