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The map label for this gene is hmcA [H]

Identifier: 78355700

GI number: 78355700

Start: 671285

End: 672952

Strand: Reverse

Name: hmcA [H]

Synonym: Dde_0653

Alternate gene names: 78355700

Gene position: 672952-671285 (Counterclockwise)

Preceding gene: 78355703

Following gene: 78355699

Centisome position: 18.04

GC content: 60.07

Gene sequence:

>1668_bases
ATGCGTTTCACCATTTTTCAAAGGACTGCCACTATGTTGAAAAAAAAATCACTGCTGCAATGGGCAGGGATTCTGGCTGC
CGTTGCCGTCATATCGGCATCGGGGTTCCTGGTCCGGAGCACCAGCGCCATGCCCGAACCCGCGGGCGCGGGCGGCGGCA
ATGCCGACCTTATCCGGATCGACGTTGTTAAACAGTTCGACGATCTGGAGCTGCCGCCGGCTTCTTTCCGCCACGACAAG
CACACTGCCGCGCTGAAAGACAAAGATTGTTCCGCCTGCCACAAAACCGTGGACGGCAAAATGTCGCTCAAGTTTCAGCG
CACCGCGGATGAAAGCGCCGAACAACTGAAAAAAGTCTACCATGACAACTGTATCGGCTGCCATACCGAGATGGTGGACA
ACGGTCAGAAGTCCGGTCCGCTGGACAGTGAATGCCGCAGCTGCCACGTGGCGCAGGAAGCACCGGCAGACCGCGCCGAA
GCCGGCATGGACAAATCGCTGCACTACCGCCACATTGCCGCGGCAAGCATCAAGCCCGCCGGCGGTGCAGATGTCAACTG
CGGCACCTGCCACCATGTTTACGACAAAGCAGCTGAAAAGACCGTGTGGAAAAAAGGCGAGGAAGACAGCTGCCGCGCCT
GCCACAAGGACGCACCCGTCACGGCTGACGGCGTGACTGTTTCTGCTTTTGCCGATGCAGCCCACAACCAGTGCGTGGTG
TGCCACGTGACCACGGCACAGGCACAGCAGAAGACCGGCCCCGTCAACTGCGCAGGGTGCCACACCACACAGGCGCAGGC
CGCGTACGAAGTGGTGAAGGATGTGCCCCGCCTTGACCGCGGACAGCCCGACGCCGTCGTCATGACTCCCCCTGCCGGTT
CAAAGACCGTCAAAAAAGAAGCCGGTCCCGGTTCCATCGCCGCCGTGGCCTTCAACCACAAGGTGCACGAACAGGCCAAT
GACACCTGCCGCGTCTGCCATCACGAAAAAATCGCCAGCTGCTCCGAATGCCATACGACCGAAGGCAAGAAGGAAGGCGG
CTTTGTTCAGCTTTCGCAGGCCATGCATGCCAAGCAGGCCGATGCCAGCTGCGTAGGCTGCCATAACAAGCAGAAAGAGC
AGCCCGTATGCGCCGGCTGCCACAGCTTTGTCCCCTACAAAAACACGGAAGATTCATGCGCCAAATGCCACAATGTTCCC
GCTGAGCTCGCTCCGCAGGGCGCTGAGGCACTGAGCAAGGAAGAGCGCGTCTCCGTAGGCATGCTGGTGGCTTCTTCGCG
CCAGTACACCAAGGGCACTTACGACCTTAACGACGTCCCCGACCGCGTTACCATTGATGCGATGGTGAACGAGTACGAGG
CTGTGGACTTCCCGCACCGCAAGATCATCAAGACCATGCTGGCGGGAATTGAAGGCGACAGACTTGCCGCCGCGTTCCAC
AACGAGCCCGGCACGTTCTGCCAGGGCTGCCACCACAACAGCCCCGTTTCAAAGACACCCCCCGCATGCGCCACATGCCA
CGGCAAGCCGTTTGAGCTGGATCAGGGCGACCGCCCGGGCCTGAAGGCCGCCTACCACCAGCAGTGCATGGGATGCCACA
CCGCCATGCGCATTGAAAAGCCTGCCAACACGGCTTGCAACGAGTGTCACAAAAAACGCGATCTGTAG

Upstream 100 bases:

>100_bases
ATGGGTGTGTCGTTTTTTGCGCCCTTTTTGCGTTCTGCCCGCAGGCTTACCGCCACCGGTCACGGGGATCTGTCCGGCCG
TCGGTACAGGATGTCTGAGG

Downstream 100 bases:

>100_bases
GATATTAGCAAGGAGACTAGTCCATGCGTCGAAGAACCTTTCTGAGCCTGCTCGGTGCTGCCGGACTTTCGGTGGCAGCG
GGCAAGCCCGCCGCCGCGGG

Product: high-molecular-weight cytochrome c

Products: NA

Alternate protein names: Cytochrome CC3 [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MRFTIFQRTATMLKKKSLLQWAGILAAVAVISASGFLVRSTSAMPEPAGAGGGNADLIRIDVVKQFDDLELPPASFRHDK
HTAALKDKDCSACHKTVDGKMSLKFQRTADESAEQLKKVYHDNCIGCHTEMVDNGQKSGPLDSECRSCHVAQEAPADRAE
AGMDKSLHYRHIAAASIKPAGGADVNCGTCHHVYDKAAEKTVWKKGEEDSCRACHKDAPVTADGVTVSAFADAAHNQCVV
CHVTTAQAQQKTGPVNCAGCHTTQAQAAYEVVKDVPRLDRGQPDAVVMTPPAGSKTVKKEAGPGSIAAVAFNHKVHEQAN
DTCRVCHHEKIASCSECHTTEGKKEGGFVQLSQAMHAKQADASCVGCHNKQKEQPVCAGCHSFVPYKNTEDSCAKCHNVP
AELAPQGAEALSKEERVSVGMLVASSRQYTKGTYDLNDVPDRVTIDAMVNEYEAVDFPHRKIIKTMLAGIEGDRLAAAFH
NEPGTFCQGCHHNSPVSKTPPACATCHGKPFELDQGDRPGLKAAYHQQCMGCHTAMRIEKPANTACNECHKKRDL

Sequences:

>Translated_555_residues
MRFTIFQRTATMLKKKSLLQWAGILAAVAVISASGFLVRSTSAMPEPAGAGGGNADLIRIDVVKQFDDLELPPASFRHDK
HTAALKDKDCSACHKTVDGKMSLKFQRTADESAEQLKKVYHDNCIGCHTEMVDNGQKSGPLDSECRSCHVAQEAPADRAE
AGMDKSLHYRHIAAASIKPAGGADVNCGTCHHVYDKAAEKTVWKKGEEDSCRACHKDAPVTADGVTVSAFADAAHNQCVV
CHVTTAQAQQKTGPVNCAGCHTTQAQAAYEVVKDVPRLDRGQPDAVVMTPPAGSKTVKKEAGPGSIAAVAFNHKVHEQAN
DTCRVCHHEKIASCSECHTTEGKKEGGFVQLSQAMHAKQADASCVGCHNKQKEQPVCAGCHSFVPYKNTEDSCAKCHNVP
AELAPQGAEALSKEERVSVGMLVASSRQYTKGTYDLNDVPDRVTIDAMVNEYEAVDFPHRKIIKTMLAGIEGDRLAAAFH
NEPGTFCQGCHHNSPVSKTPPACATCHGKPFELDQGDRPGLKAAYHQQCMGCHTAMRIEKPANTACNECHKKRDL
>Mature_555_residues
MRFTIFQRTATMLKKKSLLQWAGILAAVAVISASGFLVRSTSAMPEPAGAGGGNADLIRIDVVKQFDDLELPPASFRHDK
HTAALKDKDCSACHKTVDGKMSLKFQRTADESAEQLKKVYHDNCIGCHTEMVDNGQKSGPLDSECRSCHVAQEAPADRAE
AGMDKSLHYRHIAAASIKPAGGADVNCGTCHHVYDKAAEKTVWKKGEEDSCRACHKDAPVTADGVTVSAFADAAHNQCVV
CHVTTAQAQQKTGPVNCAGCHTTQAQAAYEVVKDVPRLDRGQPDAVVMTPPAGSKTVKKEAGPGSIAAVAFNHKVHEQAN
DTCRVCHHEKIASCSECHTTEGKKEGGFVQLSQAMHAKQADASCVGCHNKQKEQPVCAGCHSFVPYKNTEDSCAKCHNVP
AELAPQGAEALSKEERVSVGMLVASSRQYTKGTYDLNDVPDRVTIDAMVNEYEAVDFPHRKIIKTMLAGIEGDRLAAAFH
NEPGTFCQGCHHNSPVSKTPPACATCHGKPFELDQGDRPGLKAAYHQQCMGCHTAMRIEKPANTACNECHKKRDL

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002322
- InterPro:   IPR020942
- InterPro:   IPR011346
- InterPro:   IPR011031 [H]

Pfam domain/function: PF02085 Cytochrom_CIII [H]

EC number: NA

Molecular weight: Translated: 59703; Mature: 59703

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTIFQRTATMLKKKSLLQWAGILAAVAVISASGFLVRSTSAMPEPAGAGGGNADLIRI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEE
DVVKQFDDLELPPASFRHDKHTAALKDKDCSACHKTVDGKMSLKFQRTADESAEQLKKVY
EEECCCCCCCCCCHHCCCCCHHHHCCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHH
HDNCIGCHTEMVDNGQKSGPLDSECRSCHVAQEAPADRAEAGMDKSLHYRHIAAASIKPA
CCCCCCCHHHHHCCCCCCCCCCHHHHHCCCHHHCCCCHHHHCCCCCCHHHHHHHCCCCCC
GGADVNCGTCHHVYDKAAEKTVWKKGEEDSCRACHKDAPVTADGVTVSAFADAAHNQCVV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEHHHHCCCCCEEE
CHVTTAQAQQKTGPVNCAGCHTTQAQAAYEVVKDVPRLDRGQPDAVVMTPPAGSKTVKKE
EEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHCC
AGPGSIAAVAFNHKVHEQANDTCRVCHHEKIASCSECHTTEGKKEGGFVQLSQAMHAKQA
CCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCHHHHHCCCCCCCCCEEEHHHHHHHHHC
DASCVGCHNKQKEQPVCAGCHSFVPYKNTEDSCAKCHNVPAELAPQGAEALSKEERVSVG
CCHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCHHHCCCCHHHHCHHHHHEEE
MLVASSRQYTKGTYDLNDVPDRVTIDAMVNEYEAVDFPHRKIIKTMLAGIEGDRLAAAFH
EEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEC
NEPGTFCQGCHHNSPVSKTPPACATCHGKPFELDQGDRPGLKAAYHQQCMGCHTAMRIEK
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
PANTACNECHKKRDL
CCCHHHHHHHHHCCC
>Mature Secondary Structure
MRFTIFQRTATMLKKKSLLQWAGILAAVAVISASGFLVRSTSAMPEPAGAGGGNADLIRI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEE
DVVKQFDDLELPPASFRHDKHTAALKDKDCSACHKTVDGKMSLKFQRTADESAEQLKKVY
EEECCCCCCCCCCHHCCCCCHHHHCCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHH
HDNCIGCHTEMVDNGQKSGPLDSECRSCHVAQEAPADRAEAGMDKSLHYRHIAAASIKPA
CCCCCCCHHHHHCCCCCCCCCCHHHHHCCCHHHCCCCHHHHCCCCCCHHHHHHHCCCCCC
GGADVNCGTCHHVYDKAAEKTVWKKGEEDSCRACHKDAPVTADGVTVSAFADAAHNQCVV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEHHHHCCCCCEEE
CHVTTAQAQQKTGPVNCAGCHTTQAQAAYEVVKDVPRLDRGQPDAVVMTPPAGSKTVKKE
EEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHCC
AGPGSIAAVAFNHKVHEQANDTCRVCHHEKIASCSECHTTEGKKEGGFVQLSQAMHAKQA
CCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCHHHHHCCCCCCCCCEEEHHHHHHHHHC
DASCVGCHNKQKEQPVCAGCHSFVPYKNTEDSCAKCHNVPAELAPQGAEALSKEERVSVG
CCHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCHHHCCCCHHHHCHHHHHEEE
MLVASSRQYTKGTYDLNDVPDRVTIDAMVNEYEAVDFPHRKIIKTMLAGIEGDRLAAAFH
EEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEC
NEPGTFCQGCHHNSPVSKTPPACATCHGKPFELDQGDRPGLKAAYHQQCMGCHTAMRIEK
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
PANTACNECHKKRDL
CCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1846136; 2163671; 1313289; 8335628; 7925451; 12356749 [H]