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The map label for this gene is lolC [H]

Identifier: 78356413

GI number: 78356413

Start: 1385066

End: 1386292

Strand: Direct

Name: lolC [H]

Synonym: Dde_1366

Alternate gene names: 78356413

Gene position: 1385066-1386292 (Clockwise)

Preceding gene: 78356412

Following gene: 78356414

Centisome position: 37.13

GC content: 57.13

Gene sequence:

>1227_bases
ATGCGTTTTGAGCTGTTTGTTGCGTTGCGTTATCTGTTTGCCCGCCGCAAGCAGACTTTCATTTCGGTCATATCCGTCAT
TTCGGTGCTGGGTGTGGCTCTGGGCGTGGCATCGCTCATCGTGGTGCTGGGCGTTATGAACGGCTTCACCGTGGATATGC
GTGAAAAGATACTGGGCGTGAACGCCCATGTCATCACGCTGGCTGCGGGCGGCGGTATTTCCGGCTATCCTGAACTGGTG
CGCAAGGCCGAAACCGTTCCGGGAGTAAAGGGCGCGACCCCGTTCATTTATTCCGAGGTCATGCTTTCGACCCGCTACGG
AGTCAAAGGTGTGGTGCTGCGCGGGGTGGACCCCGTTTCGGCGCCGGCGGTGCTGGGCATTGCCGGCCGCATGGTAGACG
GTTCTCTGGCCGACCTTGAACGATCCGGTGCGCCGGGTCTTGTCATCGGTAAAGAACTGGCCAAACGGCTGGGTATCACC
GTGGGCAGCAGGGTCAACCTGCTGTCTCCTTCGGGCGAAAAAACAAGCGCGGGGTTTACCCCGCGCATCCTTTCTTTCAA
GATCGCAGGTATTTTTTCTACCGGCATGTTCGAGTATGACTCGTCGCTGGGGTTCGTCTCGCTTGATGCCGCCCGTGATC
TGCTGGGAATGCCTGCTGGCACTGTTTCTGGTCTTGAAATAGTGGTGGATGACATTTACCGCGCCGATACCGTGGCGCAG
GCGGTTACTCAGGCTCTGGGCGGGTATCCTTTTTACAGCCGCAACTGGATGGAAATGAATGCCAACCTTTTTGCGGCGCT
CAAGCTGGAAAAAGCTGCCATGTCCATCATGCTCACCCTCATAGTGCTGGTGGGGTCTTTTTCCATTGTCACCACACTGG
TGATGCTGGTTATGGAAAAATCGCGCGATATCGCCATCATGATGTCCATGGGCGCTACAAAATCACATATCCGGCGCATT
TTCATGCTGCAGGGTACTATCATAGGCGTTGTGGGCACCACTCTGGGATTCGGGCTGGGGCTGCTTGTGTGCTGGCTGCT
CAAGCGTTATCAGTTCATCAAACTGCCGCCCGGCGTCTATTCGCTTGACCATCTGCCCGTGCTGCTGCAGTGGCAGGATC
TGGCAGCCATTGCCGTCGGTGCCATGGTGCTGTGCTTTCTTGCCACCATCTATCCTGCGCGGCAGGCGTCTTCACTGGAG
CCTGCCGAGGCGCTGCGGTACGAATGA

Upstream 100 bases:

>100_bases
TCCCGCTGCTTAAGCTGGAGAGCTGATCTGAAAACGGCAACAGCAGTCGCCATACCGGGCCGCAGTCAGGCCCGCCAACC
GGAAAGGACAAGCCAGCAGC

Downstream 100 bases:

>100_bases
TGGAAAAAAATACCATGCTGTTCAGCCTGAAAGATGTGGGTAAAGAATATCAGGGTCCTGCAGAAAAAATTATTATTTTC
AGCCGGTTGAATCTTGATAT

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRFELFVALRYLFARRKQTFISVISVISVLGVALGVASLIVVLGVMNGFTVDMREKILGVNAHVITLAAGGGISGYPELV
RKAETVPGVKGATPFIYSEVMLSTRYGVKGVVLRGVDPVSAPAVLGIAGRMVDGSLADLERSGAPGLVIGKELAKRLGIT
VGSRVNLLSPSGEKTSAGFTPRILSFKIAGIFSTGMFEYDSSLGFVSLDAARDLLGMPAGTVSGLEIVVDDIYRADTVAQ
AVTQALGGYPFYSRNWMEMNANLFAALKLEKAAMSIMLTLIVLVGSFSIVTTLVMLVMEKSRDIAIMMSMGATKSHIRRI
FMLQGTIIGVVGTTLGFGLGLLVCWLLKRYQFIKLPPGVYSLDHLPVLLQWQDLAAIAVGAMVLCFLATIYPARQASSLE
PAEALRYE

Sequences:

>Translated_408_residues
MRFELFVALRYLFARRKQTFISVISVISVLGVALGVASLIVVLGVMNGFTVDMREKILGVNAHVITLAAGGGISGYPELV
RKAETVPGVKGATPFIYSEVMLSTRYGVKGVVLRGVDPVSAPAVLGIAGRMVDGSLADLERSGAPGLVIGKELAKRLGIT
VGSRVNLLSPSGEKTSAGFTPRILSFKIAGIFSTGMFEYDSSLGFVSLDAARDLLGMPAGTVSGLEIVVDDIYRADTVAQ
AVTQALGGYPFYSRNWMEMNANLFAALKLEKAAMSIMLTLIVLVGSFSIVTTLVMLVMEKSRDIAIMMSMGATKSHIRRI
FMLQGTIIGVVGTTLGFGLGLLVCWLLKRYQFIKLPPGVYSLDHLPVLLQWQDLAAIAVGAMVLCFLATIYPARQASSLE
PAEALRYE
>Mature_408_residues
MRFELFVALRYLFARRKQTFISVISVISVLGVALGVASLIVVLGVMNGFTVDMREKILGVNAHVITLAAGGGISGYPELV
RKAETVPGVKGATPFIYSEVMLSTRYGVKGVVLRGVDPVSAPAVLGIAGRMVDGSLADLERSGAPGLVIGKELAKRLGIT
VGSRVNLLSPSGEKTSAGFTPRILSFKIAGIFSTGMFEYDSSLGFVSLDAARDLLGMPAGTVSGLEIVVDDIYRADTVAQ
AVTQALGGYPFYSRNWMEMNANLFAALKLEKAAMSIMLTLIVLVGSFSIVTTLVMLVMEKSRDIAIMMSMGATKSHIRRI
FMLQGTIIGVVGTTLGFGLGLLVCWLLKRYQFIKLPPGVYSLDHLPVLLQWQDLAAIAVGAMVLCFLATIYPARQASSLE
PAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=409, Percent_Identity=30.8068459657702, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787362, Length=415, Percent_Identity=30.1204819277108, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43640; Mature: 43640

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFELFVALRYLFARRKQTFISVISVISVLGVALGVASLIVVLGVMNGFTVDMREKILGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCC
NAHVITLAAGGGISGYPELVRKAETVPGVKGATPFIYSEVMLSTRYGVKGVVLRGVDPVS
CEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
APAVLGIAGRMVDGSLADLERSGAPGLVIGKELAKRLGITVGSRVNLLSPSGEKTSAGFT
CCHHHHHHHHHCCCHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
PRILSFKIAGIFSTGMFEYDSSLGFVSLDAARDLLGMPAGTVSGLEIVVDDIYRADTVAQ
CHHHHEEEEHHHHCCCEEECCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVTQALGGYPFYSRNWMEMNANLFAALKLEKAAMSIMLTLIVLVGSFSIVTTLVMLVMEK
HHHHHHCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
SRDIAIMMSMGATKSHIRRIFMLQGTIIGVVGTTLGFGLGLLVCWLLKRYQFIKLPPGVY
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCC
SLDHLPVLLQWQDLAAIAVGAMVLCFLATIYPARQASSLEPAEALRYE
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MRFELFVALRYLFARRKQTFISVISVISVLGVALGVASLIVVLGVMNGFTVDMREKILGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCC
NAHVITLAAGGGISGYPELVRKAETVPGVKGATPFIYSEVMLSTRYGVKGVVLRGVDPVS
CEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
APAVLGIAGRMVDGSLADLERSGAPGLVIGKELAKRLGITVGSRVNLLSPSGEKTSAGFT
CCHHHHHHHHHCCCHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
PRILSFKIAGIFSTGMFEYDSSLGFVSLDAARDLLGMPAGTVSGLEIVVDDIYRADTVAQ
CHHHHEEEEHHHHCCCEEECCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVTQALGGYPFYSRNWMEMNANLFAALKLEKAAMSIMLTLIVLVGSFSIVTTLVMLVMEK
HHHHHHCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
SRDIAIMMSMGATKSHIRRIFMLQGTIIGVVGTTLGFGLGLLVCWLLKRYQFIKLPPGVY
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCC
SLDHLPVLLQWQDLAAIAVGAMVLCFLATIYPARQASSLEPAEALRYE
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]