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The map label for this gene is fabH [H]

Identifier: 78224463

GI number: 78224463

Start: 3680901

End: 3681881

Strand: Reverse

Name: fabH [H]

Synonym: Gmet_3272

Alternate gene names: 78224463

Gene position: 3681881-3680901 (Counterclockwise)

Preceding gene: 78224464

Following gene: 78224461

Centisome position: 92.11

GC content: 62.49

Gene sequence:

>981_bases
ATGATTTATGCCGAAATCGTGGCAACAGGCGGGTGCGTTCCCGAGCGGGTCGTTCCCAATGATTTTTTCAACTACCTCGT
GGATGACGCCGACACCTGGATCGCATCCCGTACGGGAATCCGGGAGCGCCGCTTCGCGTCTCCCAAGGAGTCCACCTCTG
ACCTGGCCACCGCCGCGGCCCGCAGTGCCCTCGCCCGGGCCAACATGGAACCGGGCGAGCTCGACTGCATCATCGTAGGC
ACCTCGACCCCCGACATGTATCTCCCCGCCACCGCCTGCATGGTCCAGAAAAACATCGGCGCCAAAAACGCCGTTGCCTT
CGACATGAACGCCGTCTGCAGCGGCTTCATCTTCGGCGTGGAAACGGCCGACAACTTCATCCGCTCCGGCAAGTACCGAC
GGGTCATGGTGATCGGCGCCGACACCTATTCGAAGATCCTCGACTTCGATGACAAGGGGACCTGCCCCCTTTTCGGCGAC
GGAGCCAGCGCCGTCATCCTTGGCGCCACCGAGGAGAAGCGGGGAATCCTCCAGAGCATGATCTTCAGCGACGGCGGCGG
GTGGGAGCTGATCCAGGTCCCCTCGTCGGGTTCCCGGTGTCCGGTCACCGCAGAGACTATCGCCGCTCACGACAACACCT
TCAAAATGTCGGGCAAGCAGGTTTTCGTCTTCGCCACCGACGTCATCCCCCGGATCATCGAACAGGTCACCACCAGGGCA
GGGGTGAGCGTCGGCGACCTCGACTACATCATCCCCCACCAGGCCAATGTCCGGATTATCGACTTCATCTCCAAGAAGAC
CGGTCTCGGCAAGGAGCGGTTCCTTCTGAACCTGGACCGCTATGGCAACACGGCTGCCGCCTCGGTGGGGCTTGCCCTGG
ACGAGAACCTCCGTAACGGCACCCTCAAGCCGGGGCAGCTGGTCCTCATCATGGGATTCGGCGGTGGACTTTCCTGGGGA
GGCGCCCTTATCCGCCTCTGA

Upstream 100 bases:

>100_bases
TTTGACAAAATCATGTAAACTATGAGATAAACTAACGAGTTAGCATGGAGCCCCCGTTCAGGGGGCTTATGTGTATCACT
GGTCAGAATGGAGCGGTGCG

Downstream 100 bases:

>100_bases
TTCCCGCTATTCCTTCGCCGGCCGTTACCACCGAAAGTCCCTTGCCGGTAAGGATTTCAACGAGCAGCTCTGGCGGCACG
ATCCGCTTCCATCCGTCGTG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIYAEIVATGGCVPERVVPNDFFNYLVDDADTWIASRTGIRERRFASPKESTSDLATAAARSALARANMEPGELDCIIVG
TSTPDMYLPATACMVQKNIGAKNAVAFDMNAVCSGFIFGVETADNFIRSGKYRRVMVIGADTYSKILDFDDKGTCPLFGD
GASAVILGATEEKRGILQSMIFSDGGGWELIQVPSSGSRCPVTAETIAAHDNTFKMSGKQVFVFATDVIPRIIEQVTTRA
GVSVGDLDYIIPHQANVRIIDFISKKTGLGKERFLLNLDRYGNTAAASVGLALDENLRNGTLKPGQLVLIMGFGGGLSWG
GALIRL

Sequences:

>Translated_326_residues
MIYAEIVATGGCVPERVVPNDFFNYLVDDADTWIASRTGIRERRFASPKESTSDLATAAARSALARANMEPGELDCIIVG
TSTPDMYLPATACMVQKNIGAKNAVAFDMNAVCSGFIFGVETADNFIRSGKYRRVMVIGADTYSKILDFDDKGTCPLFGD
GASAVILGATEEKRGILQSMIFSDGGGWELIQVPSSGSRCPVTAETIAAHDNTFKMSGKQVFVFATDVIPRIIEQVTTRA
GVSVGDLDYIIPHQANVRIIDFISKKTGLGKERFLLNLDRYGNTAAASVGLALDENLRNGTLKPGQLVLIMGFGGGLSWG
GALIRL
>Mature_326_residues
MIYAEIVATGGCVPERVVPNDFFNYLVDDADTWIASRTGIRERRFASPKESTSDLATAAARSALARANMEPGELDCIIVG
TSTPDMYLPATACMVQKNIGAKNAVAFDMNAVCSGFIFGVETADNFIRSGKYRRVMVIGADTYSKILDFDDKGTCPLFGD
GASAVILGATEEKRGILQSMIFSDGGGWELIQVPSSGSRCPVTAETIAAHDNTFKMSGKQVFVFATDVIPRIIEQVTTRA
GVSVGDLDYIIPHQANVRIIDFISKKTGLGKERFLLNLDRYGNTAAASVGLALDENLRNGTLKPGQLVLIMGFGGGLSWG
GALIRL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=38.5321100917431, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34925; Mature: 34925

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYAEIVATGGCVPERVVPNDFFNYLVDDADTWIASRTGIRERRFASPKESTSDLATAAA
CEEEEEEECCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
RSALARANMEPGELDCIIVGTSTPDMYLPATACMVQKNIGAKNAVAFDMNAVCSGFIFGV
HHHHHHCCCCCCCEEEEEEECCCCCEECCHHHHHHHHCCCCCCEEEEEHHHHHCEEEEEE
ETADNFIRSGKYRRVMVIGADTYSKILDFDDKGTCPLFGDGASAVILGATEEKRGILQSM
HHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCCCCCEECCCCCEEEEECCHHHHHHHHHH
IFSDGGGWELIQVPSSGSRCPVTAETIAAHDNTFKMSGKQVFVFATDVIPRIIEQVTTRA
HHCCCCCEEEEEECCCCCCCCEEHHHHEECCCEEEECCCEEEEEEHHHHHHHHHHHHHHC
GVSVGDLDYIIPHQANVRIIDFISKKTGLGKERFLLNLDRYGNTAAASVGLALDENLRNG
CCEECCEEEECCCCCCEEEEEEEHHCCCCCCHHEEEEECCCCCHHHHEEEEEECCCCCCC
TLKPGQLVLIMGFGGGLSWGGALIRL
CCCCCCEEEEEECCCCCCCCCEEEEC
>Mature Secondary Structure
MIYAEIVATGGCVPERVVPNDFFNYLVDDADTWIASRTGIRERRFASPKESTSDLATAAA
CEEEEEEECCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
RSALARANMEPGELDCIIVGTSTPDMYLPATACMVQKNIGAKNAVAFDMNAVCSGFIFGV
HHHHHHCCCCCCCEEEEEEECCCCCEECCHHHHHHHHCCCCCCEEEEEHHHHHCEEEEEE
ETADNFIRSGKYRRVMVIGADTYSKILDFDDKGTCPLFGDGASAVILGATEEKRGILQSM
HHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCCCCCEECCCCCEEEEECCHHHHHHHHHH
IFSDGGGWELIQVPSSGSRCPVTAETIAAHDNTFKMSGKQVFVFATDVIPRIIEQVTTRA
HHCCCCCEEEEEECCCCCCCCEEHHHHEECCCEEEECCCEEEEEEHHHHHHHHHHHHHHC
GVSVGDLDYIIPHQANVRIIDFISKKTGLGKERFLLNLDRYGNTAAASVGLALDENLRNG
CCEECCEEEECCCCCCEEEEEEEHHCCCCCCHHEEEEECCCCCHHHHEEEEEECCCCCCC
TLKPGQLVLIMGFGGGLSWGGALIRL
CCCCCCEEEEEECCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]