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The map label for this gene is yfbQ [C]

Identifier: 78224516

GI number: 78224516

Start: 3740078

End: 3741382

Strand: Reverse

Name: yfbQ [C]

Synonym: Gmet_3325

Alternate gene names: 78224516

Gene position: 3741382-3740078 (Counterclockwise)

Preceding gene: 78224517

Following gene: 78224500

Centisome position: 93.59

GC content: 61.46

Gene sequence:

>1305_bases
GTGAGAAACGAACTGGTGACGCCCGGAGCGGGCGAACTGACCTACGAGATCCGCAACATCGTCAACGTGGCGGAGAAGCT
CCAGAAGCACGGGGTGAAGATCAACTGGGAGAACATTGGCGACCCGATCGTCAAGGGGGAGGAGATTCCCCGCTGGATGA
AGGAGATCGTGGCCAATGAGGTGATGGAGAATGACACCTGGGGCTACTGCCACACCCGGGGGGTCCTGGAGACCCGGGAG
TTCATCTGCGGCCTCACCAACAACCGCGGCGGTGCCCGGATCACCCCCGACGACATCATCTTCTTCAACGGCCTCGGCGA
CGCCATCTCCACGGTCTACGGCAACCTCCGCCACGAAAGCCGCATCCTCATGCCGTCCCCTACCTACACCACCCACTCCA
TCGGCGAGGCGGCCCACGCCCAGGCCTCGCCGGTCTGCTACCGGCTTGACCCGGCCAACAACTGGTTCCCCGACCTGGAG
GACATGGAGAACCATGTCCGGTACAATCCCCAGATTTCCGGCATCCTCCTCATCAACCCCGACAACCCCACCGGCATGGT
CTTCTCCAGGGAGACCCTGGAGAAGATCGTCGCTATCGCCCGGAAATACGAGCTCTTCATCATCGCCGACGAGGTCTACA
ACAACATCACCTACAACGGCCAGACCACCGTCCCCATCTCCGACGTTATCGGCGACGTGCCGGCCATCGCCATGAAGGGG
ATCTCCAAGGAGATACCCTGGCCCGGCTCCCGCTGCGGCTGGATCGAGGTCTACAACGGCGCTAAGGATGACCAGTTCCG
CAAGTACATCAACTCCATCCTCTCCGCCAAGATGAACGAGGTCTGCTCCACCACCCTGCCGCAGAAGTGCATCCCGGCTA
TCATGAAACACCCGGAATACCAGACCTACCTCCAGGAGCGGATCAGGCGCTATGAGAAGATGAGCACCATCACCTTCGAC
TGCCTCAGGGAAGTTCCCGAACTCATGGTGAACCGGACTAACGGCGCCTTCTACATGTCCGTGGCCTTCCGGGATGGCCT
TCTCACCAACGGCCAGTCCCTCCCCATCGAGAACGCCGAGGTGCGGGAGCTGGTGGAAGGGCTCGTGAACGCCCCCGGCG
TCTCCCCGGACAAGCGGTTCGTCTACTACCTCCTGGCCAGCACCGGCATCTGCATCGTGCCGCTCTCCTCCTTCAATACG
CCGCTGCAGGGGTTCCGGGTGACCCTCCTGGAGAAGGACGAGGCCGAATGCCTTCGGATCTACCAGACCCTGGCGAAGAA
GATTGCGGAGTATCTGAAGTCCTGA

Upstream 100 bases:

>100_bases
GCGTCGTAACGCTTCGTGTATCATCAAAGGCCGTGGGTACCTCCCACGGCCTTTACCATTTTCAGGACCATCACCAACAG
AGAGAAAAGAGGGAGATGAC

Downstream 100 bases:

>100_bases
CACAGGGTTCTTCAGGGAGTGGTGATGAAAAAGGGGGAGCTGACTGCCGGCTCCCCCTTTTTTTGTCCCGCATTGGCTGC
TTTTATTGCCCCGCCGCCCT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKGEEIPRWMKEIVANEVMENDTWGYCHTRGVLETRE
FICGLTNNRGGARITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQASPVCYRLDPANNWFPDLE
DMENHVRYNPQISGILLINPDNPTGMVFSRETLEKIVAIARKYELFIIADEVYNNITYNGQTTVPISDVIGDVPAIAMKG
ISKEIPWPGSRCGWIEVYNGAKDDQFRKYINSILSAKMNEVCSTTLPQKCIPAIMKHPEYQTYLQERIRRYEKMSTITFD
CLREVPELMVNRTNGAFYMSVAFRDGLLTNGQSLPIENAEVRELVEGLVNAPGVSPDKRFVYYLLASTGICIVPLSSFNT
PLQGFRVTLLEKDEAECLRIYQTLAKKIAEYLKS

Sequences:

>Translated_434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKGEEIPRWMKEIVANEVMENDTWGYCHTRGVLETRE
FICGLTNNRGGARITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQASPVCYRLDPANNWFPDLE
DMENHVRYNPQISGILLINPDNPTGMVFSRETLEKIVAIARKYELFIIADEVYNNITYNGQTTVPISDVIGDVPAIAMKG
ISKEIPWPGSRCGWIEVYNGAKDDQFRKYINSILSAKMNEVCSTTLPQKCIPAIMKHPEYQTYLQERIRRYEKMSTITFD
CLREVPELMVNRTNGAFYMSVAFRDGLLTNGQSLPIENAEVRELVEGLVNAPGVSPDKRFVYYLLASTGICIVPLSSFNT
PLQGFRVTLLEKDEAECLRIYQTLAKKIAEYLKS
>Mature_434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKGEEIPRWMKEIVANEVMENDTWGYCHTRGVLETRE
FICGLTNNRGGARITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQASPVCYRLDPANNWFPDLE
DMENHVRYNPQISGILLINPDNPTGMVFSRETLEKIVAIARKYELFIIADEVYNNITYNGQTTVPISDVIGDVPAIAMKG
ISKEIPWPGSRCGWIEVYNGAKDDQFRKYINSILSAKMNEVCSTTLPQKCIPAIMKHPEYQTYLQERIRRYEKMSTITFD
CLREVPELMVNRTNGAFYMSVAFRDGLLTNGQSLPIENAEVRELVEGLVNAPGVSPDKRFVYYLLASTGICIVPLSSFNT
PLQGFRVTLLEKDEAECLRIYQTLAKKIAEYLKS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=314, Percent_Identity=25.4777070063694, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI19263340, Length=376, Percent_Identity=25.7978723404255, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI215599424, Length=375, Percent_Identity=25.6, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI4885351, Length=362, Percent_Identity=25.9668508287293, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788627, Length=331, Percent_Identity=29.9093655589124, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788722, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=315, Percent_Identity=31.1111111111111, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=437, Percent_Identity=24.7139588100687, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320317, Length=371, Percent_Identity=27.7628032345013, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323118, Length=375, Percent_Identity=24.2666666666667, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859735, Length=339, Percent_Identity=26.5486725663717, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=22.8643216080402, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49030; Mature: 49030

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKGEEIPRWMKEIVANE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
VMENDTWGYCHTRGVLETREFICGLTNNRGGARITPDDIIFFNGLGDAISTVYGNLRHES
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCC
RILMPSPTYTTHSIGEAAHAQASPVCYRLDPANNWFPDLEDMENHVRYNPQISGILLINP
EEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCEECCCCCEEEEECC
DNPTGMVFSRETLEKIVAIARKYELFIIADEVYNNITYNGQTTVPISDVIGDVPAIAMKG
CCCCCEEEEHHHHHHHHHHHHHCEEEEEEHHHHCCEEECCEECCCHHHHHCCHHHHHHHC
ISKEIPWPGSRCGWIEVYNGAKDDQFRKYINSILSAKMNEVCSTTLPQKCIPAIMKHPEY
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
QTYLQERIRRYEKMSTITFDCLREVPELMVNRTNGAFYMSVAFRDGLLTNGQSLPIENAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHH
VRELVEGLVNAPGVSPDKRFVYYLLASTGICIVPLSSFNTPLQGFRVTLLEKDEAECLRI
HHHHHHHHHCCCCCCCCHHEEEEEECCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
YQTLAKKIAEYLKS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKGEEIPRWMKEIVANE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
VMENDTWGYCHTRGVLETREFICGLTNNRGGARITPDDIIFFNGLGDAISTVYGNLRHES
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCC
RILMPSPTYTTHSIGEAAHAQASPVCYRLDPANNWFPDLEDMENHVRYNPQISGILLINP
EEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCEECCCCCEEEEECC
DNPTGMVFSRETLEKIVAIARKYELFIIADEVYNNITYNGQTTVPISDVIGDVPAIAMKG
CCCCCEEEEHHHHHHHHHHHHHCEEEEEEHHHHCCEEECCEECCCHHHHHCCHHHHHHHC
ISKEIPWPGSRCGWIEVYNGAKDDQFRKYINSILSAKMNEVCSTTLPQKCIPAIMKHPEY
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
QTYLQERIRRYEKMSTITFDCLREVPELMVNRTNGAFYMSVAFRDGLLTNGQSLPIENAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHH
VRELVEGLVNAPGVSPDKRFVYYLLASTGICIVPLSSFNTPLQGFRVTLLEKDEAECLRI
HHHHHHHHHCCCCCCCCHHEEEEEECCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
YQTLAKKIAEYLKS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]