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The map label for this gene is msrB2 [H]

Identifier: 78356050

GI number: 78356050

Start: 1027531

End: 1028091

Strand: Reverse

Name: msrB2 [H]

Synonym: Dde_1003

Alternate gene names: 78356050

Gene position: 1028091-1027531 (Counterclockwise)

Preceding gene: 78356051

Following gene: 78356049

Centisome position: 27.56

GC content: 54.55

Gene sequence:

>561_bases
GTGCCCTGCCTGCCCGTACCATTCTTTCCTCCTCGGATTCTGGACTTACCGACCCGCGTGCTTATTGCCATAGAGTATAC
GCATCACCCCCTAGCACCGCAGGAGAATCCCATGCCGCAAAAATACCGCAAAACTCCGGAGGCACTGGCCGCACTGACAG
ATGAGCAGCGCAGGGTAACGCAGGAAAACGGCACTGAACGTCCGTTCAGCAACGCTTTTCACGACCACACCGCAGCAGGA
CTGTATGTGGACATCGTTTCCGGCGAACCGCTGTTTTCATCACTGGATAAATTTGATTCCGGCTGCGGGTGGCCCAGCTT
CAGCAGGCCTGTGGAACTGAATATAGTGGAGAAAAAAGATACAAGTCATGGTCTTGTCCGCACAGAAGTACGCTCGAAAC
ATGCGGACAGTCATCTGGGACATGTGTTCACAGACGGGCCGGAGCATCTGACAGGCCTGCGGTACTGTATCAATTCAGCC
GCACTGCGTTTTATTCCGGCGGACAAGCTGGAAGAGGAAGGGTACGGCGAATATGCACACCTTTTCACCACACGGGAGTA
G

Upstream 100 bases:

>100_bases
AGTTCGAATCTCTCCCTCTCCGCCATTCTGCAATATTCAAGGGATCTTACGATCCCTTTTTTTTATTGCCTGCGCTACGC
CGGCTGTTCCCCTGAACCAA

Downstream 100 bases:

>100_bases
CCCATGGAAACAGTAACCGAACGTGCAGTACTGGCCGGAGGATGCTTCTGGGGAATGCAGGAACTCATCAGAAAGCTGCC
CGGCGTGCTTGCCACGCGCA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 2 [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MPCLPVPFFPPRILDLPTRVLIAIEYTHHPLAPQENPMPQKYRKTPEALAALTDEQRRVTQENGTERPFSNAFHDHTAAG
LYVDIVSGEPLFSSLDKFDSGCGWPSFSRPVELNIVEKKDTSHGLVRTEVRSKHADSHLGHVFTDGPEHLTGLRYCINSA
ALRFIPADKLEEEGYGEYAHLFTTRE

Sequences:

>Translated_186_residues
MPCLPVPFFPPRILDLPTRVLIAIEYTHHPLAPQENPMPQKYRKTPEALAALTDEQRRVTQENGTERPFSNAFHDHTAAG
LYVDIVSGEPLFSSLDKFDSGCGWPSFSRPVELNIVEKKDTSHGLVRTEVRSKHADSHLGHVFTDGPEHLTGLRYCINSA
ALRFIPADKLEEEGYGEYAHLFTTRE
>Mature_185_residues
PCLPVPFFPPRILDLPTRVLIAIEYTHHPLAPQENPMPQKYRKTPEALAALTDEQRRVTQENGTERPFSNAFHDHTAAGL
YVDIVSGEPLFSSLDKFDSGCGWPSFSRPVELNIVEKKDTSHGLVRTEVRSKHADSHLGHVFTDGPEHLTGLRYCINSAA
LRFIPADKLEEEGYGEYAHLFTTRE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=118, Percent_Identity=50, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI301336162, Length=118, Percent_Identity=50, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI73089054, Length=118, Percent_Identity=50, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI37620216, Length=118, Percent_Identity=50, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI117606353, Length=123, Percent_Identity=47.9674796747967, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI1788077, Length=127, Percent_Identity=48.8188976377953, Blast_Score=116, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17553450, Length=140, Percent_Identity=48.5714285714286, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=140, Percent_Identity=48.5714285714286, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=120, Percent_Identity=37.5, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24645799, Length=141, Percent_Identity=43.9716312056738, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=48.7394957983193, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=48.7394957983193, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=47.5, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645801, Length=152, Percent_Identity=40.7894736842105, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645804, Length=130, Percent_Identity=44.6153846153846, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221378662, Length=129, Percent_Identity=44.1860465116279, Blast_Score=104, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 20965; Mature: 20834

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCLPVPFFPPRILDLPTRVLIAIEYTHHPLAPQENPMPQKYRKTPEALAALTDEQRRVT
CCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QENGTERPFSNAFHDHTAAGLYVDIVSGEPLFSSLDKFDSGCGWPSFSRPVELNIVEKKD
HCCCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
TSHGLVRTEVRSKHADSHLGHVFTDGPEHLTGLRYCINSAALRFIPADKLEEEGYGEYAH
CCCCEEHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCEEE
LFTTRE
EEECCC
>Mature Secondary Structure 
PCLPVPFFPPRILDLPTRVLIAIEYTHHPLAPQENPMPQKYRKTPEALAALTDEQRRVT
CCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QENGTERPFSNAFHDHTAAGLYVDIVSGEPLFSSLDKFDSGCGWPSFSRPVELNIVEKKD
HCCCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
TSHGLVRTEVRSKHADSHLGHVFTDGPEHLTGLRYCINSAALRFIPADKLEEEGYGEYAH
CCCCEEHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCEEE
LFTTRE
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]