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The map label for this gene is manZ [C]

Identifier: 78356138

GI number: 78356138

Start: 1121594

End: 1122373

Strand: Reverse

Name: manZ [C]

Synonym: Dde_1091

Alternate gene names: 78356138

Gene position: 1122373-1121594 (Counterclockwise)

Preceding gene: 78356139

Following gene: 78356137

Centisome position: 30.09

GC content: 60.64

Gene sequence:

>780_bases
ATGGCACTGGACGCACGAACCCTGCTACGCTGTTTTCTGCGCACCTACACAGTGGGGGCCGCATTCAACACGCGCGGCAT
GCAGAATATCGGGTTGGTGCATGCCATGGAACCCGGCCTTGCGGCCATATACCCCGATCCGGTAAAACGGCGCGAGGCCC
GCAAAAAATATATCCGGCACTACAATACCCATCCTTTCTGGACACCGCTGCTGGTGGGTACGTTTCTTTCACTGGAAGCG
GGCATAGCCGCGCAGACCTTCCCGCCGCAGATTCTGCGCAACCTGAAGGATACCACGGCCTATACCCTGTCAGCCATCGG
CGACTCCGTTTTCGGCGGCACCATGCTGGTATCGTGGTCGCTGGCCACATGCAGTCTGCTGGTGGCGGGTTACCAGTCGG
CGGCGTTTGCTCTGGGGCTTTTTCTGTTCACGGCGCTGCAGGCGTTCAAGCTGTTCACCTTCATCGCCGGACTGCGCGAA
GGGCTTAAAGTGCTCAACCGGCTGCGCAACTGGAACCTGATAAACTGGGGTGAAAGGCTGAAGTCGGGTAATGCTGTGCT
GGCGGCGGTGCTGCTGTGGCAGCTGTTTCCCGCGCATGACCGCCCCGCCCTGTGGGCTGCGGCATGCGCCGCGCTGGGAC
TGTTCGCCGCGCTGGTGGGCCGTCTGCACATGTCGCGCATGCTGCTGCTGTTTATTTTTACGGCTGTTATACTGGCACTG
CCGTTCGCCACGGCGTATGTTCCCGTGGAGTGGCATCTTTTCTGGCAGCCCGCTGACTGA

Upstream 100 bases:

>100_bases
GAGGCAAACCGCGTGAAGTCGCCCGCAGAACAGCGGACCGGGCTCCGGGCTGGAGCGTGAAAGAAATTTACGAAATCATG
AAGGATTTACGGACCTGACC

Downstream 100 bases:

>100_bases
CGCATACAACAAACGTTCCGGCACGGCCGGAAAACATATACGCATACAATGCTGGAGGAACCTCTCCCGTGCAGGAAGAG
ATTCGTGAAATAGAAGACGG

Product: PTS system transporter subunit IID

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Phosphotransferase System IID Component; PTS System IID Component; Pts System Mannose/Fructose/Sorbose Family IId Component; PTS System Transporter Subunit IID

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MALDARTLLRCFLRTYTVGAAFNTRGMQNIGLVHAMEPGLAAIYPDPVKRREARKKYIRHYNTHPFWTPLLVGTFLSLEA
GIAAQTFPPQILRNLKDTTAYTLSAIGDSVFGGTMLVSWSLATCSLLVAGYQSAAFALGLFLFTALQAFKLFTFIAGLRE
GLKVLNRLRNWNLINWGERLKSGNAVLAAVLLWQLFPAHDRPALWAAACAALGLFAALVGRLHMSRMLLLFIFTAVILAL
PFATAYVPVEWHLFWQPAD

Sequences:

>Translated_259_residues
MALDARTLLRCFLRTYTVGAAFNTRGMQNIGLVHAMEPGLAAIYPDPVKRREARKKYIRHYNTHPFWTPLLVGTFLSLEA
GIAAQTFPPQILRNLKDTTAYTLSAIGDSVFGGTMLVSWSLATCSLLVAGYQSAAFALGLFLFTALQAFKLFTFIAGLRE
GLKVLNRLRNWNLINWGERLKSGNAVLAAVLLWQLFPAHDRPALWAAACAALGLFAALVGRLHMSRMLLLFIFTAVILAL
PFATAYVPVEWHLFWQPAD
>Mature_258_residues
ALDARTLLRCFLRTYTVGAAFNTRGMQNIGLVHAMEPGLAAIYPDPVKRREARKKYIRHYNTHPFWTPLLVGTFLSLEAG
IAAQTFPPQILRNLKDTTAYTLSAIGDSVFGGTMLVSWSLATCSLLVAGYQSAAFALGLFLFTALQAFKLFTFIAGLREG
LKVLNRLRNWNLINWGERLKSGNAVLAAVLLWQLFPAHDRPALWAAACAALGLFAALVGRLHMSRMLLLFIFTAVILALP
FATAYVPVEWHLFWQPAD

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG3716

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 28728; Mature: 28597

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS51108 PTS_EIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDARTLLRCFLRTYTVGAAFNTRGMQNIGLVHAMEPGLAAIYPDPVKRREARKKYIRH
CCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCHHEECCCCCEEECCCHHHHHHHHHHHHHH
YNTHPFWTPLLVGTFLSLEAGIAAQTFPPQILRNLKDTTAYTLSAIGDSVFGGTMLVSWS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LATCSLLVAGYQSAAFALGLFLFTALQAFKLFTFIAGLREGLKVLNRLRNWNLINWGERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
KSGNAVLAAVLLWQLFPAHDRPALWAAACAALGLFAALVGRLHMSRMLLLFIFTAVILAL
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFATAYVPVEWHLFWQPAD
HHHHHEEEEEEEEEEECCC
>Mature Secondary Structure 
ALDARTLLRCFLRTYTVGAAFNTRGMQNIGLVHAMEPGLAAIYPDPVKRREARKKYIRH
CCCHHHHHHHHHHHHHHCCHHCCCCCCCCCHHEECCCCCEEECCCHHHHHHHHHHHHHH
YNTHPFWTPLLVGTFLSLEAGIAAQTFPPQILRNLKDTTAYTLSAIGDSVFGGTMLVSWS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LATCSLLVAGYQSAAFALGLFLFTALQAFKLFTFIAGLREGLKVLNRLRNWNLINWGERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
KSGNAVLAAVLLWQLFPAHDRPALWAAACAALGLFAALVGRLHMSRMLLLFIFTAVILAL
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFATAYVPVEWHLFWQPAD
HHHHHEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA