Click here to switch to the map view.

The map label for this gene is rlmM [H]

Identifier: 78355354

GI number: 78355354

Start: 295788

End: 296714

Strand: Reverse

Name: rlmM [H]

Synonym: Dde_0307

Alternate gene names: 78355354

Gene position: 296714-295788 (Counterclockwise)

Preceding gene: 78355358

Following gene: 78355353

Centisome position: 7.95

GC content: 62.78

Gene sequence:

>927_bases
ATGACACGCCGGACAGTGTATCTGGCCGCAAAAGGCTACACGGAAGACCTGCTGCAGGAACTCGGCCATGCCGGAGTACA
TGTAACAGAGGTCCGCGACAGGCTGGTTCTTGCGCAGGGGGCCGCTGTTCATGCTGCATGGGCACAGAACATCTGGCTCG
AACCGGAGTTCATCACCATCAGTTCCATAAAGGACGGTGCGCGGCAGCTCCGGCAAAGGCAGCGTAACTGGGCGCTGTGT
GCGGCCGGCGGCAACCATGGCAGGGCAAAGCTCATCCAGTCGTCTCTGCCGCATGTCTCGGCAAAGCCGGTGGTCTTCGG
CAGTGAGGCACCCCGGGCGCCGCTGGGGTCGTGGACTCTGTGGGAACCGGACACCATACTTGCATCCGCAGCCTGCACCA
GCGCCTTTGCCGACGGCGAGGTACTTTTTGAAGAAGACAGGCAGACTCCGCCCACCCGCGCTTATCTCAAGCTGTGGGAA
GCTTTCACCATAACGGGATGCAGACCGCGGGAAGACGAGCTGTGCCTCGATCTGGGCAGCAGCCCCGGCGGCTGGAGCTG
GGTGCTGGCACAATGCGGGGCCCGCGTGTTCAGTGTGGACAAGGCGGCACTTGCCCCGCACATTGCCGCGCATCCGCACA
TCGACTTCTGCTCCGGCAGTGCGTTCGGGCTGGACCCGCGCCACGCAGGCGAGGTGGACTGGCTGTGCTGCGACGTCATC
TGCTACCCCGACAGACTGCTGGCCATGGTGGCGCGCTGGCTTGAGCTGGGTTCGGTACGCAACTTTGTCTGCACGCTGAA
GTTTCAGGGCGAGACAGACCACGAAACGGCGCGGCAGTTCGCCGCCATTCCCGGTTCGCGTCTTGTGCATCTTTCGTGCA
ACAAACACGAGCTCACATGGATGCGGCTTGACCCGCGGCAGATATAA

Upstream 100 bases:

>100_bases
ACACACCGGCACCGCACAACAGCGCCGCAGCCGGGCGCACTTGCCATAACAGGCTGCCTGCGCTACCACCCGCGCGGCAA
CAGCAACAATCGGAGGAAAA

Downstream 100 bases:

>100_bases
CCCCGCCGGACACCGCGGGGCACCGCGGGGCATCCGTCCGTCCGCCCGCCCCTTGCGGTGCCGTGTCAATTGATGCATGT
TCAATACAGCAAAAACCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTRRTVYLAAKGYTEDLLQELGHAGVHVTEVRDRLVLAQGAAVHAAWAQNIWLEPEFITISSIKDGARQLRQRQRNWALC
AAGGNHGRAKLIQSSLPHVSAKPVVFGSEAPRAPLGSWTLWEPDTILASAACTSAFADGEVLFEEDRQTPPTRAYLKLWE
AFTITGCRPREDELCLDLGSSPGGWSWVLAQCGARVFSVDKAALAPHIAAHPHIDFCSGSAFGLDPRHAGEVDWLCCDVI
CYPDRLLAMVARWLELGSVRNFVCTLKFQGETDHETARQFAAIPGSRLVHLSCNKHELTWMRLDPRQI

Sequences:

>Translated_308_residues
MTRRTVYLAAKGYTEDLLQELGHAGVHVTEVRDRLVLAQGAAVHAAWAQNIWLEPEFITISSIKDGARQLRQRQRNWALC
AAGGNHGRAKLIQSSLPHVSAKPVVFGSEAPRAPLGSWTLWEPDTILASAACTSAFADGEVLFEEDRQTPPTRAYLKLWE
AFTITGCRPREDELCLDLGSSPGGWSWVLAQCGARVFSVDKAALAPHIAAHPHIDFCSGSAFGLDPRHAGEVDWLCCDVI
CYPDRLLAMVARWLELGSVRNFVCTLKFQGETDHETARQFAAIPGSRLVHLSCNKHELTWMRLDPRQI
>Mature_307_residues
TRRTVYLAAKGYTEDLLQELGHAGVHVTEVRDRLVLAQGAAVHAAWAQNIWLEPEFITISSIKDGARQLRQRQRNWALCA
AGGNHGRAKLIQSSLPHVSAKPVVFGSEAPRAPLGSWTLWEPDTILASAACTSAFADGEVLFEEDRQTPPTRAYLKLWEA
FTITGCRPREDELCLDLGSSPGGWSWVLAQCGARVFSVDKAALAPHIAAHPHIDFCSGSAFGLDPRHAGEVDWLCCDVIC
YPDRLLAMVARWLELGSVRNFVCTLKFQGETDHETARQFAAIPGSRLVHLSCNKHELTWMRLDPRQI

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=131, Percent_Identity=29.0076335877863, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 34074; Mature: 33943

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRTVYLAAKGYTEDLLQELGHAGVHVTEVRDRLVLAQGAAVHAAWAQNIWLEPEFITI
CCCEEEEEEECCCHHHHHHHHCCCCEEEEHHHHHHEEECCCEEEEHHHHCCCCCCCEEEE
SSIKDGARQLRQRQRNWALCAAGGNHGRAKLIQSSLPHVSAKPVVFGSEAPRAPLGSWTL
CCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEE
WEPDTILASAACTSAFADGEVLFEEDRQTPPTRAYLKLWEAFTITGCRPREDELCLDLGS
ECCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCCEEECCC
SPGGWSWVLAQCGARVFSVDKAALAPHIAAHPHIDFCSGSAFGLDPRHAGEVDWLCCDVI
CCCCHHHHHHHCCCCEEECCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEEEEE
CYPDRLLAMVARWLELGSVRNFVCTLKFQGETDHETARQFAAIPGSRLVHLSCNKHELTW
ECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEE
MRLDPRQI
EECCCCCC
>Mature Secondary Structure 
TRRTVYLAAKGYTEDLLQELGHAGVHVTEVRDRLVLAQGAAVHAAWAQNIWLEPEFITI
CCEEEEEEECCCHHHHHHHHCCCCEEEEHHHHHHEEECCCEEEEHHHHCCCCCCCEEEE
SSIKDGARQLRQRQRNWALCAAGGNHGRAKLIQSSLPHVSAKPVVFGSEAPRAPLGSWTL
CCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEE
WEPDTILASAACTSAFADGEVLFEEDRQTPPTRAYLKLWEAFTITGCRPREDELCLDLGS
ECCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCCEEECCC
SPGGWSWVLAQCGARVFSVDKAALAPHIAAHPHIDFCSGSAFGLDPRHAGEVDWLCCDVI
CCCCHHHHHHHCCCCEEECCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEEEEE
CYPDRLLAMVARWLELGSVRNFVCTLKFQGETDHETARQFAAIPGSRLVHLSCNKHELTW
ECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEE
MRLDPRQI
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA