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The map label for this gene is fadR [H]

Identifier: 78356330

GI number: 78356330

Start: 1301850

End: 1302434

Strand: Reverse

Name: fadR [H]

Synonym: Dde_1283

Alternate gene names: 78356330

Gene position: 1302434-1301850 (Counterclockwise)

Preceding gene: 78356331

Following gene: 78356327

Centisome position: 34.92

GC content: 50.43

Gene sequence:

>585_bases
ATGAAACGCGACATTATTCTGGACACCGCCGCGCGCCTTTTTGCGGAACGCGGCTTCAGCAATACCCCCACCAGCCTGCT
GGCACGCGAAGCAGGTGTGGCCGAAGGGACGATCTTCCGTCATTTCAAGACTAAAGATGACATTTTCCTTACGCTGGTAA
CCAACGTGAAAAACCAGCTCATCAGCGACATCGAAAAGTATCTTGAAGTGCGCACTCCTGAAAGCAGCATGGAAAAGGTC
GTTTCCATCATCAAATCGTTCTATGTTTTCGTTAAAAAAAACAACATGGAATTCTGCCTTATTTTCCGTGATGCTCCCAC
ACGCTACGGCCACAGAAACGACAACGTGTTCCTGCAGATTCAGCAGATATACAGCTATCTTACCGAGTATCTGACACAGG
CCCTTGAAGAGGGTAAACAGGACGGTTCCATACGTTCCGCCCTGAACACCAAGGATACCGCAGGCATGGTGGTCAGCCTT
GTGGTAGGCCTTGTCAGAGCCATGCACTTCGGTTTTGTCGAGCCTTCCGACGATGTGCTGCGCAGCGTCATCGACAATAT
CCGCCATATGCTGACCTGCGAATAA

Upstream 100 bases:

>100_bases
GGCTTCGTGCGTTGACACTTTTGAATGGCAGGAGTATCACCACACCTCTGAGTGAGTGAACACACCGTTTATTATCGCAA
CATACCATTGTAGGGATATC

Downstream 100 bases:

>100_bases
CGCCTGTCAGAAATGTTTTTGCAAAGAGCCGTGCCCGCACGGCTCTTTTTTTTCGGGGTCTTTCCCCGCGGAACCGTCCT
GCAAAAGGCTGAGTGCCCTT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKRDIILDTAARLFAERGFSNTPTSLLAREAGVAEGTIFRHFKTKDDIFLTLVTNVKNQLISDIEKYLEVRTPESSMEKV
VSIIKSFYVFVKKNNMEFCLIFRDAPTRYGHRNDNVFLQIQQIYSYLTEYLTQALEEGKQDGSIRSALNTKDTAGMVVSL
VVGLVRAMHFGFVEPSDDVLRSVIDNIRHMLTCE

Sequences:

>Translated_194_residues
MKRDIILDTAARLFAERGFSNTPTSLLAREAGVAEGTIFRHFKTKDDIFLTLVTNVKNQLISDIEKYLEVRTPESSMEKV
VSIIKSFYVFVKKNNMEFCLIFRDAPTRYGHRNDNVFLQIQQIYSYLTEYLTQALEEGKQDGSIRSALNTKDTAGMVVSL
VVGLVRAMHFGFVEPSDDVLRSVIDNIRHMLTCE
>Mature_194_residues
MKRDIILDTAARLFAERGFSNTPTSLLAREAGVAEGTIFRHFKTKDDIFLTLVTNVKNQLISDIEKYLEVRTPESSMEKV
VSIIKSFYVFVKKNNMEFCLIFRDAPTRYGHRNDNVFLQIQQIYSYLTEYLTQALEEGKQDGSIRSALNTKDTAGMVVSL
VVGLVRAMHFGFVEPSDDVLRSVIDNIRHMLTCE

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22139; Mature: 22139

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDIILDTAARLFAERGFSNTPTSLLAREAGVAEGTIFRHFKTKDDIFLTLVTNVKNQL
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
ISDIEKYLEVRTPESSMEKVVSIIKSFYVFVKKNNMEFCLIFRDAPTRYGHRNDNVFLQI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEH
QQIYSYLTEYLTQALEEGKQDGSIRSALNTKDTAGMVVSLVVGLVRAMHFGFVEPSDDVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RSVIDNIRHMLTCE
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKRDIILDTAARLFAERGFSNTPTSLLAREAGVAEGTIFRHFKTKDDIFLTLVTNVKNQL
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
ISDIEKYLEVRTPESSMEKVVSIIKSFYVFVKKNNMEFCLIFRDAPTRYGHRNDNVFLQI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEH
QQIYSYLTEYLTQALEEGKQDGSIRSALNTKDTAGMVVSLVVGLVRAMHFGFVEPSDDVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RSVIDNIRHMLTCE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]