Click here to switch to the map view.

The map label for this gene is yhdR [H]

Identifier: 78356150

GI number: 78356150

Start: 1131201

End: 1132586

Strand: Direct

Name: yhdR [H]

Synonym: Dde_1103

Alternate gene names: 78356150

Gene position: 1131201-1132586 (Clockwise)

Preceding gene: 78356131

Following gene: 78356155

Centisome position: 30.33

GC content: 57.94

Gene sequence:

>1386_bases
GTGCGCGCGGCCGTATTTTTCACTATAGCGTGTAGTGGCGGTCTGTTCAAGAATTGTACATTAATCAGTCTGCCTGACGT
GCGCGGTGCTGCGCGTGCTGGACAACGGCTGCGGTATTGCCTATCGGAAACGGACCGACCCGAAAATAACAGCCGTCGGC
GAACGGCCAAAGCATTACGACAGCACGAGGTGGACATGTCGCTTATTTCCGCAGAAATTGCAGGATATCTGGAAAAATCA
TCGTGGATCCGCAAGATGTTCGAGGCTGGAATCGCTCTTAAAAAACAATACGGCGAGCAGGCTGTGTGTGATTTCAGTCT
GGGCAACCCCGACCTGCCCGCGCCGCCTGCGGTGGGCGATGCTTTGCGTACCATGGCTGAAAATGCCGGAAAGCCTTTTG
CTTTCGGCTATATGCCCAACGGCGGTTTTCAGTGGGCCCGTGAAGCTCTTGCCGGGCAGGTATCCGCAGAACAGGGTATG
CCCGTTGACGCAGGCGATCTGCTGCTTTCCTGCGGAGCCGCGGGGGCGCTCAATGCGTTTTTCCGCGCTGTGCTGGAACC
GGGCGACGAAGTGCTGGCGGTGGCTCCTTATTTTGTGGAGTACGGTTTTTATGTGTCCAACCATCAGGGTGTGTTTAAAA
CGGCCATGAGCCGTCCGGAAACCTTTGAGCTGGACATTGAGGCCGTGGAAGCCCGCATAACTCCGAAAACACGGGCGCTG
ATCATCAATTCGCCCAACAATCCCACCGGGGTTGTCTACAGCCGTGAAGAACTGGAAGCCCTTGCGGCACTTCTTGAGCG
CAAGAGCCGCGAAAACGGCCGTCCCGTCTATCTCATCGCGGACGAACCTTACCGTTTTCTGTCGTTTGACGGTGTAAAGG
TGCCCAGCGTACTGCCGCTGTATCCTTTCAGTGTGGTAGTGAACAGTTTTTCCAAAAACCTGTCTCTGGCCGGCGAGCGT
TTGGGGTACATCTGCCTTTCGCCTCTCATGGAGAACCGCGCGGAGCTGATGGCCGCGCTGACGCTGACAAACCGCATTCT
CGGTTTTGTGAATCCGCCGGTTATCGGCCAGCACGTCATGGCGCATGCGCTGGGGTCGCAGGTTGACGTGGGCGTGTACG
CGCAGCGCCGTGATGCCATGGCCGAGGTGCTTTCAGGCGCCGGATACCAGTTCTCCATGCCCAAGGGCGCGTTTTACTTT
TTCCCCAAGGCGCCGGGTGGCGACGATGTGGAGTTCTGCCGTGTGCTGATGGAGGAAAAGGTGCTCGCGGTACCCGGATC
AGGGTTCGGCGGCCCCGGTTATTTCAGGCTGACATTCTGCGTGGATGAGGAAGTCATCCGCCGCAGTGCCGGCGGGTTTG
CGCGGGCCATGGCTCATTTCGCGTAG

Upstream 100 bases:

>100_bases
GCGGGCCGTTACTCCCGGCAGCCAGTGCATAAAAGGGAAAAAGGCTGCGATGCCCGTTTTCATGTGTACATGACTCCGTG
ATGTATGATGTCCGGCCACG

Downstream 100 bases:

>100_bases
CCGTCCGCCGGTGCGTGCCCGCAGTGCGCGCCGGTCTGCGCTGTATGCCGGTACAGGCAATAACGGCGCCGTCTCACGGG
AGGCGGCGCTTTTTTTGCGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRAAVFFTIACSGGLFKNCTLISLPDVRGAARAGQRLRYCLSETDRPENNSRRRTAKALRQHEVDMSLISAEIAGYLEKS
SWIRKMFEAGIALKKQYGEQAVCDFSLGNPDLPAPPAVGDALRTMAENAGKPFAFGYMPNGGFQWAREALAGQVSAEQGM
PVDAGDLLLSCGAAGALNAFFRAVLEPGDEVLAVAPYFVEYGFYVSNHQGVFKTAMSRPETFELDIEAVEARITPKTRAL
IINSPNNPTGVVYSREELEALAALLERKSRENGRPVYLIADEPYRFLSFDGVKVPSVLPLYPFSVVVNSFSKNLSLAGER
LGYICLSPLMENRAELMAALTLTNRILGFVNPPVIGQHVMAHALGSQVDVGVYAQRRDAMAEVLSGAGYQFSMPKGAFYF
FPKAPGGDDVEFCRVLMEEKVLAVPGSGFGGPGYFRLTFCVDEEVIRRSAGGFARAMAHFA

Sequences:

>Translated_461_residues
MRAAVFFTIACSGGLFKNCTLISLPDVRGAARAGQRLRYCLSETDRPENNSRRRTAKALRQHEVDMSLISAEIAGYLEKS
SWIRKMFEAGIALKKQYGEQAVCDFSLGNPDLPAPPAVGDALRTMAENAGKPFAFGYMPNGGFQWAREALAGQVSAEQGM
PVDAGDLLLSCGAAGALNAFFRAVLEPGDEVLAVAPYFVEYGFYVSNHQGVFKTAMSRPETFELDIEAVEARITPKTRAL
IINSPNNPTGVVYSREELEALAALLERKSRENGRPVYLIADEPYRFLSFDGVKVPSVLPLYPFSVVVNSFSKNLSLAGER
LGYICLSPLMENRAELMAALTLTNRILGFVNPPVIGQHVMAHALGSQVDVGVYAQRRDAMAEVLSGAGYQFSMPKGAFYF
FPKAPGGDDVEFCRVLMEEKVLAVPGSGFGGPGYFRLTFCVDEEVIRRSAGGFARAMAHFA
>Mature_461_residues
MRAAVFFTIACSGGLFKNCTLISLPDVRGAARAGQRLRYCLSETDRPENNSRRRTAKALRQHEVDMSLISAEIAGYLEKS
SWIRKMFEAGIALKKQYGEQAVCDFSLGNPDLPAPPAVGDALRTMAENAGKPFAFGYMPNGGFQWAREALAGQVSAEQGM
PVDAGDLLLSCGAAGALNAFFRAVLEPGDEVLAVAPYFVEYGFYVSNHQGVFKTAMSRPETFELDIEAVEARITPKTRAL
IINSPNNPTGVVYSREELEALAALLERKSRENGRPVYLIADEPYRFLSFDGVKVPSVLPLYPFSVVVNSFSKNLSLAGER
LGYICLSPLMENRAELMAALTLTNRILGFVNPPVIGQHVMAHALGSQVDVGVYAQRRDAMAEVLSGAGYQFSMPKGAFYF
FPKAPGGDDVEFCRVLMEEKVLAVPGSGFGGPGYFRLTFCVDEEVIRRSAGGFARAMAHFA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI95147551, Length=410, Percent_Identity=24.390243902439, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI169881279, Length=410, Percent_Identity=24.390243902439, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=23.5142118863049, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=23.5142118863049, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881281, Length=264, Percent_Identity=25.3787878787879, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=28.3854166666667, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=28.125, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=26.4150943396226, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=27.5401069518717, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=366, Percent_Identity=27.3224043715847, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=25.8241758241758, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=25.8241758241758, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=327, Percent_Identity=23.2415902140673, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=372, Percent_Identity=24.7311827956989, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646114, Length=372, Percent_Identity=24.7311827956989, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573067, Length=372, Percent_Identity=24.7311827956989, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573065, Length=372, Percent_Identity=24.7311827956989, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=342, Percent_Identity=28.0701754385965, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 50155; Mature: 50155

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAVFFTIACSGGLFKNCTLISLPDVRGAARAGQRLRYCLSETDRPENNSRRRTAKALR
CCEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
QHEVDMSLISAEIAGYLEKSSWIRKMFEAGIALKKQYGEQAVCDFSLGNPDLPAPPAVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHH
ALRTMAENAGKPFAFGYMPNGGFQWAREALAGQVSAEQGMPVDAGDLLLSCGAAGALNAF
HHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHCCCCHHHHHH
FRAVLEPGDEVLAVAPYFVEYGFYVSNHQGVFKTAMSRPETFELDIEAVEARITPKTRAL
HHHHHCCCCCEEEECHHHHHHCCEEECCCCHHHHHHCCCCEEEEEHHHHEEEECCCEEEE
IINSPNNPTGVVYSREELEALAALLERKSRENGRPVYLIADEPYRFLSFDGVKVPSVLPL
EEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCC
YPFSVVVNSFSKNLSLAGERLGYICLSPLMENRAELMAALTLTNRILGFVNPPVIGQHVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHALGSQVDVGVYAQRRDAMAEVLSGAGYQFSMPKGAFYFFPKAPGGDDVEFCRVLMEEK
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHCC
VLAVPGSGFGGPGYFRLTFCVDEEVIRRSAGGFARAMAHFA
EEECCCCCCCCCCEEEEEEEECHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MRAAVFFTIACSGGLFKNCTLISLPDVRGAARAGQRLRYCLSETDRPENNSRRRTAKALR
CCEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
QHEVDMSLISAEIAGYLEKSSWIRKMFEAGIALKKQYGEQAVCDFSLGNPDLPAPPAVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHH
ALRTMAENAGKPFAFGYMPNGGFQWAREALAGQVSAEQGMPVDAGDLLLSCGAAGALNAF
HHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHCCCCHHHHHH
FRAVLEPGDEVLAVAPYFVEYGFYVSNHQGVFKTAMSRPETFELDIEAVEARITPKTRAL
HHHHHCCCCCEEEECHHHHHHCCEEECCCCHHHHHHCCCCEEEEEHHHHEEEECCCEEEE
IINSPNNPTGVVYSREELEALAALLERKSRENGRPVYLIADEPYRFLSFDGVKVPSVLPL
EEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCC
YPFSVVVNSFSKNLSLAGERLGYICLSPLMENRAELMAALTLTNRILGFVNPPVIGQHVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHALGSQVDVGVYAQRRDAMAEVLSGAGYQFSMPKGAFYFFPKAPGGDDVEFCRVLMEEK
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHCC
VLAVPGSGFGGPGYFRLTFCVDEEVIRRSAGGFARAMAHFA
EEECCCCCCCCCCEEEEEEEECHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]