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The map label for this gene is sglT [H]

Identifier: 78356315

GI number: 78356315

Start: 1283369

End: 1284793

Strand: Direct

Name: sglT [H]

Synonym: Dde_1268

Alternate gene names: 78356315

Gene position: 1283369-1284793 (Clockwise)

Preceding gene: 78356314

Following gene: 78356316

Centisome position: 34.4

GC content: 58.32

Gene sequence:

>1425_bases
ATGACGAGCACATTCTATGTTATTCTGGCCTATATGGCGTGCATGATCGGAATCGGCCTGTGGGTCGCCAAACGCAAAAT
CCGTCAATCTGAAGATTTTCTTCTGGCAGGCCGGCAGCTTGGTCCGGCTATGATGGCAGGGACTCTCGCCGCCGCCGAAA
TCGGCGGCGGCAGTACCCTGGGCGTTGCGGCCAAGGCCTATGGCGAATGGGGTTTTTCCGCAGGATGGTACGTTGTCAGC
GCCGGTATCGGCATCTTTCTGGTGTCGTTCGTCGCCCCGTATCTGCGCCGCTCCATGGCCACCACGGTTCCTGAAATTCT
GGCACGGCGTTACGGCCGCACATCGCATATCATAACCACTTTTCTTTCCATCAGCGCCCTTTTCTTTGCCACGGCTGCGC
AGGTCATTGCCACCTCGTCGGTCATCCATGTGGTAACCGGCGCCGACCTGCCCATGGTCATCATCCTTTCCGGCTGCGTG
GTCACGGCCTACACGCTCATGGGCGGGCTCATGTCGGTGGCCTTTACCGATATCGTGCATATATTCTTCATCACGGTAGG
TATGGCTGTGGCCATGCCCATCATTCTGCACAACTCCGGCGGGTGGGACCATCTTGTGGCCACGCTGCCTCCTTCGCAGA
TGAGCCTGACCAACGTGGGCTGGAAGACTATATTCGGACTTATCCTTATGTACTTCATGACCTTTTCCACAGGTCAGGAA
GCGGTTCAGCGGTATTTTGCCGCACGTAACGCCAAAGTGGCCAAAATGGGCTCCTTCATGTGCTCCTGCCTGATGGCCCT
GTACGGCTTCATTCCGGCAGTCATAGGTCTGGTGGCACTGGCCCACTTCCCCGGTATCGAACCCAACAGTGCGCTGCCCA
CGGCCGCGCAGCATTTCGCCCCGACCATCATCGCAGGCGTGGTTCTGGCATCGGTGGTGGCGGCAACCATGTCCAGCGCC
TCCGGCAACATGCTGGCCGTGTCCACACTGTTCACCAAAGACGTCTTTCAGAAGTATATCCGCCCCGATGCCACAGACAA
GCAGCTCATGACATGGAGCAAGGGCGCCATCCTGTTCGTGGGCATGTGCGCCGTGGGCATCGCGCTGGGTAACTACTCCA
TCATATCGCTGCTCATTCTGGCATTCACCATGCGTGCCGCCGGTCCTTTCGCAGCGTTCGTCTTCGGGCTGATTTATGAA
AAAGCCACCGTAAACGCCGGACTGTACTCCATCATTCTGGGGTCCGTGGCTGCCATCGGATGGCAGCAGGCCGGTGAACC
CTACGGCATCATGGCCATCGTGTTCGGCGCGCTGGTCAGTACCGTGAGCTTCTTTGCGATTTCCAAGATTGAAATCGCCA
TGGGTGTTGCGCCTGCCCCGCTGGCCATCACCGAAGAACACCGCAAGGCGAGCGGCGAAGAGTAG

Upstream 100 bases:

>100_bases
ATGATGAGTACATCGAGCTTGATCAACTCTACAAGGCTGTTGCCGGCTACATGGCCATCAGCCGAGCCCTGCTGCAGGCC
TAGAAGAGGAGTCACCTGCC

Downstream 100 bases:

>100_bases
CAAGGTTATTTGACGGGACGGGCGCGGGTGAAGGCGCGCCCGTCCTGCAGCGTCTCACTGCGCGGGCCGGACGCTGCTTT
TCCGCTGCACCCGGAAAAAA

Product: putative sodium:solute symport protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTSTFYVILAYMACMIGIGLWVAKRKIRQSEDFLLAGRQLGPAMMAGTLAAAEIGGGSTLGVAAKAYGEWGFSAGWYVVS
AGIGIFLVSFVAPYLRRSMATTVPEILARRYGRTSHIITTFLSISALFFATAAQVIATSSVIHVVTGADLPMVIILSGCV
VTAYTLMGGLMSVAFTDIVHIFFITVGMAVAMPIILHNSGGWDHLVATLPPSQMSLTNVGWKTIFGLILMYFMTFSTGQE
AVQRYFAARNAKVAKMGSFMCSCLMALYGFIPAVIGLVALAHFPGIEPNSALPTAAQHFAPTIIAGVVLASVVAATMSSA
SGNMLAVSTLFTKDVFQKYIRPDATDKQLMTWSKGAILFVGMCAVGIALGNYSIISLLILAFTMRAAGPFAAFVFGLIYE
KATVNAGLYSIILGSVAAIGWQQAGEPYGIMAIVFGALVSTVSFFAISKIEIAMGVAPAPLAITEEHRKASGEE

Sequences:

>Translated_474_residues
MTSTFYVILAYMACMIGIGLWVAKRKIRQSEDFLLAGRQLGPAMMAGTLAAAEIGGGSTLGVAAKAYGEWGFSAGWYVVS
AGIGIFLVSFVAPYLRRSMATTVPEILARRYGRTSHIITTFLSISALFFATAAQVIATSSVIHVVTGADLPMVIILSGCV
VTAYTLMGGLMSVAFTDIVHIFFITVGMAVAMPIILHNSGGWDHLVATLPPSQMSLTNVGWKTIFGLILMYFMTFSTGQE
AVQRYFAARNAKVAKMGSFMCSCLMALYGFIPAVIGLVALAHFPGIEPNSALPTAAQHFAPTIIAGVVLASVVAATMSSA
SGNMLAVSTLFTKDVFQKYIRPDATDKQLMTWSKGAILFVGMCAVGIALGNYSIISLLILAFTMRAAGPFAAFVFGLIYE
KATVNAGLYSIILGSVAAIGWQQAGEPYGIMAIVFGALVSTVSFFAISKIEIAMGVAPAPLAITEEHRKASGEE
>Mature_473_residues
TSTFYVILAYMACMIGIGLWVAKRKIRQSEDFLLAGRQLGPAMMAGTLAAAEIGGGSTLGVAAKAYGEWGFSAGWYVVSA
GIGIFLVSFVAPYLRRSMATTVPEILARRYGRTSHIITTFLSISALFFATAAQVIATSSVIHVVTGADLPMVIILSGCVV
TAYTLMGGLMSVAFTDIVHIFFITVGMAVAMPIILHNSGGWDHLVATLPPSQMSLTNVGWKTIFGLILMYFMTFSTGQEA
VQRYFAARNAKVAKMGSFMCSCLMALYGFIPAVIGLVALAHFPGIEPNSALPTAAQHFAPTIIAGVVLASVVAATMSSAS
GNMLAVSTLFTKDVFQKYIRPDATDKQLMTWSKGAILFVGMCAVGIALGNYSIISLLILAFTMRAAGPFAAFVFGLIYEK
ATVNAGLYSIILGSVAAIGWQQAGEPYGIMAIVFGALVSTVSFFAISKIEIAMGVAPAPLAITEEHRKASGEE

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI11141885, Length=403, Percent_Identity=26.0545905707196, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI109659836, Length=470, Percent_Identity=24.468085106383, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4507035, Length=377, Percent_Identity=25.4641909814324, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310128183, Length=400, Percent_Identity=27.25, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI14140236, Length=397, Percent_Identity=23.9294710327456, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI109659839, Length=486, Percent_Identity=23.6625514403292, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4507031, Length=395, Percent_Identity=23.7974683544304, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI17941285, Length=390, Percent_Identity=25.1282051282051, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4507033, Length=399, Percent_Identity=24.812030075188, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI157671931, Length=387, Percent_Identity=25.0645994832041, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI206597483, Length=457, Percent_Identity=23.6323851203501, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI167466278, Length=396, Percent_Identity=22.979797979798, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI256985183, Length=377, Percent_Identity=22.5464190981432, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790113, Length=371, Percent_Identity=25.8760107816712, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787251, Length=466, Percent_Identity=24.4635193133047, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082237, Length=435, Percent_Identity=23.9080459770115, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790503, Length=444, Percent_Identity=20.7207207207207, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17539284, Length=424, Percent_Identity=26.8867924528302, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115533094, Length=445, Percent_Identity=23.3707865168539, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648033, Length=399, Percent_Identity=26.5664160401003, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356865, Length=399, Percent_Identity=26.5664160401003, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24651739, Length=452, Percent_Identity=20.1327433628319, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650192, Length=385, Percent_Identity=21.8181818181818, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573698, Length=362, Percent_Identity=22.0994475138122, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221459584, Length=377, Percent_Identity=22.0159151193634, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50065; Mature: 49934

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTFYVILAYMACMIGIGLWVAKRKIRQSEDFLLAGRQLGPAMMAGTLAAAEIGGGSTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCH
GVAAKAYGEWGFSAGWYVVSAGIGIFLVSFVAPYLRRSMATTVPEILARRYGRTSHIITT
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLSISALFFATAAQVIATSSVIHVVTGADLPMVIILSGCVVTAYTLMGGLMSVAFTDIVH
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFITVGMAVAMPIILHNSGGWDHLVATLPPSQMSLTNVGWKTIFGLILMYFMTFSTGQE
HHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHH
AVQRYFAARNAKVAKMGSFMCSCLMALYGFIPAVIGLVALAHFPGIEPNSALPTAAQHFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
PTIIAGVVLASVVAATMSSASGNMLAVSTLFTKDVFQKYIRPDATDKQLMTWSKGAILFV
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHH
GMCAVGIALGNYSIISLLILAFTMRAAGPFAAFVFGLIYEKATVNAGLYSIILGSVAAIG
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
WQQAGEPYGIMAIVFGALVSTVSFFAISKIEIAMGVAPAPLAITEEHRKASGEE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCC
>Mature Secondary Structure 
TSTFYVILAYMACMIGIGLWVAKRKIRQSEDFLLAGRQLGPAMMAGTLAAAEIGGGSTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCH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HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]