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The map label for this gene is kamA [H]

Identifier: 78355236

GI number: 78355236

Start: 174319

End: 175683

Strand: Reverse

Name: kamA [H]

Synonym: Dde_0189

Alternate gene names: 78355236

Gene position: 175683-174319 (Counterclockwise)

Preceding gene: 78355237

Following gene: 78355235

Centisome position: 4.71

GC content: 58.17

Gene sequence:

>1365_bases
ATGAAAGAGCTCAACGAACGTCAACGCGAAGTAGTAAGCATGCTGGGCAACAGCACTTCCACCTCCGGCTGGGAGGACTG
GAAATGGCATGTCCGCAATTCCATCCGTACTGTCGAAGCAGCGGAAAAAATTCTCGGAGTCACCTTCAGCGATGAAAAAC
GCGCTCTGTACAAGCGCACGCTGGACAAATTCCCCATGTCCATCACCCCCTATTATTTTTCGCTCATCGATCAGGAAGAC
TACGAAAGCGATCCCGTTTTCATGCAGGCTTTTCCGGATATACGCGAACTGAACGTAAGCCCGCACGACATGGCAGACCC
GCTGCACGAAGATGAAGACAGCCCCGCACCGGGCATTACACACCGTTACCCCGACCGCGTGTTGTTTCACGTTTCCAACC
TGTGCTCCATGTACTGCCGCCACTGCACCAGAAAGCGCAAGGTTGGCGACAGGGACTCGGTGCCGGACCGCGGACAGCTG
AAACAGGGCATTGAATACATCCGCCGCACCCCCGCCATACGCGACGTGCTGCTTTCCGGCGGCGACCCGCTGATGCTCTC
TGACGAACGGCTGGACTGGCTGCTGGGTGAAATACGCAGCATCCCGCATGTGGAAATTATCCGCATCGGCAGCCGCATGC
CCGTGGTCCTGCCCTACCGCATCACCGACGGGCTGCTTGCCGTACTTAAAAAACACCACCCGCTGTGGCTGAACACACAT
TTCAACCACCCGAGAGAGCTTACCCGCACATCACGCCGGGCACTGGCCCGCATGGCGGATGCAGGCATTCCGCTGGGCAA
CCAGAGTGTTCTGCTGGCGGATGTGAACGACTGCCCCCGCCTTTTCAGAACTCTGAACCAGAAGCTGGTGCAGAACAGAG
TGCGCCCTTACTACATGTATCAGTGCGACCTGTCCGAAGGGCTTTCCCACTTCCGCACGCCGGTGGGCAAGGGTATCGAA
ATTATTGAAAGCCTTGTGGGACATACCAGCGGCATGGCTGTTCCGACCTATGTCATAGACGCCCCCGGCGGTGGCGGCAA
AATACCCATGATGCCCAACTACGCCATATCTCAGGGCGTAAACAAAGTGGTGCTGCGCAATTACGAAGGCGTCATAACAA
CATACACCGAGCCGGACAGCTATGAGCCATCCTATTGCGACCGCGACTGCCGGTCGTGCCATCTGACGCTGAAAGAAGAC
GACGCGGACGAAACCGGCGCCATAGGTATAGAAAAGCTGCTCTCGGACTGGGACGACACAACCAGCCTTACACCGGAAAA
CAACGAGCGCCTGGCCCGCCGCGATGCCCCTGCGGACAACCCCGCGGACGACGGCGCTGCGCCTGCGGTGCAGGCAAAGG
GGTGA

Upstream 100 bases:

>100_bases
ACATGCCGCACTCGGAAAGCGCCGCAGCGCTGCCCGCAGGCAGCCCCGCCGACACGCGGCCAGACGCAACAAGACGGCCC
TTGTTGCCGCGCCACCATCC

Downstream 100 bases:

>100_bases
CAGCATGCAGACAAGCCTGACCGAATTTGTCACCGAGACACGCCCCGTGTGTCCTCCCGATGCGGAACAGCCCGACGAAG
TGCGCACCGTCGGCCGTTCC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKELNERQREVVSMLGNSTSTSGWEDWKWHVRNSIRTVEAAEKILGVTFSDEKRALYKRTLDKFPMSITPYYFSLIDQED
YESDPVFMQAFPDIRELNVSPHDMADPLHEDEDSPAPGITHRYPDRVLFHVSNLCSMYCRHCTRKRKVGDRDSVPDRGQL
KQGIEYIRRTPAIRDVLLSGGDPLMLSDERLDWLLGEIRSIPHVEIIRIGSRMPVVLPYRITDGLLAVLKKHHPLWLNTH
FNHPRELTRTSRRALARMADAGIPLGNQSVLLADVNDCPRLFRTLNQKLVQNRVRPYYMYQCDLSEGLSHFRTPVGKGIE
IIESLVGHTSGMAVPTYVIDAPGGGGKIPMMPNYAISQGVNKVVLRNYEGVITTYTEPDSYEPSYCDRDCRSCHLTLKED
DADETGAIGIEKLLSDWDDTTSLTPENNERLARRDAPADNPADDGAAPAVQAKG

Sequences:

>Translated_454_residues
MKELNERQREVVSMLGNSTSTSGWEDWKWHVRNSIRTVEAAEKILGVTFSDEKRALYKRTLDKFPMSITPYYFSLIDQED
YESDPVFMQAFPDIRELNVSPHDMADPLHEDEDSPAPGITHRYPDRVLFHVSNLCSMYCRHCTRKRKVGDRDSVPDRGQL
KQGIEYIRRTPAIRDVLLSGGDPLMLSDERLDWLLGEIRSIPHVEIIRIGSRMPVVLPYRITDGLLAVLKKHHPLWLNTH
FNHPRELTRTSRRALARMADAGIPLGNQSVLLADVNDCPRLFRTLNQKLVQNRVRPYYMYQCDLSEGLSHFRTPVGKGIE
IIESLVGHTSGMAVPTYVIDAPGGGGKIPMMPNYAISQGVNKVVLRNYEGVITTYTEPDSYEPSYCDRDCRSCHLTLKED
DADETGAIGIEKLLSDWDDTTSLTPENNERLARRDAPADNPADDGAAPAVQAKG
>Mature_454_residues
MKELNERQREVVSMLGNSTSTSGWEDWKWHVRNSIRTVEAAEKILGVTFSDEKRALYKRTLDKFPMSITPYYFSLIDQED
YESDPVFMQAFPDIRELNVSPHDMADPLHEDEDSPAPGITHRYPDRVLFHVSNLCSMYCRHCTRKRKVGDRDSVPDRGQL
KQGIEYIRRTPAIRDVLLSGGDPLMLSDERLDWLLGEIRSIPHVEIIRIGSRMPVVLPYRITDGLLAVLKKHHPLWLNTH
FNHPRELTRTSRRALARMADAGIPLGNQSVLLADVNDCPRLFRTLNQKLVQNRVRPYYMYQCDLSEGLSHFRTPVGKGIE
IIESLVGHTSGMAVPTYVIDAPGGGGKIPMMPNYAISQGVNKVVLRNYEGVITTYTEPDSYEPSYCDRDCRSCHLTLKED
DADETGAIGIEKLLSDWDDTTSLTPENNERLARRDAPADNPADDGAAPAVQAKG

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=334, Percent_Identity=31.1377245508982, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 51375; Mature: 51375

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELNERQREVVSMLGNSTSTSGWEDWKWHVRNSIRTVEAAEKILGVTFSDEKRALYKRT
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LDKFPMSITPYYFSLIDQEDYESDPVFMQAFPDIRELNVSPHDMADPLHEDEDSPAPGIT
HHHCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCHHHCCCCCCCCCCCCCCCC
HRYPDRVLFHVSNLCSMYCRHCTRKRKVGDRDSVPDRGQLKQGIEYIRRTPAIRDVLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCC
GDPLMLSDERLDWLLGEIRSIPHVEIIRIGSRMPVVLPYRITDGLLAVLKKHHPLWLNTH
CCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCEEEECC
FNHPRELTRTSRRALARMADAGIPLGNQSVLLADVNDCPRLFRTLNQKLVQNRVRPYYMY
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEE
QCDLSEGLSHFRTPVGKGIEIIESLVGHTSGMAVPTYVIDAPGGGGKIPMMPNYAISQGV
ECCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
NKVVLRNYEGVITTYTEPDSYEPSYCDRDCRSCHLTLKEDDADETGAIGIEKLLSDWDDT
HHHHHCCCCCEEEECCCCCCCCCCHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCCC
TSLTPENNERLARRDAPADNPADDGAAPAVQAKG
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKELNERQREVVSMLGNSTSTSGWEDWKWHVRNSIRTVEAAEKILGVTFSDEKRALYKRT
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LDKFPMSITPYYFSLIDQEDYESDPVFMQAFPDIRELNVSPHDMADPLHEDEDSPAPGIT
HHHCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCHHHCCCCCCCCCCCCCCCC
HRYPDRVLFHVSNLCSMYCRHCTRKRKVGDRDSVPDRGQLKQGIEYIRRTPAIRDVLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCC
GDPLMLSDERLDWLLGEIRSIPHVEIIRIGSRMPVVLPYRITDGLLAVLKKHHPLWLNTH
CCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCEEEECC
FNHPRELTRTSRRALARMADAGIPLGNQSVLLADVNDCPRLFRTLNQKLVQNRVRPYYMY
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEE
QCDLSEGLSHFRTPVGKGIEIIESLVGHTSGMAVPTYVIDAPGGGGKIPMMPNYAISQGV
ECCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
NKVVLRNYEGVITTYTEPDSYEPSYCDRDCRSCHLTLKEDDADETGAIGIEKLLSDWDDT
HHHHHCCCCCEEEECCCCCCCCCCHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCCC
TSLTPENNERLARRDAPADNPADDGAAPAVQAKG
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]