Click here to switch to the map view.

The map label for this gene is prmA

Identifier: 78224576

GI number: 78224576

Start: 3800046

End: 3800945

Strand: Direct

Name: prmA

Synonym: Gmet_3386

Alternate gene names: 78224576

Gene position: 3800046-3800945 (Clockwise)

Preceding gene: 78224568

Following gene: 78224577

Centisome position: 95.06

GC content: 66.11

Gene sequence:

>900_bases
ATGGACAAAACCTGGGCCGAAGTCACCTGCGAGATCCCCGCGGCAATGATCGACCTTCTGGCCGACTTCCTCGTGGAACT
CTCCGGCAACGGAGTGAGCATCGACAATCTGGAGTTGGACACCTTCTCCCTCGACACCATGGACGAGGCGCCGGTGAAGA
CCGTGCGGGCCTACTTCACTCCCGACGACGAACTGGAAGAAAAACTGGCCGCCCTGAACCGGTTCATCCAGGAGCACGCG
CCCGCCTACGGCGACGCCGCTCCAGCCCCGCCCACCGTCACCACCCTCAGGGAGGAGGACTGGGCCACGGGGTGGCGCCA
GCACTTCGCACCGACCCGCATCGGCCGAAAACTCGTGATCAAGCCCACCTGGGAGCCGTTCTCGCCGGAGCCCGGCGACT
TAGTCATCGAACTGGACCCGGGGATGGCCTTCGGCACCGGCACCCATCCCACCACCCGCCTCTGCCTGGAGGCCCTGGAA
AAGCTCGGCACCGCCGGCGATGTCCTCGACGTGGGGACCGGCTCGGGAATCCTGGCCATGGCCGCCGTCAAGCTGGGGGC
GCAACGCGTCGTGGGGACCGACATCGACCCCGACGCCGTGGCAGTGGCCCGGGAAAACTGCGCCATGAACGGGGTCACCG
CCGAACTGGTCACCACTCCCCTGGCGGATATCCCGGGGCAATTCTCCGTGGTCCTCGCCAACATCCTTGCCGAGGACCTG
GTGAGGATGGCGGCCGACCTGACGGCAAAGGTCGCCCCCGGCGGCTTCCTGATCCTGTCCGGAATTCTCGTGGAGCGCGA
GTCCTACGTCATTGACGGCTTTGTCTCCACCGGCCTTACCCTTGCCGAAACCACCCGCGAGGGGGAGTGGAGCTGCCTCC
TCTATCAGGCCGGACAATGA

Upstream 100 bases:

>100_bases
GACGGGTATTTGTCAAGGTTTTTATTGTCAAAGCCCTTTAGTTTTGCTACGTTGGCCCACCTTGACTGAATCAATCCAAA
CGCAACTCCGAGGAGCATCC

Downstream 100 bases:

>100_bases
GCGTCCGCCGCTTCATGGCCCCCGGCGCCGACCTCGCCGGAGAGTCGGTGCGGATCGAGGGGGACCTTTTCCGTCACATG
GTGAAGGTCCTGCGCCTGAA

Product: 50S ribosomal protein L11P methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDKTWAEVTCEIPAAMIDLLADFLVELSGNGVSIDNLELDTFSLDTMDEAPVKTVRAYFTPDDELEEKLAALNRFIQEHA
PAYGDAAPAPPTVTTLREEDWATGWRQHFAPTRIGRKLVIKPTWEPFSPEPGDLVIELDPGMAFGTGTHPTTRLCLEALE
KLGTAGDVLDVGTGSGILAMAAVKLGAQRVVGTDIDPDAVAVARENCAMNGVTAELVTTPLADIPGQFSVVLANILAEDL
VRMAADLTAKVAPGGFLILSGILVERESYVIDGFVSTGLTLAETTREGEWSCLLYQAGQ

Sequences:

>Translated_299_residues
MDKTWAEVTCEIPAAMIDLLADFLVELSGNGVSIDNLELDTFSLDTMDEAPVKTVRAYFTPDDELEEKLAALNRFIQEHA
PAYGDAAPAPPTVTTLREEDWATGWRQHFAPTRIGRKLVIKPTWEPFSPEPGDLVIELDPGMAFGTGTHPTTRLCLEALE
KLGTAGDVLDVGTGSGILAMAAVKLGAQRVVGTDIDPDAVAVARENCAMNGVTAELVTTPLADIPGQFSVVLANILAEDL
VRMAADLTAKVAPGGFLILSGILVERESYVIDGFVSTGLTLAETTREGEWSCLLYQAGQ
>Mature_299_residues
MDKTWAEVTCEIPAAMIDLLADFLVELSGNGVSIDNLELDTFSLDTMDEAPVKTVRAYFTPDDELEEKLAALNRFIQEHA
PAYGDAAPAPPTVTTLREEDWATGWRQHFAPTRIGRKLVIKPTWEPFSPEPGDLVIELDPGMAFGTGTHPTTRLCLEALE
KLGTAGDVLDVGTGSGILAMAAVKLGAQRVVGTDIDPDAVAVARENCAMNGVTAELVTTPLADIPGQFSVVLANILAEDL
VRMAADLTAKVAPGGFLILSGILVERESYVIDGFVSTGLTLAETTREGEWSCLLYQAGQ

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=172, Percent_Identity=44.1860465116279, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_GEOMG (Q39Q76)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386323.1
- ProteinModelPortal:   Q39Q76
- SMR:   Q39Q76
- STRING:   Q39Q76
- GeneID:   3740701
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3386
- NMPDR:   fig|269799.3.peg.3361
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   AVDIEPW
- PhylomeDB:   Q39Q76
- ProtClustDB:   CLSK827836
- BioCyc:   GMET269799:GMET_3386-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31945; Mature: 31945

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTWAEVTCEIPAAMIDLLADFLVELSGNGVSIDNLELDTFSLDTMDEAPVKTVRAYFT
CCCCHHHEEECCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCHHHEEEECC
PDDELEEKLAALNRFIQEHAPAYGDAAPAPPTVTTLREEDWATGWRQHFAPTRIGRKLVI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCHHHHCCEEEE
KPTWEPFSPEPGDLVIELDPGMAFGTGTHPTTRLCLEALEKLGTAGDVLDVGTGSGILAM
ECCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHH
AAVKLGAQRVVGTDIDPDAVAVARENCAMNGVTAELVTTPLADIPGQFSVVLANILAEDL
HHHHHCCHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHH
VRMAADLTAKVAPGGFLILSGILVERESYVIDGFVSTGLTLAETTREGEWSCLLYQAGQ
HHHHHHHHHCCCCCCEEEHHHHHHCCCCEEEEHHHHCCEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MDKTWAEVTCEIPAAMIDLLADFLVELSGNGVSIDNLELDTFSLDTMDEAPVKTVRAYFT
CCCCHHHEEECCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCHHHEEEECC
PDDELEEKLAALNRFIQEHAPAYGDAAPAPPTVTTLREEDWATGWRQHFAPTRIGRKLVI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCHHHHCCEEEE
KPTWEPFSPEPGDLVIELDPGMAFGTGTHPTTRLCLEALEKLGTAGDVLDVGTGSGILAM
ECCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHH
AAVKLGAQRVVGTDIDPDAVAVARENCAMNGVTAELVTTPLADIPGQFSVVLANILAEDL
HHHHHCCHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHH
VRMAADLTAKVAPGGFLILSGILVERESYVIDGFVSTGLTLAETTREGEWSCLLYQAGQ
HHHHHHHHHCCCCCCEEEHHHHHHCCCCEEEEHHHHCCEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA