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The map label for this gene is lldR [H]

Identifier: 78356291

GI number: 78356291

Start: 1258907

End: 1259602

Strand: Direct

Name: lldR [H]

Synonym: Dde_1244

Alternate gene names: 78356291

Gene position: 1258907-1259602 (Clockwise)

Preceding gene: 78356283

Following gene: 78356292

Centisome position: 33.75

GC content: 58.33

Gene sequence:

>696_bases
ATGGTGGCTGAAAGTGCGCCGCGCACATCTGTTGCCGCGGAAGTGGCAGAAAAGATACGGCGGATGATTGATGAAGGGCA
GATGCTGCCGGGAGAAAGACTGCCTGCGGAAAGGAAGCTGGCAGGGCTGTTCAATGTCTCGCGTGCGTCGGTACGCGAGG
GGATCAAGCTGCTTGCAGAATCCGGAAGGCTGCTGAGCAGGCAGGGGTCGGGCACATATGTGCGTGAACGTTGTGCAGAA
AACAGTGGCAGGACTCTGGTGCAGACGGTGTTGAACGGCGGGTATTCCCTGCAGGATGTCATTGCCGTGCGTCTGTTGCT
GGAACCGGAGATAGCAGCTCTGGCAGCCCGTAATGGCGGTGCCGCTGTAGCAGCCCGGCTGGAGGCTGTTCTTGCCGAAC
AGGAGATTGCAATCGGCAGCAAGGACTACAGTGGATCCGCTGACGTCCTGTTTCACCAGATTCTGGCGGAAGCTGCCGCT
AACCCGGTGCTTCTTGAGATGGCAGCGGCTTTGTACGAAGGGTTTGCCAAGAGTCGTGAAGACGGTGTGCAGTCTTTTGA
GCGCCAGCAGGCATCGCTGAAGGCTCATAGAGAAATTGTGGCTGCAGTCAGGGCGGGGGATTCACGGAAAGCTGAAAGAG
CCATGCACAGCCACCTGACAGATGTGGCCCGGCGGATATGTTCTGCATGCCGCTAG

Upstream 100 bases:

>100_bases
TTTTTGTCTTTCTGCCGCTTTCAATACCGCCTCCTGAATTGACAGCTTAGATGCATCGGTGTATTTATAAAGTGGTCAGA
CCAATTTGGAGGTGTATCAG

Downstream 100 bases:

>100_bases
GTTGTTGCAGGTTGGCGGGACAGATTGCAGAAATTTTATGAATGTGATGTCAGCATGTTGTGTGCATATCTGTGTGCAGA
GCATGCGTGCAGGCATAAGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MVAESAPRTSVAAEVAEKIRRMIDEGQMLPGERLPAERKLAGLFNVSRASVREGIKLLAESGRLLSRQGSGTYVRERCAE
NSGRTLVQTVLNGGYSLQDVIAVRLLLEPEIAALAARNGGAAVAARLEAVLAEQEIAIGSKDYSGSADVLFHQILAEAAA
NPVLLEMAAALYEGFAKSREDGVQSFERQQASLKAHREIVAAVRAGDSRKAERAMHSHLTDVARRICSACR

Sequences:

>Translated_231_residues
MVAESAPRTSVAAEVAEKIRRMIDEGQMLPGERLPAERKLAGLFNVSRASVREGIKLLAESGRLLSRQGSGTYVRERCAE
NSGRTLVQTVLNGGYSLQDVIAVRLLLEPEIAALAARNGGAAVAARLEAVLAEQEIAIGSKDYSGSADVLFHQILAEAAA
NPVLLEMAAALYEGFAKSREDGVQSFERQQASLKAHREIVAAVRAGDSRKAERAMHSHLTDVARRICSACR
>Mature_231_residues
MVAESAPRTSVAAEVAEKIRRMIDEGQMLPGERLPAERKLAGLFNVSRASVREGIKLLAESGRLLSRQGSGTYVRERCAE
NSGRTLVQTVLNGGYSLQDVIAVRLLLEPEIAALAARNGGAAVAARLEAVLAEQEIAIGSKDYSGSADVLFHQILAEAAA
NPVLLEMAAALYEGFAKSREDGVQSFERQQASLKAHREIVAAVRAGDSRKAERAMHSHLTDVARRICSACR

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=234, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790780, Length=225, Percent_Identity=31.1111111111111, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786303, Length=211, Percent_Identity=33.175355450237, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789621, Length=228, Percent_Identity=28.5087719298246, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994961, Length=212, Percent_Identity=29.7169811320755, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI48994955, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787821, Length=219, Percent_Identity=27.8538812785388, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24793; Mature: 24793

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAESAPRTSVAAEVAEKIRRMIDEGQMLPGERLPAERKLAGLFNVSRASVREGIKLLAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SGRLLSRQGSGTYVRERCAENSGRTLVQTVLNGGYSLQDVIAVRLLLEPEIAALAARNGG
CCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCC
AAVAARLEAVLAEQEIAIGSKDYSGSADVLFHQILAEAAANPVLLEMAAALYEGFAKSRE
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DGVQSFERQQASLKAHREIVAAVRAGDSRKAERAMHSHLTDVARRICSACR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVAESAPRTSVAAEVAEKIRRMIDEGQMLPGERLPAERKLAGLFNVSRASVREGIKLLAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SGRLLSRQGSGTYVRERCAENSGRTLVQTVLNGGYSLQDVIAVRLLLEPEIAALAARNGG
CCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCC
AAVAARLEAVLAEQEIAIGSKDYSGSADVLFHQILAEAAANPVLLEMAAALYEGFAKSRE
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DGVQSFERQQASLKAHREIVAAVRAGDSRKAERAMHSHLTDVARRICSACR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]