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The map label for this gene is ribB

Identifier: 78356097

GI number: 78356097

Start: 1078352

End: 1079011

Strand: Direct

Name: ribB

Synonym: Dde_1050

Alternate gene names: 78356097

Gene position: 1078352-1079011 (Clockwise)

Preceding gene: 78356095

Following gene: 78356100

Centisome position: 28.91

GC content: 58.79

Gene sequence:

>660_bases
ATGTCTGCAAAAGAATCTTTGCTTACCGGAACATTTGAAGAACGTGTCGAAGCTGCTCTGGATGCCCTGCGCAGGGGCCA
CGGCGTGCTGGTGACCGATGATGAAGACCGCGAAAATGAAGGTGATCTGATTTTTGCGGCCGAAACGCTGTCAGACAGCC
AGATGGCCATGCTCATCAGGGAATGCAGCGGCATAGTGTGCCTGTGTCTGACAGATGAAAAAGTGCGCGCGCTGGGACTG
CCCATGATGGTGGAAAACAACTCCAGCCAGTATCAGACGGCGTTCACTGTTTCCATCGAAGCCTCCTGCGGCGTGTCCAC
CGGAGTTTCGGCAGCGGACAGGGTGTGCACCATTCAGGCTGCCATAGCCGATGATGCCTGCCCGTCGGACCTGTGCCGTC
CGGGCCACGTGTTTCCGTTGCGGGCCCGTCCCGGCGGAGTGCTGGAGCGCAGAGGGCACACCGAGGCCACCGTGGACCTG
ATGCGCCTTGCAGGGCTGAAACCCTGCGGCGTGCTGTGCGAAGTGACCAACCCCGACGGTACCATGGCCCGTCTGCCGCA
GATTGTGGATTTCGGCAGAAAACATGATATGGTGGTGCTTACCGTGGATGATCTGGTACGGTACCGTGAGATGAAGGAAA
ACAAATCGGCCGCGGCGTAA

Upstream 100 bases:

>100_bases
CTGTGACAGTCCTTTCGCCTGTGCCGCGTGTTGCGGTGCTGGCTCACTGCCTGTTCCCACGCCCTTGTTCCGTCTTTTTT
CACCAGAAGGGAGTGGTATA

Downstream 100 bases:

>100_bases
GCCCGCCCCGCCGGCCGGTCTGTGCCGGAACAGCCGGAGATTTTCAGACGGAGCACCGATAAGTCGGCATGGTGCTTCCT
GCAAACGGAAAAAGGCCGCC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSAKESLLTGTFEERVEAALDALRRGHGVLVTDDEDRENEGDLIFAAETLSDSQMAMLIRECSGIVCLCLTDEKVRALGL
PMMVENNSSQYQTAFTVSIEASCGVSTGVSAADRVCTIQAAIADDACPSDLCRPGHVFPLRARPGGVLERRGHTEATVDL
MRLAGLKPCGVLCEVTNPDGTMARLPQIVDFGRKHDMVVLTVDDLVRYREMKENKSAAA

Sequences:

>Translated_219_residues
MSAKESLLTGTFEERVEAALDALRRGHGVLVTDDEDRENEGDLIFAAETLSDSQMAMLIRECSGIVCLCLTDEKVRALGL
PMMVENNSSQYQTAFTVSIEASCGVSTGVSAADRVCTIQAAIADDACPSDLCRPGHVFPLRARPGGVLERRGHTEATVDL
MRLAGLKPCGVLCEVTNPDGTMARLPQIVDFGRKHDMVVLTVDDLVRYREMKENKSAAA
>Mature_218_residues
SAKESLLTGTFEERVEAALDALRRGHGVLVTDDEDRENEGDLIFAAETLSDSQMAMLIRECSGIVCLCLTDEKVRALGLP
MMVENNSSQYQTAFTVSIEASCGVSTGVSAADRVCTIQAAIADDACPSDLCRPGHVFPLRARPGGVLERRGHTEATVDLM
RLAGLKPCGVLCEVTNPDGTMARLPQIVDFGRKHDMVVLTVDDLVRYREMKENKSAAA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=216, Percent_Identity=64.3518518518518, Blast_Score=285, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=41.7910447761194, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_DESDG (Q313P5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387546.1
- ProteinModelPortal:   Q313P5
- SMR:   Q313P5
- STRING:   Q313P5
- GeneID:   3755475
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1050
- NMPDR:   fig|207559.3.peg.879
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- BioCyc:   DDES207559:DDE_1050-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23661; Mature: 23530

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKESLLTGTFEERVEAALDALRRGHGVLVTDDEDRENEGDLIFAAETLSDSQMAMLIR
CCCHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHH
ECSGIVCLCLTDEKVRALGLPMMVENNSSQYQTAFTVSIEASCGVSTGVSAADRVCTIQA
HCCCEEEEEECCCCHHHHCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHEEEEEE
AIADDACPSDLCRPGHVFPLRARPGGVLERRGHTEATVDLMRLAGLKPCGVLCEVTNPDG
ECCCCCCCHHHCCCCCEEEECCCCCCCHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIVDFGRKHDMVVLTVDDLVRYREMKENKSAAA
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAKESLLTGTFEERVEAALDALRRGHGVLVTDDEDRENEGDLIFAAETLSDSQMAMLIR
CCHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHH
ECSGIVCLCLTDEKVRALGLPMMVENNSSQYQTAFTVSIEASCGVSTGVSAADRVCTIQA
HCCCEEEEEECCCCHHHHCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHEEEEEE
AIADDACPSDLCRPGHVFPLRARPGGVLERRGHTEATVDLMRLAGLKPCGVLCEVTNPDG
ECCCCCCCHHHCCCCCEEEECCCCCCCHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIVDFGRKHDMVVLTVDDLVRYREMKENKSAAA
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA