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The map label for this gene is cysQ [H]

Identifier: 78355170

GI number: 78355170

Start: 115815

End: 116588

Strand: Reverse

Name: cysQ [H]

Synonym: Dde_0123

Alternate gene names: 78355170

Gene position: 116588-115815 (Counterclockwise)

Preceding gene: 78355172

Following gene: 78355168

Centisome position: 3.13

GC content: 61.76

Gene sequence:

>774_bases
ATGTTTGAAAACGTACCCCTGAGCGGGATGATCCGCATAGCCAGACAGGCGGGAAAAGAAATCGCCGCCCGTCAGCAGGC
CATTGTGCAGGCAGGTGAAGCCGCCATATGGCACAAGGACGACGACTCGCCCGTCACTCAGGCGGACAGGGCGGCCAGTG
CCGTTCTGTGTGCCGGACTGGCACAGATGGCTCCTTCTGTTCCCGTTATTTCAGAAGAGGAATCCATTCCCCCTGCCGAG
GTACGACGGGGCTGGGGGCTGTATTTTCTGGTGGACCCGCTGGACGGCACCAAAGGCTATCTGAAAGGAGAGGCAGACTA
CAGTGTCTGTGTGGCACTCATGCGCCGCGACATGCCTCTGGCCGGAGTTGTCCATGTGCCTGCGCGCGGGCTTACCTATT
ACGGTCTGCCCGGCACGGGCGCATGGCGCGAAGATGAAAGCGGCATGCCGGTGCGCCTGCATACCGCCCCCGCCGTTTCA
GGAAAACAACCGGTGGTGCTGCAAAGCCGGGTGTCCGCAACCCCCAAACTGGATGCCTACATGGATGGTCTGCCCCATAC
GCGCCTGATGGCAGGCAGTGCCTACAAGTTCTGCCTGCTGGCCGAGGGAACGGCCCAGATGTATCCCTGTCTGCACCCCA
CATGGGAATGGGACACCGCCGCCGGAGAAGCCGTTCTGCGCGGAGCGGGCGGCACTGTGACCGATATGGACGGCCGCCCC
CTCAGATACGGCAAAAGCTCTCTGCTCAACGATCTTTTCATAGCGCGGGGATGA

Upstream 100 bases:

>100_bases
TACGGACAGCCCTGAGACGGCATGGCAGTGACAGATTACACATGAGGTATTATTACCAGTAAGATGGACGCATAGCCAGC
TTGTATCCCCGGAGCACGCC

Downstream 100 bases:

>100_bases
TCAGCGCTCCGCCCACAAGGCACGGCGCCCCTTGATACGCAGCCTGCCCAGCGGCAGCCCTCTGAAATACAGTCCGGCCT
CCGGCAGGGATGCATCCACG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MFENVPLSGMIRIARQAGKEIAARQQAIVQAGEAAIWHKDDDSPVTQADRAASAVLCAGLAQMAPSVPVISEEESIPPAE
VRRGWGLYFLVDPLDGTKGYLKGEADYSVCVALMRRDMPLAGVVHVPARGLTYYGLPGTGAWREDESGMPVRLHTAPAVS
GKQPVVLQSRVSATPKLDAYMDGLPHTRLMAGSAYKFCLLAEGTAQMYPCLHPTWEWDTAAGEAVLRGAGGTVTDMDGRP
LRYGKSSLLNDLFIARG

Sequences:

>Translated_257_residues
MFENVPLSGMIRIARQAGKEIAARQQAIVQAGEAAIWHKDDDSPVTQADRAASAVLCAGLAQMAPSVPVISEEESIPPAE
VRRGWGLYFLVDPLDGTKGYLKGEADYSVCVALMRRDMPLAGVVHVPARGLTYYGLPGTGAWREDESGMPVRLHTAPAVS
GKQPVVLQSRVSATPKLDAYMDGLPHTRLMAGSAYKFCLLAEGTAQMYPCLHPTWEWDTAAGEAVLRGAGGTVTDMDGRP
LRYGKSSLLNDLFIARG
>Mature_257_residues
MFENVPLSGMIRIARQAGKEIAARQQAIVQAGEAAIWHKDDDSPVTQADRAASAVLCAGLAQMAPSVPVISEEESIPPAE
VRRGWGLYFLVDPLDGTKGYLKGEADYSVCVALMRRDMPLAGVVHVPARGLTYYGLPGTGAWREDESGMPVRLHTAPAVS
GKQPVVLQSRVSATPKLDAYMDGLPHTRLMAGSAYKFCLLAEGTAQMYPCLHPTWEWDTAAGEAVLRGAGGTVTDMDGRP
LRYGKSSLLNDLFIARG

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=250, Percent_Identity=41.6, Blast_Score=143, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995905, Length=166, Percent_Identity=33.7349397590361, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71995897, Length=166, Percent_Identity=33.7349397590361, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537869, Length=281, Percent_Identity=25.2669039145907, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=209, Percent_Identity=25.8373205741627, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202572, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651149, Length=271, Percent_Identity=26.5682656826568, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641722, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27568; Mature: 27568

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENVPLSGMIRIARQAGKEIAARQQAIVQAGEAAIWHKDDDSPVTQADRAASAVLCAGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
AQMAPSVPVISEEESIPPAEVRRGWGLYFLVDPLDGTKGYLKGEADYSVCVALMRRDMPL
HHHCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCC
AGVVHVPARGLTYYGLPGTGAWREDESGMPVRLHTAPAVSGKQPVVLQSRVSATPKLDAY
EEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHH
MDGLPHTRLMAGSAYKFCLLAEGTAQMYPCLHPTWEWDTAAGEAVLRGAGGTVTDMDGRP
HCCCCCCEEECCCCEEEEEEECCHHHHCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCC
LRYGKSSLLNDLFIARG
CHHCHHHHHHHHHHCCC
>Mature Secondary Structure
MFENVPLSGMIRIARQAGKEIAARQQAIVQAGEAAIWHKDDDSPVTQADRAASAVLCAGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
AQMAPSVPVISEEESIPPAEVRRGWGLYFLVDPLDGTKGYLKGEADYSVCVALMRRDMPL
HHHCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCC
AGVVHVPARGLTYYGLPGTGAWREDESGMPVRLHTAPAVSGKQPVVLQSRVSATPKLDAY
EEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHH
MDGLPHTRLMAGSAYKFCLLAEGTAQMYPCLHPTWEWDTAAGEAVLRGAGGTVTDMDGRP
HCCCCCCEEECCCCEEEEEEECCHHHHCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCC
LRYGKSSLLNDLFIARG
CHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]