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The map label for this gene is siaT [H]

Identifier: 78356593

GI number: 78356593

Start: 1568503

End: 1569786

Strand: Direct

Name: siaT [H]

Synonym: Dde_1550

Alternate gene names: 78356593

Gene position: 1568503-1569786 (Clockwise)

Preceding gene: 78356592

Following gene: 78356594

Centisome position: 42.05

GC content: 56.78

Gene sequence:

>1284_bases
ATGAGCATTCTTTTGCTGCTTGTCTTTTTTGCCATGCTGGCATCGGGGCTGCCGCTGTTTGTGGCCATGCTGTGTACAGC
ACTGGCCGGGTTTGCCTACATCGGCGAGTCCGGTCAACTGCGGCTGATGGTGCAGCAGTTTTATGGCGGCATGGAACCTT
TTTCCCTGCTGGCCATACCGTACTTTATTCTGGTGGGCGAACTGATGGGCTGCGCCGGACTGACCAGCAGACTGTTGCGT
TTTGCCGAGGCTCTTGTGGGACACCTCAAGGGCGGACTGGGCTATGTGACAGTGGTGGCCAGCATCATTTTTGCCGGTGT
CAACGGCTCTGCCGCGGCGGATGCGTCCGCAGTAGGCTCCATCATGATTCCCGCCATGAAAAAAGGCGGATACCCCGACT
CGTATGCCGCGGGCCTTACTGCCGGCAGTTCGCTTATCGGTCCCATCATTCCGCCGAGCATTTTTATGATTTTGTTCGGC
GCCATGACAAAGACGAATGTGGGCGGGCTGTTTATGGCGGGTGTGGTGCCGGGGTTGCTGCTTGGTGTCGCTTTTATGGT
CATGCACCGCATCAGTGCCGCGCGGCTCAACCTGCCTACGGTCAATACGGCCTTTTCCATGCCTGATCTCTGGAGGGCCA
CCGGCGGAGCCATGGCTGCGCTCATTGCTCCGGGTATCATTATCGGCGGTATCCTGTTCGGGTTCATGACCCCCACCGAG
TCCGGTGCCATAGCCAGTCTGTATGTGGTCATCGTGGGCTTTGTCTGGACACGGCAGCTGACGGTGAAGGGCGTGCTGCT
GGCGTTGTCGAACACGGTCCGGCTTACCAGTGTCATTTTTGTGGTTATCGGGGCGGCGACTATTGTCGGCTGGATTCTGT
CTGCCGAAAAAGTACCGCAGTCCATGGCTCCGGTGATCATGAGTTATGCCTCGAGTCCTGAACAGGTTCTGCTGCTGATA
AGCCTGATTGTGTTTGTGGTGGGCATGTTCATGGAAGAAATTGCGGCTCTGGTGCTGCTTACTCCGGTGTTCGCGCCGCT
GGCTGTGGCGGCGGGAATTGATCCGTATCATTTCGGCATCGTGATGACACTGAACATCACCATTGCGCTTATCACTCCGC
CCATGGGAGCCTGCGTGTACATCGTATCCTCCGTGGGCAATGTGTCGCTGGAAAAAATGTTCAGGCACATCTGGCCGTTT
GTTCTGGTGGCGCTGGCCTGTCAGCTGCTGCTGATTTTTGTTCCCGGGATATCTGTCTGGCTGCCGCATATGCTGGGCTA
TTAA

Upstream 100 bases:

>100_bases
TGGCGCTGATGCTTGCAGAATACGCATTGCAGCAGTTCATCGCACTTGATGCGCTGGCCGCCCGCCCCGTGCGCGGTGCA
TCAGAGGGGGAAGACGCGTC

Downstream 100 bases:

>100_bases
CATTGCTGACCGGCGCGGGCTGATGCCGCGCCGGTCGTTTTTTGCGGAGAACATAATGTATAATCACTACAGCGCCCCCA
TTCCCGCTGTACGTTCCCAC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSILLLLVFFAMLASGLPLFVAMLCTALAGFAYIGESGQLRLMVQQFYGGMEPFSLLAIPYFILVGELMGCAGLTSRLLR
FAEALVGHLKGGLGYVTVVASIIFAGVNGSAAADASAVGSIMIPAMKKGGYPDSYAAGLTAGSSLIGPIIPPSIFMILFG
AMTKTNVGGLFMAGVVPGLLLGVAFMVMHRISAARLNLPTVNTAFSMPDLWRATGGAMAALIAPGIIIGGILFGFMTPTE
SGAIASLYVVIVGFVWTRQLTVKGVLLALSNTVRLTSVIFVVIGAATIVGWILSAEKVPQSMAPVIMSYASSPEQVLLLI
SLIVFVVGMFMEEIAALVLLTPVFAPLAVAAGIDPYHFGIVMTLNITIALITPPMGACVYIVSSVGNVSLEKMFRHIWPF
VLVALACQLLLIFVPGISVWLPHMLGY

Sequences:

>Translated_427_residues
MSILLLLVFFAMLASGLPLFVAMLCTALAGFAYIGESGQLRLMVQQFYGGMEPFSLLAIPYFILVGELMGCAGLTSRLLR
FAEALVGHLKGGLGYVTVVASIIFAGVNGSAAADASAVGSIMIPAMKKGGYPDSYAAGLTAGSSLIGPIIPPSIFMILFG
AMTKTNVGGLFMAGVVPGLLLGVAFMVMHRISAARLNLPTVNTAFSMPDLWRATGGAMAALIAPGIIIGGILFGFMTPTE
SGAIASLYVVIVGFVWTRQLTVKGVLLALSNTVRLTSVIFVVIGAATIVGWILSAEKVPQSMAPVIMSYASSPEQVLLLI
SLIVFVVGMFMEEIAALVLLTPVFAPLAVAAGIDPYHFGIVMTLNITIALITPPMGACVYIVSSVGNVSLEKMFRHIWPF
VLVALACQLLLIFVPGISVWLPHMLGY
>Mature_426_residues
SILLLLVFFAMLASGLPLFVAMLCTALAGFAYIGESGQLRLMVQQFYGGMEPFSLLAIPYFILVGELMGCAGLTSRLLRF
AEALVGHLKGGLGYVTVVASIIFAGVNGSAAADASAVGSIMIPAMKKGGYPDSYAAGLTAGSSLIGPIIPPSIFMILFGA
MTKTNVGGLFMAGVVPGLLLGVAFMVMHRISAARLNLPTVNTAFSMPDLWRATGGAMAALIAPGIIIGGILFGFMTPTES
GAIASLYVVIVGFVWTRQLTVKGVLLALSNTVRLTSVIFVVIGAATIVGWILSAEKVPQSMAPVIMSYASSPEQVLLLIS
LIVFVVGMFMEEIAALVLLTPVFAPLAVAAGIDPYHFGIVMTLNITIALITPPMGACVYIVSSVGNVSLEKMFRHIWPFV
LVALACQLLLIFVPGISVWLPHMLGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=405, Percent_Identity=36.7901234567901, Blast_Score=234, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44745; Mature: 44614

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILLLLVFFAMLASGLPLFVAMLCTALAGFAYIGESGQLRLMVQQFYGGMEPFSLLAIP
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCHHHHHHHH
YFILVGELMGCAGLTSRLLRFAEALVGHLKGGLGYVTVVASIIFAGVNGSAAADASAVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IMIPAMKKGGYPDSYAAGLTAGSSLIGPIIPPSIFMILFGAMTKTNVGGLFMAGVVPGLL
HHHHHHHCCCCCCHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGVAFMVMHRISAARLNLPTVNTAFSMPDLWRATGGAMAALIAPGIIIGGILFGFMTPTE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
SGAIASLYVVIVGFVWTRQLTVKGVLLALSNTVRLTSVIFVVIGAATIVGWILSAEKVPQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SMAPVIMSYASSPEQVLLLISLIVFVVGMFMEEIAALVLLTPVFAPLAVAAGIDPYHFGI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHE
VMTLNITIALITPPMGACVYIVSSVGNVSLEKMFRHIWPFVLVALACQLLLIFVPGISVW
EEEEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LPHMLGY
HHHHHCC
>Mature Secondary Structure 
SILLLLVFFAMLASGLPLFVAMLCTALAGFAYIGESGQLRLMVQQFYGGMEPFSLLAIP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCHHHHHHHH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HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]