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The map label for this gene is dhaL [H]

Identifier: 78356226

GI number: 78356226

Start: 1206698

End: 1207330

Strand: Direct

Name: dhaL [H]

Synonym: Dde_1179

Alternate gene names: 78356226

Gene position: 1206698-1207330 (Clockwise)

Preceding gene: 78356225

Following gene: 78356227

Centisome position: 32.35

GC content: 60.19

Gene sequence:

>633_bases
ATGCAGATGACCAAGGAACAGGTGCTGGACTGGCTTAAGGCTCTGGCCGCAGAATATAAGGCGCAGAAGGAATATCTGAC
CGGTCTCGACGCCGCCATAGGTGACGCGGATCACGGAATCAACATGGATCGCGGTTTTGGCAAGGTGCTTGAAAAACTGC
CTTCCATGGAAGCAAAGGACATCGGCGCCATTTTGAAGGATACCGGAATGACGCTGCTTTCCAGTGTCGGCGGGGCCAGC
GGGCCGCTGTACGGAACATTTTTTATGAAAGCGGGCATGGCGCTGGCCGGAGCGGAAACGCTGGACGAAGCGGCCATGCA
GAAGCTGCTGGAAAGCGGTGTGGAGGGCATTGTATCGCGCGGGCGTCCCGTGGAAGGGGACAAAACCATGTACGATATCT
GGAAGCCCGCGCTTGATGCGTACACACAGGCAGTGCAGGCAGGCGCCGCGCTTGATGCCGCACTTGATGCCGCGGTGGCG
GCCGCGGAAAAAGGTCTGGAAGCCACCGTGCCCATGCAGGCCCGCAAGGGGCGCGCAAGCTATCTGGGCGAACGCAGCAT
CGGTCACAAAGATCCCGGCGGGGCTTCCTCGTGCATGATGCTCGGCGCGTTGCGTCAGAGTATCGGGGGATAG

Upstream 100 bases:

>100_bases
AAATCTGATAACAACATATCCGCCTGCGGGGTCTGCACGGCCCCGCGGCGCAAAGCATATACCGGCCGGCATCGCTGCCG
GACCGCCGGAGATTTTCCGC

Downstream 100 bases:

>100_bases
CCGCATGGTCGGCCTTGTAATTGTTTCTCACAGTGCCGTTCTGGCAGAAGGAGTGCGCGAGCTTGCCCTGCAGATGACGC
AGGGCAGGGTGCGTATTGCT

Product: DAK2 domain-containing protein

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MQMTKEQVLDWLKALAAEYKAQKEYLTGLDAAIGDADHGINMDRGFGKVLEKLPSMEAKDIGAILKDTGMTLLSSVGGAS
GPLYGTFFMKAGMALAGAETLDEAAMQKLLESGVEGIVSRGRPVEGDKTMYDIWKPALDAYTQAVQAGAALDAALDAAVA
AAEKGLEATVPMQARKGRASYLGERSIGHKDPGGASSCMMLGALRQSIGG

Sequences:

>Translated_210_residues
MQMTKEQVLDWLKALAAEYKAQKEYLTGLDAAIGDADHGINMDRGFGKVLEKLPSMEAKDIGAILKDTGMTLLSSVGGAS
GPLYGTFFMKAGMALAGAETLDEAAMQKLLESGVEGIVSRGRPVEGDKTMYDIWKPALDAYTQAVQAGAALDAALDAAVA
AAEKGLEATVPMQARKGRASYLGERSIGHKDPGGASSCMMLGALRQSIGG
>Mature_210_residues
MQMTKEQVLDWLKALAAEYKAQKEYLTGLDAAIGDADHGINMDRGFGKVLEKLPSMEAKDIGAILKDTGMTLLSSVGGAS
GPLYGTFFMKAGMALAGAETLDEAAMQKLLESGVEGIVSRGRPVEGDKTMYDIWKPALDAYTQAVQAGAALDAALDAAVA
AAEKGLEATVPMQARKGRASYLGERSIGHKDPGGASSCMMLGALRQSIGG

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=203, Percent_Identity=33.0049261083744, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787449, Length=204, Percent_Identity=50.9803921568627, Blast_Score=218, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6323570, Length=208, Percent_Identity=25, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 21902; Mature: 21902

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMTKEQVLDWLKALAAEYKAQKEYLTGLDAAIGDADHGINMDRGFGKVLEKLPSMEAKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHH
IGAILKDTGMTLLSSVGGASGPLYGTFFMKAGMALAGAETLDEAAMQKLLESGVEGIVSR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRPVEGDKTMYDIWKPALDAYTQAVQAGAALDAALDAAVAAAEKGLEATVPMQARKGRAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
YLGERSIGHKDPGGASSCMMLGALRQSIGG
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQMTKEQVLDWLKALAAEYKAQKEYLTGLDAAIGDADHGINMDRGFGKVLEKLPSMEAKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHH
IGAILKDTGMTLLSSVGGASGPLYGTFFMKAGMALAGAETLDEAAMQKLLESGVEGIVSR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRPVEGDKTMYDIWKPALDAYTQAVQAGAALDAALDAAVAAAEKGLEATVPMQARKGRAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
YLGERSIGHKDPGGASSCMMLGALRQSIGG
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]