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The map label for this gene is 78356362

Identifier: 78356362

GI number: 78356362

Start: 1334249

End: 1335721

Strand: Reverse

Name: 78356362

Synonym: Dde_1315

Alternate gene names: NA

Gene position: 1335721-1334249 (Counterclockwise)

Preceding gene: 78356364

Following gene: 78356361

Centisome position: 35.81

GC content: 57.57

Gene sequence:

>1473_bases
ATGCGGGTTTTTCCATCCGGTACCATGACAGAACAACAGACACCTGCTGCAGACGACAGCCCCCGCGCCGGTAACGGCCA
GACGGCTTTTGCCCCTTTTGCCCGCAAAATGCGGCTGCATGGCCTATCCGAAGGGCTGATACGCCTTTTTAACAGTTACT
ACGACGAAATCGTGGCCCGCCACACCGGCTATCTGCACGAAGCGGAACTGCTGCCTGTCTCCGCTGCCGACCTGCCTCAT
GTCGATTCGCTGGAGTCCTTCCGCGAAGCAGGCAGACAGGCGGCGCGTCAGGCTGTGGTTATCAAGCTGAACGGCGGACT
GGGTACCAGCATGGGCATGACCCATGCAAAATCGCTTATACCCGTTTTCGGCGAGATGCGCTTTCTGGACATTATTATGC
AGCAGGCCCTGCTGCAGCAAAAAGAGTGCGGCGGCCCGCTGCCGCTTGCTCTCATGAACAGCTTCAGCACGCACGAAGAA
ACTCTGCAGGCACTTGCCGACATACGCGAAGAAGACTGCCGCCAGTGCACACCGGTGTGCTTTGTGCAGCACAAATTTCC
CAAGGTTTCACGCCGTACGCTGCAGCCTGTGTCGTACCCGCAAAGTCCGGACATGGAATGGAACCCGCCCGGACACGGCG
ACCTGTATGCTTCGCTGGTCACTTCAGGCGTGCTGGACGATCTGCTCTCCCACGGGCGCCGCTATGCCTTTGTCTCCAAC
TCCGACAATCTGGGTGCCGTGCTGGATATGCGCATTCTCGGATACATGGCCGGCAACGAGTTGCCCTTTATCATGGAGGT
GGCTCCGCGCACAGCTTCTGACAAAAAGGGCGGTCATCTGGCGCAACACCGCGACGGCGGTCTGATACTGCGCGAACTGG
CGCAGTGCCCCCCCGATGAAACCGACGCCTTTCAGGATATCCGCCGTTACGGACTTTTCAATACCAACAACCTGTGGGTC
GACCTGCACGCGCTTAAAAAACGCATTGAAAAAGAGGGACTCCTGCGTCTGCCGGTCATCCTCAATCCCAAAACGGTGAA
CCCGCGGGACAAAAGCTCGGAACCGGTCTGGCAGGTGGAAACAGCCATGGGAGCGGGTATTTCCATGTTTACCGGTGCGC
AGGCCGTAGTGGTCAACCGTGACAGATTCATCCCCGTCAAAAAATGTTCCGACCTGCTGGCCGTCATGTCCGACTGCTTC
GCGCTGAATCAGGGCACGGTGAGCTTCAGTCCGGAATGCCGCTACCCCACCCCGCAGGTCACTCTGGACGACAGGTACTA
CGACCATTACGACAAACTGCTGCAGCGCATTCCATATGGTCCGCCTTCGCTGAAAGAGTGCAGCAGTCTGACCATAAAAG
GCGATGTGACCTTTGGCAGAAACGTGGTTATCCGCGGCGACACAACCATCACAACCGGCGGAACCGCACATATTCCGGAC
AATACGGAACTTGAAGGCGAAGTAATACTGTAG

Upstream 100 bases:

>100_bases
AAATTTATACTGGCAATATACCACAGTTATCGTAATATACAGGTTCGTTTTTCCGGTTTTCCGCATCACAACCGCAACCC
ACACGGAGCCTGTGACACCC

Downstream 100 bases:

>100_bases
TTTTTCACGCGTTCGCATCCATACAAAACACAGAGTTCAGGGCAACGGTCTGCAGCCGTTGCCTTTTTCAGTGTTCCGCA
AAGCTCTAGAAAATGTCTTG

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: diphosphate; UDP-glucose

Alternate protein names: UDP-Glucose Pyrophosphorylase; UTP-Glucose-1-Phosphate Uridyltransferase; Nucleotide Glucose-1-Phosphate Uridylyl Transferase; Glucose-1-Phosphate Uridylyltransferase; Utp-Glucose-1-Phosphate Uridylyltransferase; Molybdenum Cofactor Synthesis Domain Protein

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MRVFPSGTMTEQQTPAADDSPRAGNGQTAFAPFARKMRLHGLSEGLIRLFNSYYDEIVARHTGYLHEAELLPVSAADLPH
VDSLESFREAGRQAARQAVVIKLNGGLGTSMGMTHAKSLIPVFGEMRFLDIIMQQALLQQKECGGPLPLALMNSFSTHEE
TLQALADIREEDCRQCTPVCFVQHKFPKVSRRTLQPVSYPQSPDMEWNPPGHGDLYASLVTSGVLDDLLSHGRRYAFVSN
SDNLGAVLDMRILGYMAGNELPFIMEVAPRTASDKKGGHLAQHRDGGLILRELAQCPPDETDAFQDIRRYGLFNTNNLWV
DLHALKKRIEKEGLLRLPVILNPKTVNPRDKSSEPVWQVETAMGAGISMFTGAQAVVVNRDRFIPVKKCSDLLAVMSDCF
ALNQGTVSFSPECRYPTPQVTLDDRYYDHYDKLLQRIPYGPPSLKECSSLTIKGDVTFGRNVVIRGDTTITTGGTAHIPD
NTELEGEVIL

Sequences:

>Translated_490_residues
MRVFPSGTMTEQQTPAADDSPRAGNGQTAFAPFARKMRLHGLSEGLIRLFNSYYDEIVARHTGYLHEAELLPVSAADLPH
VDSLESFREAGRQAARQAVVIKLNGGLGTSMGMTHAKSLIPVFGEMRFLDIIMQQALLQQKECGGPLPLALMNSFSTHEE
TLQALADIREEDCRQCTPVCFVQHKFPKVSRRTLQPVSYPQSPDMEWNPPGHGDLYASLVTSGVLDDLLSHGRRYAFVSN
SDNLGAVLDMRILGYMAGNELPFIMEVAPRTASDKKGGHLAQHRDGGLILRELAQCPPDETDAFQDIRRYGLFNTNNLWV
DLHALKKRIEKEGLLRLPVILNPKTVNPRDKSSEPVWQVETAMGAGISMFTGAQAVVVNRDRFIPVKKCSDLLAVMSDCF
ALNQGTVSFSPECRYPTPQVTLDDRYYDHYDKLLQRIPYGPPSLKECSSLTIKGDVTFGRNVVIRGDTTITTGGTAHIPD
NTELEGEVIL
>Mature_490_residues
MRVFPSGTMTEQQTPAADDSPRAGNGQTAFAPFARKMRLHGLSEGLIRLFNSYYDEIVARHTGYLHEAELLPVSAADLPH
VDSLESFREAGRQAARQAVVIKLNGGLGTSMGMTHAKSLIPVFGEMRFLDIIMQQALLQQKECGGPLPLALMNSFSTHEE
TLQALADIREEDCRQCTPVCFVQHKFPKVSRRTLQPVSYPQSPDMEWNPPGHGDLYASLVTSGVLDDLLSHGRRYAFVSN
SDNLGAVLDMRILGYMAGNELPFIMEVAPRTASDKKGGHLAQHRDGGLILRELAQCPPDETDAFQDIRRYGLFNTNNLWV
DLHALKKRIEKEGLLRLPVILNPKTVNPRDKSSEPVWQVETAMGAGISMFTGAQAVVVNRDRFIPVKKCSDLLAVMSDCF
ALNQGTVSFSPECRYPTPQVTLDDRYYDHYDKLLQRIPYGPPSLKECSSLTIKGDVTFGRNVVIRGDTTITTGGTAHIPD
NTELEGEVIL

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI48255966, Length=404, Percent_Identity=40.5940594059406, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI48255968, Length=404, Percent_Identity=40.5940594059406, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17554112, Length=404, Percent_Identity=41.0891089108911, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71988370, Length=404, Percent_Identity=41.0891089108911, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17554114, Length=404, Percent_Identity=41.0891089108911, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI71988365, Length=404, Percent_Identity=41.0891089108911, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17554108, Length=404, Percent_Identity=41.0891089108911, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI17554110, Length=393, Percent_Identity=40.2035623409669, Blast_Score=261, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI25151022, Length=413, Percent_Identity=36.5617433414044, Blast_Score=223, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322815, Length=396, Percent_Identity=41.6666666666667, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321775, Length=449, Percent_Identity=27.3942093541203, Blast_Score=156, Evalue=9e-39,
Organism=Drosophila melanogaster, GI281365929, Length=412, Percent_Identity=40.5339805825243, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI62484452, Length=409, Percent_Identity=40.5867970660147, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI281365931, Length=412, Percent_Identity=40.5339805825243, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI62484278, Length=409, Percent_Identity=40.5867970660147, Blast_Score=282, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.9

Molecular weight: Translated: 54241; Mature: 54241

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFPSGTMTEQQTPAADDSPRAGNGQTAFAPFARKMRLHGLSEGLIRLFNSYYDEIVAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
HTGYLHEAELLPVSAADLPHVDSLESFREAGRQAARQAVVIKLNGGLGTSMGMTHAKSLI
HCCCCEECCCCEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHH
PVFGEMRFLDIIMQQALLQQKECGGPLPLALMNSFSTHEETLQALADIREEDCRQCTPVC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEE
FVQHKFPKVSRRTLQPVSYPQSPDMEWNPPGHGDLYASLVTSGVLDDLLSHGRRYAFVSN
EEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
SDNLGAVLDMRILGYMAGNELPFIMEVAPRTASDKKGGHLAQHRDGGLILRELAQCPPDE
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
TDAFQDIRRYGLFNTNNLWVDLHALKKRIEKEGLLRLPVILNPKTVNPRDKSSEPVWQVE
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCEECCEEECCCCCCCCCCCCCCCEEEH
TAMGAGISMFTGAQAVVVNRDRFIPVKKCSDLLAVMSDCFALNQGTVSFSPECRYPTPQV
HHHCCCEEHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCE
TLDDRYYDHYDKLLQRIPYGPPSLKECSSLTIKGDVTFGRNVVIRGDTTITTGGTAHIPD
EECCHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEECCEEEEECCCEEECCCEEECCC
NTELEGEVIL
CCCCCCCEEC
>Mature Secondary Structure
MRVFPSGTMTEQQTPAADDSPRAGNGQTAFAPFARKMRLHGLSEGLIRLFNSYYDEIVAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
HTGYLHEAELLPVSAADLPHVDSLESFREAGRQAARQAVVIKLNGGLGTSMGMTHAKSLI
HCCCCEECCCCEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHH
PVFGEMRFLDIIMQQALLQQKECGGPLPLALMNSFSTHEETLQALADIREEDCRQCTPVC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEE
FVQHKFPKVSRRTLQPVSYPQSPDMEWNPPGHGDLYASLVTSGVLDDLLSHGRRYAFVSN
EEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
SDNLGAVLDMRILGYMAGNELPFIMEVAPRTASDKKGGHLAQHRDGGLILRELAQCPPDE
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
TDAFQDIRRYGLFNTNNLWVDLHALKKRIEKEGLLRLPVILNPKTVNPRDKSSEPVWQVE
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCEECCEEECCCCCCCCCCCCCCCEEEH
TAMGAGISMFTGAQAVVVNRDRFIPVKKCSDLLAVMSDCFALNQGTVSFSPECRYPTPQV
HHHCCCEEHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCE
TLDDRYYDHYDKLLQRIPYGPPSLKECSSLTIKGDVTFGRNVVIRGDTTITTGGTAHIPD
EECCHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEECCEEEEECCCEEECCCEEECCC
NTELEGEVIL
CCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; alpha-D-glucose 1-phosphate

Specific reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA