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The map label for this gene is ydcR [H]

Identifier: 78355204

GI number: 78355204

Start: 143232

End: 144665

Strand: Reverse

Name: ydcR [H]

Synonym: Dde_0157

Alternate gene names: 78355204

Gene position: 144665-143232 (Counterclockwise)

Preceding gene: 78355207

Following gene: 78355203

Centisome position: 3.88

GC content: 60.46

Gene sequence:

>1434_bases
ATGGAAACACCCCGCCGCGAAGCCTTCCGATACCATGAAGTGGAGCAGCACGTCCTGCGTCTCATCGATTCCAAGCAATA
TCCGCCGGGTTCCCGCCTGCCCTCTCTGCGGGCTGTGGCGCGCACGCTGAGCGCCAGCCTGGCAACGGTGTGCCATGCCT
ACGAAGAGCTTGAGCGTCGCGGGGTTGTGGAATCGCGCCCGAGGTCGGGCTATTATGTGCGCACGCTGCCCAGCCCTCTG
CCTGTGCCGCACAGCGCTCCGGCAGAAGAGGAAGAACCCCGCGAGGCAAACCGCAGCCGGCTTATTGCCACCGTGCTTGA
AGCCGTGGGCAATCCGCAGATGGCTCCTTTCGGCGTGGTAAGCCCCGACCCTTCGCTGCTGCCCGGCAAAAAGCTGGGGC
AGATACTGGCTGAACTGAGCCGGCGCAATGCGGAACAATGCGTAGCGTATGAAACCATTGCAGGCAATGCGGAATACCGC
AGGCAGATCGCAAAGCGCGCCTGCGAAGACGGCATGCCCACACGCGCCTCCGAGGTGGTGGCCACCACAGGCGCCATGGA
AGCATTGTACATCGCGCTGCGGGTACTCACCCGTCCCGGCGACAATGTACTTATCCAGTCGCCCACATACTACTGTTTCC
TGCAGCTGCTCGAAACATTGGGCCTGCGTGCTGTGGAAATTCCTTCCGACCCCAAGCACGGCATAAACCCGGCAGACCTC
ACCAAGGCGCTTTCCACGTTTGAGGTGGCCGCCTGCATTCTTTCAGGCAACTTCAACAACCCCGACGGAGCGCTGACGCC
CGACGCAGCCAAACGCGAGATTGTCGACATACTGGCCGCACGCGGTATCCCGCTGGTTGACGACGATGTGTCCGCTGATC
TGCACTTCGATGCGCAGCGCCCTGCGTCATTCAAACAGTATGACAAAAAAGGGCTTGTTGTGTTCTGTTCTTCGTTTTCA
AAAACCATTGCACCGGGATACCGCGCCGGATGGATGCTGCCCGGCCGCTTTATGGAAAAAGCTCTGGAGGTGAAGGCAAC
CACCAATGTGTGCTGCGCCACCCCCACGCAGGCAGCCGTCGGCGAATTCATGCGGCTGGGGCTGTACGACAGACAGCTGA
AAAAATTGCGCTCCGCCTTTCAGACACAGATATGCGCCATGCATGAATGCATCGGTTCCGCCTTTCCCGACGGAACGCGT
GTAACCAGCCCCCGCGGCGGCGGTGTACTGTGGGTGGAACTGCCTGCCGCCGTCAACGGCGTTGAGCTGTTTTTTAAAGC
CCGGGCCCGCCGTGTGGGCATTGCCCCCGGCTCAATATTTTCCACCCGTGACCGCTTTTCAAACTATATCAGGCTGTCAT
GCTGCGGTATCTGGAACCCCAGAATGGAAGAAGCACTGCGCGATCTGGGGCGGCTGGCACGCGAGCTGACCTGA

Upstream 100 bases:

>100_bases
GCGCACCACACCGGCATTCTCAGCTTGACGGAGCAATTCAAACACAGATACAATTTTCAGAACAGATACAGTTTTTACAA
AATTCGATAAGTACAGAATA

Downstream 100 bases:

>100_bases
ACCGCAACCGCACGGCACCGACCGCTGTTGCGTATCGCCTGACCGCATTGCGGTTTTCTTATCCACAGCTGCCGCACACG
CTCAGTCTGCGGCAGCCTGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
METPRREAFRYHEVEQHVLRLIDSKQYPPGSRLPSLRAVARTLSASLATVCHAYEELERRGVVESRPRSGYYVRTLPSPL
PVPHSAPAEEEEPREANRSRLIATVLEAVGNPQMAPFGVVSPDPSLLPGKKLGQILAELSRRNAEQCVAYETIAGNAEYR
RQIAKRACEDGMPTRASEVVATTGAMEALYIALRVLTRPGDNVLIQSPTYYCFLQLLETLGLRAVEIPSDPKHGINPADL
TKALSTFEVAACILSGNFNNPDGALTPDAAKREIVDILAARGIPLVDDDVSADLHFDAQRPASFKQYDKKGLVVFCSSFS
KTIAPGYRAGWMLPGRFMEKALEVKATTNVCCATPTQAAVGEFMRLGLYDRQLKKLRSAFQTQICAMHECIGSAFPDGTR
VTSPRGGGVLWVELPAAVNGVELFFKARARRVGIAPGSIFSTRDRFSNYIRLSCCGIWNPRMEEALRDLGRLARELT

Sequences:

>Translated_477_residues
METPRREAFRYHEVEQHVLRLIDSKQYPPGSRLPSLRAVARTLSASLATVCHAYEELERRGVVESRPRSGYYVRTLPSPL
PVPHSAPAEEEEPREANRSRLIATVLEAVGNPQMAPFGVVSPDPSLLPGKKLGQILAELSRRNAEQCVAYETIAGNAEYR
RQIAKRACEDGMPTRASEVVATTGAMEALYIALRVLTRPGDNVLIQSPTYYCFLQLLETLGLRAVEIPSDPKHGINPADL
TKALSTFEVAACILSGNFNNPDGALTPDAAKREIVDILAARGIPLVDDDVSADLHFDAQRPASFKQYDKKGLVVFCSSFS
KTIAPGYRAGWMLPGRFMEKALEVKATTNVCCATPTQAAVGEFMRLGLYDRQLKKLRSAFQTQICAMHECIGSAFPDGTR
VTSPRGGGVLWVELPAAVNGVELFFKARARRVGIAPGSIFSTRDRFSNYIRLSCCGIWNPRMEEALRDLGRLARELT
>Mature_477_residues
METPRREAFRYHEVEQHVLRLIDSKQYPPGSRLPSLRAVARTLSASLATVCHAYEELERRGVVESRPRSGYYVRTLPSPL
PVPHSAPAEEEEPREANRSRLIATVLEAVGNPQMAPFGVVSPDPSLLPGKKLGQILAELSRRNAEQCVAYETIAGNAEYR
RQIAKRACEDGMPTRASEVVATTGAMEALYIALRVLTRPGDNVLIQSPTYYCFLQLLETLGLRAVEIPSDPKHGINPADL
TKALSTFEVAACILSGNFNNPDGALTPDAAKREIVDILAARGIPLVDDDVSADLHFDAQRPASFKQYDKKGLVVFCSSFS
KTIAPGYRAGWMLPGRFMEKALEVKATTNVCCATPTQAAVGEFMRLGLYDRQLKKLRSAFQTQICAMHECIGSAFPDGTR
VTSPRGGGVLWVELPAAVNGVELFFKARARRVGIAPGSIFSTRDRFSNYIRLSCCGIWNPRMEEALRDLGRLARELT

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=327, Percent_Identity=23.5474006116208, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI33469970, Length=327, Percent_Identity=23.5474006116208, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4507369, Length=229, Percent_Identity=22.707423580786, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787710, Length=467, Percent_Identity=33.8329764453961, Blast_Score=284, Evalue=7e-78,
Organism=Escherichia coli, GI1790797, Length=467, Percent_Identity=32.9764453961456, Blast_Score=271, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6321000, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356535, Length=359, Percent_Identity=24.7910863509749, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52478; Mature: 52478

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METPRREAFRYHEVEQHVLRLIDSKQYPPGSRLPSLRAVARTLSASLATVCHAYEELERR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVVESRPRSGYYVRTLPSPLPVPHSAPAEEEEPREANRSRLIATVLEAVGNPQMAPFGVV
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SPDPSLLPGKKLGQILAELSRRNAEQCVAYETIAGNAEYRRQIAKRACEDGMPTRASEVV
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHH
ATTGAMEALYIALRVLTRPGDNVLIQSPTYYCFLQLLETLGLRAVEIPSDPKHGINPADL
HHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
TKALSTFEVAACILSGNFNNPDGALTPDAAKREIVDILAARGIPLVDDDVSADLHFDAQR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
PASFKQYDKKGLVVFCSSFSKTIAPGYRAGWMLPGRFMEKALEVKATTNVCCATPTQAAV
CCHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHH
GEFMRLGLYDRQLKKLRSAFQTQICAMHECIGSAFPDGTRVTSPRGGGVLWVELPAAVNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCHHHH
VELFFKARARRVGIAPGSIFSTRDRFSNYIRLSCCGIWNPRMEEALRDLGRLARELT
HHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
METPRREAFRYHEVEQHVLRLIDSKQYPPGSRLPSLRAVARTLSASLATVCHAYEELERR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVVESRPRSGYYVRTLPSPLPVPHSAPAEEEEPREANRSRLIATVLEAVGNPQMAPFGVV
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SPDPSLLPGKKLGQILAELSRRNAEQCVAYETIAGNAEYRRQIAKRACEDGMPTRASEVV
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHH
ATTGAMEALYIALRVLTRPGDNVLIQSPTYYCFLQLLETLGLRAVEIPSDPKHGINPADL
HHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
TKALSTFEVAACILSGNFNNPDGALTPDAAKREIVDILAARGIPLVDDDVSADLHFDAQR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
PASFKQYDKKGLVVFCSSFSKTIAPGYRAGWMLPGRFMEKALEVKATTNVCCATPTQAAV
CCHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHH
GEFMRLGLYDRQLKKLRSAFQTQICAMHECIGSAFPDGTRVTSPRGGGVLWVELPAAVNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCHHHH
VELFFKARARRVGIAPGSIFSTRDRFSNYIRLSCCGIWNPRMEEALRDLGRLARELT
HHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]