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The map label for this gene is arnC [H]

Identifier: 78356639

GI number: 78356639

Start: 1625722

End: 1626444

Strand: Reverse

Name: arnC [H]

Synonym: Dde_1596

Alternate gene names: 78356639

Gene position: 1626444-1625722 (Counterclockwise)

Preceding gene: 78356640

Following gene: 78356638

Centisome position: 43.6

GC content: 52.42

Gene sequence:

>723_bases
ATGTCTGACATTACTTTTTTCTCCGTTGTCGTTCCCGTTTTTAACGAAGAAGAAAACCTCCCTGTCCTGTACGACGAAAT
AAGCCGCGCTGCGGCTGTCACAGGCAAAGAGTGGGAGGTTGTCTTTGTTGATGACGGCAGCAAGGACCGCAGCCTTGATG
TCATAAAGGAGCTTGCGGCAAAAAGCTCCCATGTGCGCTTCGTTGCGCTGCGAAACAATTGCGGACAATCTGCCGCATTC
AGTGCGGGCTTTGAAGCTGCCCGCGGCGATGTTATTGTCACCATGGATGCAGACCTGCAGAATGACCCCGCTGATATTCC
TTCCATGCTTGCGGAATACGCCCGAGGCTTTGACATGGTCATAGGATGGCGTGCCAACCGCAAAGATACCGTTGCCAAAA
AAATCGCTTCGAAAATAGGCAACCGTATACGCAACTGGCTGAGCGAGGAAACCGTGCGCGATACGGGCTGCTCACTCAAA
GTCATGCGCAGCAGCATGGCCAAGCGCATCCCGATGTTTACGGGCATGCACCGCTTTCTGCCCACATTGATGAAGTGCCA
AGGCGCCACTGTTTCCGAAGTCAGGGTCAACCACCGTCCCAGACTGCACGGCACATCCAAATATGGCATATGGGACAGGG
CAAAAACGACGTTTTTTGACCTGCTGGCCATCCGCTGGATGAAAAAGCGCTACATCTGTTACGCCATCAAAGAAAAAAAC
TGA

Upstream 100 bases:

>100_bases
GAGATGTTTCCCTGACCGAGAGGGAGTATCTAGCCCTTGCCGCGACAAGTGTCAACAAGTGATTTACATCCAATGCCGAA
TTGCATATGAAAGCCGAGCT

Downstream 100 bases:

>100_bases
TCCGCCCATGGAAACCCCGGATCTGCGGCACTGGATTCTTTTCTGGAGCGGACTTGCCGCCCAGATTCCGTTTCTGTGGT
TTCTTGTACGTATTTCCTTT

Product: glycosyl transferase, group 2 family protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSDITFFSVVVPVFNEEENLPVLYDEISRAAAVTGKEWEVVFVDDGSKDRSLDVIKELAAKSSHVRFVALRNNCGQSAAF
SAGFEAARGDVIVTMDADLQNDPADIPSMLAEYARGFDMVIGWRANRKDTVAKKIASKIGNRIRNWLSEETVRDTGCSLK
VMRSSMAKRIPMFTGMHRFLPTLMKCQGATVSEVRVNHRPRLHGTSKYGIWDRAKTTFFDLLAIRWMKKRYICYAIKEKN

Sequences:

>Translated_240_residues
MSDITFFSVVVPVFNEEENLPVLYDEISRAAAVTGKEWEVVFVDDGSKDRSLDVIKELAAKSSHVRFVALRNNCGQSAAF
SAGFEAARGDVIVTMDADLQNDPADIPSMLAEYARGFDMVIGWRANRKDTVAKKIASKIGNRIRNWLSEETVRDTGCSLK
VMRSSMAKRIPMFTGMHRFLPTLMKCQGATVSEVRVNHRPRLHGTSKYGIWDRAKTTFFDLLAIRWMKKRYICYAIKEKN
>Mature_239_residues
SDITFFSVVVPVFNEEENLPVLYDEISRAAAVTGKEWEVVFVDDGSKDRSLDVIKELAAKSSHVRFVALRNNCGQSAAFS
AGFEAARGDVIVTMDADLQNDPADIPSMLAEYARGFDMVIGWRANRKDTVAKKIASKIGNRIRNWLSEETVRDTGCSLKV
MRSSMAKRIPMFTGMHRFLPTLMKCQGATVSEVRVNHRPRLHGTSKYGIWDRAKTTFFDLLAIRWMKKRYICYAIKEKN

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=216, Percent_Identity=26.8518518518519, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI7019323, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788588, Length=216, Percent_Identity=37.037037037037, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788692, Length=209, Percent_Identity=31.1004784688995, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787259, Length=91, Percent_Identity=34.0659340659341, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71999402, Length=242, Percent_Identity=28.099173553719, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25146207, Length=233, Percent_Identity=24.8927038626609, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325441, Length=105, Percent_Identity=35.2380952380952, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24585265, Length=217, Percent_Identity=29.9539170506912, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24582769, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 27153; Mature: 27021

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDITFFSVVVPVFNEEENLPVLYDEISRAAAVTGKEWEVVFVDDGSKDRSLDVIKELAA
CCCCEEEHHEEHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHC
KSSHVRFVALRNNCGQSAAFSAGFEAARGDVIVTMDADLQNDPADIPSMLAEYARGFDMV
CCCCEEEEEEECCCCCCHHHHCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEE
IGWRANRKDTVAKKIASKIGNRIRNWLSEETVRDTGCSLKVMRSSMAKRIPMFTGMHRFL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
PTLMKCQGATVSEVRVNHRPRLHGTSKYGIWDRAKTTFFDLLAIRWMKKRYICYAIKEKN
HHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCC
>Mature Secondary Structure 
SDITFFSVVVPVFNEEENLPVLYDEISRAAAVTGKEWEVVFVDDGSKDRSLDVIKELAA
CCCEEEHHEEHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHC
KSSHVRFVALRNNCGQSAAFSAGFEAARGDVIVTMDADLQNDPADIPSMLAEYARGFDMV
CCCCEEEEEEECCCCCCHHHHCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEE
IGWRANRKDTVAKKIASKIGNRIRNWLSEETVRDTGCSLKVMRSSMAKRIPMFTGMHRFL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
PTLMKCQGATVSEVRVNHRPRLHGTSKYGIWDRAKTTFFDLLAIRWMKKRYICYAIKEKN
HHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA