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The map label for this gene is rpfC [H]

Identifier: 78356567

GI number: 78356567

Start: 1542259

End: 1543893

Strand: Direct

Name: rpfC [H]

Synonym: Dde_1522

Alternate gene names: 78356567

Gene position: 1542259-1543893 (Clockwise)

Preceding gene: 78356566

Following gene: 78356568

Centisome position: 41.34

GC content: 55.72

Gene sequence:

>1635_bases
ATGAGACACAGGATGGCTGAGTGTGCTCTTCCCCGCGTGCTGGCTATAGATGACGAGTCTTCCGTCCGGCAGAGTCTGGC
GATTTTTTTTGAAGACTGCGGTTACGAGGTGCTGGAGGCGTCTGACGGCTATGAAGGCATTGAAACCGCTCTGCGTGAAC
GGCCCGATGTCATTCTGGTAGATTTGCGCATGCCCGGCATTGACGGCATAGAGGTGCTGCGCAGGCTTTCTTCCGAACTT
CCCGATACTCCCGCCATTGCCGTTTCCGGCGTGGGCGTGCTTGAACAGGCTCTTGAAGCCATGCGCAGCGGCGCTTGGGA
TTTCATTTCCAAGCCTGTCGAAGATTTTGAAGTGCTCAGAAAGGCCGTGGAATCCGCCCGCGAACGGGCGGACCGCAAAC
GCCGCAAGCGGGGCTACCACCAGCATCTTGAACGGGAGGTGGCGGCAAGAACCCGGGAACTGGCCATGGCCAAGGAAGAG
GCGGAACTGGCCAGCAGGGCCAAGTCGCAGTTTCTTGCCAACATGAGCCACGAACTGCGTACACCGCTTAACGGGATAAT
CGGGCTTACCGATCTGCTGCTGTGCGCCCCCGCCGGCGGCGACCACCGTGAATATCTTGAAATGGTAAAGCAGGCGGGTC
AGGAACTGCTGACCATTGTCAATAATCTTCTGGATATGTCCAGCATTGAGGCCTGCCGTCTGGTGCTGCGCGAAACGCCT
TTCTCGCTGCGCGAAAGCGTGGGCGAGGTCAAGCGCATTCTCGAAATTCAGGCCAGATGGAAAAACCTCGATTTTGCAGT
GTTTTTTGATGACGGGATTCCCGATCTGTTTGTGGGTGATGCAGGCAGGCTGAAGCAGATACTGAGTAATCTGCTGGTCA
ACGCCATAAAGTATACCGATAAAGGGGGCGTATCGCTGCGCGTCTCTTCTGCACCGTGCACTGCCGGTGATACAGTCAGG
TTATGCTTTTATGTGCAGGATACCGGAGTGGGGATTGATCCGGAAAAGCGCGAGACCATATTTGAGCCGTTTGTTCTCGG
CGAAAGTTTTATGACCAAAAAGAGTGGCGGAGCAGGGCTGGGGCTGGCTATTTCGCGCGAACTGGCCCGTAAAATGGGGG
GGGATGTGCACGCGTCACGCTGCGCCGAAGGCGGCAGCCTGTTTGAGTGCATCGTCGAGCTGCGCAAATGTGAAGAAGAA
GCGCCTGTGGCAGCCGAAAAAACATGTCCGCTTGCGAGAACGTCCAAGCCGCTGCGTATTCTGCTGGCGGAGGACGATAT
AATAAACCGTAAACTTGCCGTGTTCTTTTTTGAAAAAATGGGTCATGCCGTAAGGGCTGTGGGCACCGGTATAGAAGTGC
TGCAGGCGCTTGCGCAGGAACCTTTTGATCTGATTCTCATGGATATCCAGATGCCGGATATGGACGGTGTGGAGGCTACC
CGCGCCATCCGCAGCGCGCAGGGCGGCAGAATCAGATCTGATATCCCCATCATTGCCATGACGGCCCATGCCATGAAGGG
CGACAAAGAGCGTTTTCTTACTGCCGGTATGGACGGATATGTTTCAAAGCCGGTGGACTTTCCTGCGCTGATGCAGCGCA
TTGAAGCTCTTTCGCAGCAGCAATCAAAGCTGTAG

Upstream 100 bases:

>100_bases
TAGAGGTGATGAATGTCGGTGTAACCCATGAAGATATCTATATAAAGCCTTTGCAGAATATGGATATGCTGGTACGGGGC
ATTGATCGCCTGCTGGCAAA

Downstream 100 bases:

>100_bases
TGCAATTTTTTGAACCTTTCCTCAGGCCGCCATGTCATACGTATTTTGTTTGAATATCTTACATTTGTTTTACCTTCAGG
TGTCTTTTCTGCGCCGGGCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MRHRMAECALPRVLAIDDESSVRQSLAIFFEDCGYEVLEASDGYEGIETALRERPDVILVDLRMPGIDGIEVLRRLSSEL
PDTPAIAVSGVGVLEQALEAMRSGAWDFISKPVEDFEVLRKAVESARERADRKRRKRGYHQHLEREVAARTRELAMAKEE
AELASRAKSQFLANMSHELRTPLNGIIGLTDLLLCAPAGGDHREYLEMVKQAGQELLTIVNNLLDMSSIEACRLVLRETP
FSLRESVGEVKRILEIQARWKNLDFAVFFDDGIPDLFVGDAGRLKQILSNLLVNAIKYTDKGGVSLRVSSAPCTAGDTVR
LCFYVQDTGVGIDPEKRETIFEPFVLGESFMTKKSGGAGLGLAISRELARKMGGDVHASRCAEGGSLFECIVELRKCEEE
APVAAEKTCPLARTSKPLRILLAEDDIINRKLAVFFFEKMGHAVRAVGTGIEVLQALAQEPFDLILMDIQMPDMDGVEAT
RAIRSAQGGRIRSDIPIIAMTAHAMKGDKERFLTAGMDGYVSKPVDFPALMQRIEALSQQQSKL

Sequences:

>Translated_544_residues
MRHRMAECALPRVLAIDDESSVRQSLAIFFEDCGYEVLEASDGYEGIETALRERPDVILVDLRMPGIDGIEVLRRLSSEL
PDTPAIAVSGVGVLEQALEAMRSGAWDFISKPVEDFEVLRKAVESARERADRKRRKRGYHQHLEREVAARTRELAMAKEE
AELASRAKSQFLANMSHELRTPLNGIIGLTDLLLCAPAGGDHREYLEMVKQAGQELLTIVNNLLDMSSIEACRLVLRETP
FSLRESVGEVKRILEIQARWKNLDFAVFFDDGIPDLFVGDAGRLKQILSNLLVNAIKYTDKGGVSLRVSSAPCTAGDTVR
LCFYVQDTGVGIDPEKRETIFEPFVLGESFMTKKSGGAGLGLAISRELARKMGGDVHASRCAEGGSLFECIVELRKCEEE
APVAAEKTCPLARTSKPLRILLAEDDIINRKLAVFFFEKMGHAVRAVGTGIEVLQALAQEPFDLILMDIQMPDMDGVEAT
RAIRSAQGGRIRSDIPIIAMTAHAMKGDKERFLTAGMDGYVSKPVDFPALMQRIEALSQQQSKL
>Mature_544_residues
MRHRMAECALPRVLAIDDESSVRQSLAIFFEDCGYEVLEASDGYEGIETALRERPDVILVDLRMPGIDGIEVLRRLSSEL
PDTPAIAVSGVGVLEQALEAMRSGAWDFISKPVEDFEVLRKAVESARERADRKRRKRGYHQHLEREVAARTRELAMAKEE
AELASRAKSQFLANMSHELRTPLNGIIGLTDLLLCAPAGGDHREYLEMVKQAGQELLTIVNNLLDMSSIEACRLVLRETP
FSLRESVGEVKRILEIQARWKNLDFAVFFDDGIPDLFVGDAGRLKQILSNLLVNAIKYTDKGGVSLRVSSAPCTAGDTVR
LCFYVQDTGVGIDPEKRETIFEPFVLGESFMTKKSGGAGLGLAISRELARKMGGDVHASRCAEGGSLFECIVELRKCEEE
APVAAEKTCPLARTSKPLRILLAEDDIINRKLAVFFFEKMGHAVRAVGTGIEVLQALAQEPFDLILMDIQMPDMDGVEAT
RAIRSAQGGRIRSDIPIIAMTAHAMKGDKERFLTAGMDGYVSKPVDFPALMQRIEALSQQQSKL

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=400, Percent_Identity=34.5, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87081816, Length=423, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=38.0165289256198, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1788713, Length=396, Percent_Identity=30.050505050505, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=36.9402985074627, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=30.3149606299213, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=36.0294117647059, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786600, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=31.5068493150685, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=30.4, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=214, Percent_Identity=29.9065420560748, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=102, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=28.82096069869, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=261, Percent_Identity=25.6704980842912, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=121, Percent_Identity=30.5785123966942, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788905, Length=130, Percent_Identity=30, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=127, Percent_Identity=29.1338582677165, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=124, Percent_Identity=36.2903225806452, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322044, Length=168, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60108; Mature: 60108

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHRMAECALPRVLAIDDESSVRQSLAIFFEDCGYEVLEASDGYEGIETALRERPDVILV
CCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCEEEE
DLRMPGIDGIEVLRRLSSELPDTPAIAVSGVGVLEQALEAMRSGAWDFISKPVEDFEVLR
EECCCCCCHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
KAVESARERADRKRRKRGYHQHLEREVAARTRELAMAKEEAELASRAKSQFLANMSHELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLNGIIGLTDLLLCAPAGGDHREYLEMVKQAGQELLTIVNNLLDMSSIEACRLVLRETP
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSLRESVGEVKRILEIQARWKNLDFAVFFDDGIPDLFVGDAGRLKQILSNLLVNAIKYTD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCC
KGGVSLRVSSAPCTAGDTVRLCFYVQDTGVGIDPEKRETIFEPFVLGESFMTKKSGGAGL
CCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCC
GLAISRELARKMGGDVHASRCAEGGSLFECIVELRKCEEEAPVAAEKTCPLARTSKPLRI
HHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEE
LLAEDDIINRKLAVFFFEKMGHAVRAVGTGIEVLQALAQEPFDLILMDIQMPDMDGVEAT
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
RAIRSAQGGRIRSDIPIIAMTAHAMKGDKERFLTAGMDGYVSKPVDFPALMQRIEALSQQ
HHHHHCCCCCCCCCCCEEEEEHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QSKL
HHCC
>Mature Secondary Structure
MRHRMAECALPRVLAIDDESSVRQSLAIFFEDCGYEVLEASDGYEGIETALRERPDVILV
CCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCEEEE
DLRMPGIDGIEVLRRLSSELPDTPAIAVSGVGVLEQALEAMRSGAWDFISKPVEDFEVLR
EECCCCCCHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
KAVESARERADRKRRKRGYHQHLEREVAARTRELAMAKEEAELASRAKSQFLANMSHELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLNGIIGLTDLLLCAPAGGDHREYLEMVKQAGQELLTIVNNLLDMSSIEACRLVLRETP
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSLRESVGEVKRILEIQARWKNLDFAVFFDDGIPDLFVGDAGRLKQILSNLLVNAIKYTD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCC
KGGVSLRVSSAPCTAGDTVRLCFYVQDTGVGIDPEKRETIFEPFVLGESFMTKKSGGAGL
CCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCC
GLAISRELARKMGGDVHASRCAEGGSLFECIVELRKCEEEAPVAAEKTCPLARTSKPLRI
HHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEE
LLAEDDIINRKLAVFFFEKMGHAVRAVGTGIEVLQALAQEPFDLILMDIQMPDMDGVEAT
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
RAIRSAQGGRIRSDIPIIAMTAHAMKGDKERFLTAGMDGYVSKPVDFPALMQRIEALSQQ
HHHHHCCCCCCCCCCCEEEEEHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QSKL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]