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The map label for this gene is glcD [H]

Identifier: 78355229

GI number: 78355229

Start: 167691

End: 169085

Strand: Reverse

Name: glcD [H]

Synonym: Dde_0182

Alternate gene names: 78355229

Gene position: 169085-167691 (Counterclockwise)

Preceding gene: 78355230

Following gene: 78355228

Centisome position: 4.53

GC content: 62.22

Gene sequence:

>1395_bases
ATGACCTGCACCACCACACCTGACCTTGACCGCATTGCTGAAGAGCTTACAGCCATTCTGGGGCCGCAGGGCGTACTGAC
CGCCCCCGGAGAACCCTATGACCGCGATTCTTCGCCTTTCACAGCCGCACCGGACATCGTGGCACTGCCCGAAACGACCG
AACAGGTCAGCCGCATAGTCCGGCTTGCCAGCCGGCTCGGTTTTGCCCTCATTCCCCGCGGGGCGGGCACCGGCACCGCC
GGCGGCTGCCTGCCGCTGAGCGGCGGAGTTGTGATATCGCTGGAACGCATGAAGCGCATCATCACGCTGGATACCCGAAG
CCTGTACGCACATGTGGAAGCCGGAGTGATTACCGGAGAGCTGCGCGATGCCGCAGCCGGACAGGGACTGTTTTTTCCGC
CTGATCCGGCAAGTCTGGACACCTCGACCATAGGCGGCAACGTGGCCACCAATGCCGGCGGCCCCGCCTGCGTCAAATAC
GGTGTCATGCGCGACTATGTGCTGGGTGTCGAAGCCGTCATGCCCGACGGCGAAGTGATACAGGCGGGAGTACGCACGCG
CAAAGGCGTTGTGGGCTACGACATGGCGCATCTGCTTACAGGGTCGGAAGGCACGCTGGGTATCATCACCTCCGTGTATC
TGAAGCTCATCCCGCTGCCTCCCGCCACGGTGGGGCTGGCAGCCGTGTTCCCTTCGCTGCCCGATGCCATGCGCACAGTG
GCCGCCGTGCTGGGACGCGGGCACCTGCCCAGCGCCATTGAATTTCTGGACCATAAATGTCTGGGGCTTGTGGGTGACAA
GCTGCCCTTTTCCGTGGAAGACAAATCCGCCTCGCTGCTGATCATCGAACTGGACGGACGGACGGAAGCCATCACACCGG
AAATCGACATGGTGGCGGCCATATGTACCGAGCACGGCGCCACGCACCTGATGCCCGGCGGCACAAGGAAGGAACGCGAC
ACCATCTGGAACGTACGCCGCGAAGTTTCCACACGCATACGCGAACATGCGGCACGGTCCTTCTCGGAAGATGTGGTAGT
GCCCATCGGCAGCATAGCCTCATTCATTGCCGAGGTTCCCGACTTTGAAAACCGGTTCGGGCTGGATATATTCGCCTTCG
GCCATGCGGGCGACGGAAACATCCACCTTATTCTCACCGTGCCCCGCGCGGCACGGCCGGACACGCAGGCACCGCGTCTT
GAAGACGGCATAGAAGCCGTTGCCCGCCGCGTACTTGAACTGGGCGGCACCATTTCCGGCGAACACGGTGTGGGCGAAGC
CAAAAAACACCTGCTGCCGCTGGAAATAGCACCGGCGTCACTGCGGCTGCAGCGCGGCATCAAACAGCTGTTCGACCCCT
GCAACATCATGAATCCGGGCAAGGTCTTTCCCTAG

Upstream 100 bases:

>100_bases
GAAAGGCGTGAGCGGCTTTTTTTACGCACAGGGCCAACCCGTCTGCGGCAACAGCCCGGACGGCGGCCATATATCCGGCT
GCCCGCACGGAGAAACGCAA

Downstream 100 bases:

>100_bases
CCTGTATATTTTCCGGAGCTGAACGTGGCAAAACACAGAAGACGAAAACCAATGCCCCCGCTGCCACCCCCGCGGTTTTC
CCGCCGGCTGTATGTGCATG

Product: D-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTCTTTPDLDRIAEELTAILGPQGVLTAPGEPYDRDSSPFTAAPDIVALPETTEQVSRIVRLASRLGFALIPRGAGTGTA
GGCLPLSGGVVISLERMKRIITLDTRSLYAHVEAGVITGELRDAAAGQGLFFPPDPASLDTSTIGGNVATNAGGPACVKY
GVMRDYVLGVEAVMPDGEVIQAGVRTRKGVVGYDMAHLLTGSEGTLGIITSVYLKLIPLPPATVGLAAVFPSLPDAMRTV
AAVLGRGHLPSAIEFLDHKCLGLVGDKLPFSVEDKSASLLIIELDGRTEAITPEIDMVAAICTEHGATHLMPGGTRKERD
TIWNVRREVSTRIREHAARSFSEDVVVPIGSIASFIAEVPDFENRFGLDIFAFGHAGDGNIHLILTVPRAARPDTQAPRL
EDGIEAVARRVLELGGTISGEHGVGEAKKHLLPLEIAPASLRLQRGIKQLFDPCNIMNPGKVFP

Sequences:

>Translated_464_residues
MTCTTTPDLDRIAEELTAILGPQGVLTAPGEPYDRDSSPFTAAPDIVALPETTEQVSRIVRLASRLGFALIPRGAGTGTA
GGCLPLSGGVVISLERMKRIITLDTRSLYAHVEAGVITGELRDAAAGQGLFFPPDPASLDTSTIGGNVATNAGGPACVKY
GVMRDYVLGVEAVMPDGEVIQAGVRTRKGVVGYDMAHLLTGSEGTLGIITSVYLKLIPLPPATVGLAAVFPSLPDAMRTV
AAVLGRGHLPSAIEFLDHKCLGLVGDKLPFSVEDKSASLLIIELDGRTEAITPEIDMVAAICTEHGATHLMPGGTRKERD
TIWNVRREVSTRIREHAARSFSEDVVVPIGSIASFIAEVPDFENRFGLDIFAFGHAGDGNIHLILTVPRAARPDTQAPRL
EDGIEAVARRVLELGGTISGEHGVGEAKKHLLPLEIAPASLRLQRGIKQLFDPCNIMNPGKVFP
>Mature_463_residues
TCTTTPDLDRIAEELTAILGPQGVLTAPGEPYDRDSSPFTAAPDIVALPETTEQVSRIVRLASRLGFALIPRGAGTGTAG
GCLPLSGGVVISLERMKRIITLDTRSLYAHVEAGVITGELRDAAAGQGLFFPPDPASLDTSTIGGNVATNAGGPACVKYG
VMRDYVLGVEAVMPDGEVIQAGVRTRKGVVGYDMAHLLTGSEGTLGIITSVYLKLIPLPPATVGLAAVFPSLPDAMRTVA
AVLGRGHLPSAIEFLDHKCLGLVGDKLPFSVEDKSASLLIIELDGRTEAITPEIDMVAAICTEHGATHLMPGGTRKERDT
IWNVRREVSTRIREHAARSFSEDVVVPIGSIASFIAEVPDFENRFGLDIFAFGHAGDGNIHLILTVPRAARPDTQAPRLE
DGIEAVARRVLELGGTISGEHGVGEAKKHLLPLEIAPASLRLQRGIKQLFDPCNIMNPGKVFP

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=465, Percent_Identity=35.4838709677419, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI37595754, Length=490, Percent_Identity=33.6734693877551, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI119964728, Length=434, Percent_Identity=31.3364055299539, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI4501993, Length=224, Percent_Identity=33.4821428571429, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789351, Length=434, Percent_Identity=31.3364055299539, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787977, Length=519, Percent_Identity=27.9383429672447, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI48994907, Length=259, Percent_Identity=27.4131274131274, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994914, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71992373, Length=460, Percent_Identity=33.695652173913, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71992381, Length=460, Percent_Identity=32.3913043478261, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71992392, Length=384, Percent_Identity=33.3333333333333, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17534361, Length=442, Percent_Identity=27.1493212669683, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17556096, Length=464, Percent_Identity=23.7068965517241, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320027, Length=479, Percent_Identity=28.39248434238, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6320764, Length=471, Percent_Identity=28.4501061571125, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6320023, Length=478, Percent_Identity=28.2426778242678, Blast_Score=175, Evalue=1e-44,
Organism=Drosophila melanogaster, GI18921117, Length=465, Percent_Identity=29.6774193548387, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24639277, Length=465, Percent_Identity=29.6774193548387, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24639275, Length=465, Percent_Identity=29.6774193548387, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653753, Length=231, Percent_Identity=30.7359307359307, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49041; Mature: 48910

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCTTTPDLDRIAEELTAILGPQGVLTAPGEPYDRDSSPFTAAPDIVALPETTEQVSRIV
CCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
RLASRLGFALIPRGAGTGTAGGCLPLSGGVVISLERMKRIITLDTRSLYAHVEAGVITGE
HHHHHCCEEEEECCCCCCCCCCCEEECCCEEEEHHHHHHHHEECCHHHHHHHHCCEEECC
LRDAAAGQGLFFPPDPASLDTSTIGGNVATNAGGPACVKYGVMRDYVLGVEAVMPDGEVI
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
QAGVRTRKGVVGYDMAHLLTGSEGTLGIITSVYLKLIPLPPATVGLAAVFPSLPDAMRTV
HHHHHHCCCCCCCCHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHH
AAVLGRGHLPSAIEFLDHKCLGLVGDKLPFSVEDKSASLLIIELDGRTEAITPEIDMVAA
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCCHHHHHHH
ICTEHGATHLMPGGTRKERDTIWNVRREVSTRIREHAARSFSEDVVVPIGSIASFIAEVP
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCC
DFENRFGLDIFAFGHAGDGNIHLILTVPRAARPDTQAPRLEDGIEAVARRVLELGGTISG
CCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
EHGVGEAKKHLLPLEIAPASLRLQRGIKQLFDPCNIMNPGKVFP
CCCCCHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TCTTTPDLDRIAEELTAILGPQGVLTAPGEPYDRDSSPFTAAPDIVALPETTEQVSRIV
CCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
RLASRLGFALIPRGAGTGTAGGCLPLSGGVVISLERMKRIITLDTRSLYAHVEAGVITGE
HHHHHCCEEEEECCCCCCCCCCCEEECCCEEEEHHHHHHHHEECCHHHHHHHHCCEEECC
LRDAAAGQGLFFPPDPASLDTSTIGGNVATNAGGPACVKYGVMRDYVLGVEAVMPDGEVI
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
QAGVRTRKGVVGYDMAHLLTGSEGTLGIITSVYLKLIPLPPATVGLAAVFPSLPDAMRTV
HHHHHHCCCCCCCCHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHH
AAVLGRGHLPSAIEFLDHKCLGLVGDKLPFSVEDKSASLLIIELDGRTEAITPEIDMVAA
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCCHHHHHHH
ICTEHGATHLMPGGTRKERDTIWNVRREVSTRIREHAARSFSEDVVVPIGSIASFIAEVP
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCC
DFENRFGLDIFAFGHAGDGNIHLILTVPRAARPDTQAPRLEDGIEAVARRVLELGGTISG
CCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
EHGVGEAKKHLLPLEIAPASLRLQRGIKQLFDPCNIMNPGKVFP
CCCCCHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]