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The map label for this gene is mraY

Identifier: 78356086

GI number: 78356086

Start: 1066761

End: 1067837

Strand: Direct

Name: mraY

Synonym: Dde_1039

Alternate gene names: 78356086

Gene position: 1066761-1067837 (Clockwise)

Preceding gene: 78356085

Following gene: 78356087

Centisome position: 28.6

GC content: 56.45

Gene sequence:

>1077_bases
ATGCTGTATCATTTCCTGTATCCGCTCAGCGCGGAACTGCCGCTGCTCAACGTGTTCCGGTACATCACATTCCGTTCGGT
GTGGGCGCTGCTGACGGCGCTGCTCATCACCATTTTCATCGGCCCGCGGTTTATCCGCTGGCTCAAGCGCGTCAAATGCG
GGCAGTACATTCAGGAAGAAGTCTCCTGCCATGTGCAGAAAGCGGGTACCCCCACCATGGGCGGGCTGCTCATCGGCTTC
AGCCTTATCATCAGCGTGCTGTTGTGGGGCGACCTGACCAACGTGTACCTGTGGCTGGTCATGCTGGTGTTTACCGGCTT
CGGTCTGGTGGGCTTTCTGGATGATTATACCAAGCTGCGGCGCAAGACCAATCAGGGGCTTACCGCCCGTTCCAAATTTT
TGTGGCAGATGGTCATAGCGGCTGTGGCCATGTATTTTCTGGTCAAGGAACCGGCGTACTCCACCGTACTTTCGTTTCCG
TTTTTCAAAAATCTGCAGCCGGACCTCGGCTGGTTCTACATTCCGTTTGCCATGATTGTGCTGGTCGGTTCGTCCAACGG
GGTCAACCTGACAGACGGTATGGACGGGCTGGCCATAGGGCCCACCGTGGTGGCGGGAATCGTTTTTTCCATTTTCATCT
ACATTGCAGGACACAGCCAGATAGCCGGATACCTGCAGGTGCCCTATGTGCCCGGCATGGGTGAGGTGACCGTTTTCTGC
GGCGCACTTATCGGTGCCGGTCTGGGTTTTCTGTGGTTCAACGCCTACCCCGCGCAGGTGTTCATGGGCGACGTGGGTTC
GCTGAGTCTGGGCGGCGCGCTGGGTTTTCTGGCTGTGCTGTGCAAACAGGAACTCATCATGCTGGTGGCCGGCGGGCTTT
TTGTTCTCGAATCGCTCTCGGTCATTCTGCAGGTGGGGTATTTCCGCATGACCGGAGGCAAGCGCATTTTCCGCATGGCT
CCGCTGCATCACCATTTCGAACTGAAAGGCATTCCCGAGTCAAAAATCATTATCCGCTTCTGGATAATGTCCATCGTGTT
CGGACTGATGGCGCTTTCGGTGCTCAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
CACGGTCTTGTTTAAAGGATCGCGCAGCAACAGGCTGGAGACGTTTGCCGAAGCCTTCTGCAGTGCAGTCCAGAACGGTC
AGGAAGGGAGATAACCGCAT

Downstream 100 bases:

>100_bases
AGGGGAAGACAGATATGCATACCGTTATACCGCATACACACGACACGCCTGCCGCCGCACCGGTACGTTCCGGCGCTGTG
GCCGTGGTGGTGGGCACCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEEVSCHVQKAGTPTMGGLLIGF
SLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLRRKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFP
FFKNLQPDLGWFYIPFAMIVLVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFC
GALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLSVILQVGYFRMTGGKRIFRMA
PLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR

Sequences:

>Translated_358_residues
MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEEVSCHVQKAGTPTMGGLLIGF
SLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLRRKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFP
FFKNLQPDLGWFYIPFAMIVLVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFC
GALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLSVILQVGYFRMTGGKRIFRMA
PLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR
>Mature_358_residues
MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEEVSCHVQKAGTPTMGGLLIGF
SLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLRRKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFP
FFKNLQPDLGWFYIPFAMIVLVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFC
GALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLSVILQVGYFRMTGGKRIFRMA
PLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=346, Percent_Identity=52.6011560693642, Blast_Score=349, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_DESDG (Q313Q6)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387535.1
- STRING:   Q313Q6
- GeneID:   3755503
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1039
- NMPDR:   fig|207559.3.peg.868
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   DDES207559:DDE_1039-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39776; Mature: 39776

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x109d2628)-; HASH(0x101894e4)-; HASH(0xf1972b8)-; HASH(0xfd1978c)-; HASH(0xff655f4)-; HASH(0x106d8abc)-; HASH(0x10c885b8)-; HASH(0x10c7582c)-; HASH(0x10c88558)-; HASH(0xf105a94)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEE
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSCHVQKAGTPTMGGLLIGFSLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFPFFKNLQPDLGWFYIPFAMIV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHCCCCCCCHHHHHHHHHH
LVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFC
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCHHHHHH
GALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLS
HHHHHCCHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILQVGYFRMTGGKRIFRMAPLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR
HHHHHHHHEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEE
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSCHVQKAGTPTMGGLLIGFSLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFPFFKNLQPDLGWFYIPFAMIV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHCCCCCCCHHHHHHHHHH
LVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFC
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCHHHHHH
GALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLS
HHHHHCCHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILQVGYFRMTGGKRIFRMAPLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR
HHHHHHHHEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA