Click here to switch to the map view.

The map label for this gene is ntrX [H]

Identifier: 78355757

GI number: 78355757

Start: 727260

End: 727982

Strand: Reverse

Name: ntrX [H]

Synonym: Dde_0710

Alternate gene names: 78355757

Gene position: 727982-727260 (Counterclockwise)

Preceding gene: 78355758

Following gene: 78355752

Centisome position: 19.52

GC content: 62.52

Gene sequence:

>723_bases
GTGCGTATACTGGTAATAGACGACGAAGCCCCCACCCTGAAAATGTTTTCGCTGCTGCTCGGAGCGTACGGGCACGAGGT
GTTCACGGCAGATTCCGGAGAACGGGGACTGGCAGAGTTCCGCAGGCGGCAACCGCCGCTGGTGCTGACGGATATCCGCA
TGCCCGGCATGGACGGCATGGAAGTGCTGCGCCTCATCAAGGAACAGGCCCCCGCCACCGAAGTCATCGTCATCACGGGG
CACGGCGACATGGAGCTTGCCCTGCGGGCACTGAATCTTGATGCCACGGACTTCATCAACAAACCCATCAGACGCGAATC
ACTGGATCAGGCTCTGGCAAGGGCGCAGGAGCGCCTGAGTCTGAGAGAGGAAAACGGACACCCGCTGACACTGTCACAGG
CGCGGGGTGCTGTGGTCATTACGCTGCGCGGCACACTGGGCACGGCATCAGAAGCCGCTCTGCGTAAAGCTTTTCAGGAA
GCGGCGCAGCCCGGCAGTTGCGTTGTGCTGGATTTCGCGGCCAGCACATCCATAAACGGCGCAGCCATCAGCGTACTGGC
AGACGCCATCCGCTCCGCGTCGGGTTCCGGCGCGCCGGTCATCATCTCCGGCCTGTCCGAAAGCTTCCGCCATGTATTCG
ACGCCATGGGAGTGCTGGCACATGCCCGCACGTTTGACTGCCTGCCCGAAGCACTGGAACACGCGGCGGCTTCCGCCTGC
TGA

Upstream 100 bases:

>100_bases
CCCAAGCCGGAGGGACGCTCCGGCGGCAACAGCCTGTGGCAGACACACACTGGCGTACCGGAGGCAAAGACCGGCAGGTG
CGCAATACGGAGAAAACCGC

Downstream 100 bases:

>100_bases
TACAGGCACACCGCAGACGGCTGAATCCGGTGCTGCTGCATCAACCGCCAATGGCGGACATGCGCTTTTCCGCCACGGAA
CCGTCGGCATGCAGCTGTTC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRILVIDDEAPTLKMFSLLLGAYGHEVFTADSGERGLAEFRRRQPPLVLTDIRMPGMDGMEVLRLIKEQAPATEVIVITG
HGDMELALRALNLDATDFINKPIRRESLDQALARAQERLSLREENGHPLTLSQARGAVVITLRGTLGTASEAALRKAFQE
AAQPGSCVVLDFAASTSINGAAISVLADAIRSASGSGAPVIISGLSESFRHVFDAMGVLAHARTFDCLPEALEHAAASAC

Sequences:

>Translated_240_residues
MRILVIDDEAPTLKMFSLLLGAYGHEVFTADSGERGLAEFRRRQPPLVLTDIRMPGMDGMEVLRLIKEQAPATEVIVITG
HGDMELALRALNLDATDFINKPIRRESLDQALARAQERLSLREENGHPLTLSQARGAVVITLRGTLGTASEAALRKAFQE
AAQPGSCVVLDFAASTSINGAAISVLADAIRSASGSGAPVIISGLSESFRHVFDAMGVLAHARTFDCLPEALEHAAASAC
>Mature_240_residues
MRILVIDDEAPTLKMFSLLLGAYGHEVFTADSGERGLAEFRRRQPPLVLTDIRMPGMDGMEVLRLIKEQAPATEVIVITG
HGDMELALRALNLDATDFINKPIRRESLDQALARAQERLSLREENGHPLTLSQARGAVVITLRGTLGTASEAALRKAFQE
AAQPGSCVVLDFAASTSINGAAISVLADAIRSASGSGAPVIISGLSESFRHVFDAMGVLAHARTFDCLPEALEHAAASAC

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in the activation of nitrogen assimilatory genes such as glnA. NtrX is probably phosphorylated by ntrY and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=34.9206349206349, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=113, Percent_Identity=36.283185840708, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788905, Length=137, Percent_Identity=34.3065693430657, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 25586; Mature: 25586

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIDDEAPTLKMFSLLLGAYGHEVFTADSGERGLAEFRRRQPPLVLTDIRMPGMDGM
CEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCHH
EVLRLIKEQAPATEVIVITGHGDMELALRALNLDATDFINKPIRRESLDQALARAQERLS
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
LREENGHPLTLSQARGAVVITLRGTLGTASEAALRKAFQEAAQPGSCVVLDFAASTSING
HHCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
AAISVLADAIRSASGSGAPVIISGLSESFRHVFDAMGVLAHARTFDCLPEALEHAAASAC
HHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILVIDDEAPTLKMFSLLLGAYGHEVFTADSGERGLAEFRRRQPPLVLTDIRMPGMDGM
CEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCHH
EVLRLIKEQAPATEVIVITGHGDMELALRALNLDATDFINKPIRRESLDQALARAQERLS
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
LREENGHPLTLSQARGAVVITLRGTLGTASEAALRKAFQEAAQPGSCVVLDFAASTSING
HHCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
AAISVLADAIRSASGSGAPVIISGLSESFRHVFDAMGVLAHARTFDCLPEALEHAAASAC
HHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]