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The map label for this gene is accD5 [H]

Identifier: 78224439

GI number: 78224439

Start: 3654378

End: 3656102

Strand: Direct

Name: accD5 [H]

Synonym: Gmet_3248

Alternate gene names: 78224439

Gene position: 3654378-3656102 (Clockwise)

Preceding gene: 78224438

Following gene: 78224440

Centisome position: 91.42

GC content: 63.77

Gene sequence:

>1725_bases
ATGTCTAAGAATGCAATCAAACCGCAACTCAAGAACCCGTTTGACCCCCCCGAGAAAGTAGAATTTACCATCCCTGGCGA
AATCTCTCGGACGACCGGCCCCTACGAGGAGGCGATACAGGAGGGATACGACCTCATCCAGCGCCCCATCAAGTCGGTCA
AGATCGACCAGATCGAGAAACAGCACTTCAAGAAGCGGATGACCGTGTGGGAACGCCTCAAGGTCCTCTCCGACCAGGCT
CCCAACGTCCTGTACCAGAACTGGGGCAAGAACCTGGACGGTGCCTCCCTGGTGACCGCCATCATGAATATCGGCGGCCG
CGACGTTGCGGTCTACGGCCATGACTTCACTGTCCGGGCCGGCTCCATCGATGCCACCAACGGGAGCAAGCTGGCCAAGC
TTTTCAACCTGGCCGGCGAGAAGGGGATTCCCCTCATCGGCATGAACGACTCCGCGGGCGCCTTCGTGCCGGCCGGGGTC
GGCGGCCTCGACGGCTACGCCGAGGCATTCACGGCCCTGCGCAAGATCAGCGGCGTGGTCCCCTCCATCATGTGCATGTT
CGGCTTCAACGCCGGCGGCGGCTCCTACCTGCCGCGGCAGGGGAGCTTCGTCATCCAGCCCAACGAGACCTTCTTCGGCC
TCACCGGCCCCGGCGTCGTCAAGTCGGTCCTCGGCGAGGACATCACCCCCGACGAGCTGGGGGGGCCCAAGGTCCACGGC
AGATCGGGCGTAGCCGACCTGACCGTTTCCGATGAACTTGCCGCCCTCCGCACGGCGGTCCGCCTCCTCTCCTACATTCC
CGACAACAACAGCGTGGGGGCTCCATTCCAGAAGACCAGCGATCCCCTGGACCGCAAGACCTGGGAGATCAACACGCTCC
TGAAAAAAGCCTTCAACTCCCCCACCGGCTTCAACACGCCGTTCGACGTCTCCATCATCATCCAGCAGATCTGCGACCAC
GGCGACTACTTCGAGCTCCAGCCCGAGCGGGCCAAGGAAGCGGTCACCGCCTTCGGCCGCCTCGGGGGCCAGGTGGTCGG
CTTCGTGGCCAACAACTCGGCGGTGGCCTCGGGACAGATCGACTGCGACTCGGCGGTGAAGATCGCCCGTTTCGTCCGGT
TCTGCAACATCTACAACATACCCATCATCTTCATGGAAGACACCACCGGCTTCCTGCCGGGGCGCGAACAGGAGAGCCGC
GGCATCGTCCAGGCGGGCCGCTCCATGCTCGACGCCATCGTCGACGTCCGGACCCCGCGGATCCTCCTCATCCTCCGCAA
CGCCTTCGGCGGCGCCTACGCGTCCTACAACAACTACCCCACCGGCGCCGACCTGGTGCTAGCGCTTCCCACCACCCGCC
TCGCCGTCATGGGGCCCGCCGGCAAGGAATTCGTCTACAAGGACGAACTGCGCAAGATTCGCGGAACCGTGGCCGAGATG
GTCAAGAAGGGGACCGAGGAGCGGATCTGTGCCGGCACGGAAGCCGCGGCAGCCAAACGGGATGCCGAGAAGGAAGCCGC
CGAGTGGCTCAAAGGCCAGGAAGCGACCCTGAACCAGCGGTACGAAAAAGAACTGATGAACCCGAAGGAAGGTCTAGCCC
TGGGCTCCATCTCCTCCATCGTCATGCCAACCGACCTGCGCCAGGTCCTGGGCGAAAACATCGCCTTCCTGATGCGGCAC
TACAAGCCGTCGCCCATGTGCGGCCCGCAGCGCGAGTTCCACTAG

Upstream 100 bases:

>100_bases
AATCGTATACATAATCACCTTTAAACGTGCACGGAACTCAACAGGAGGGATTTCGCAATGCGACTGTTGAAAAAATCTAC
CAACCGGAAGGATGGCCGCG

Downstream 100 bases:

>100_bases
ATTATTGAATAACACAGAGACACGGAGGACACGGAGAAAAACCTCTTGAACGGTTTCACCTGCTGTGCCGAGGCTTACCC
CAATTAATGGTTTTAGCCGT

Product: carboxyl transferase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSKNAIKPQLKNPFDPPEKVEFTIPGEISRTTGPYEEAIQEGYDLIQRPIKSVKIDQIEKQHFKKRMTVWERLKVLSDQA
PNVLYQNWGKNLDGASLVTAIMNIGGRDVAVYGHDFTVRAGSIDATNGSKLAKLFNLAGEKGIPLIGMNDSAGAFVPAGV
GGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPNETFFGLTGPGVVKSVLGEDITPDELGGPKVHG
RSGVADLTVSDELAALRTAVRLLSYIPDNNSVGAPFQKTSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDH
GDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASGQIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESR
GIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRGTVAEM
VKKGTEERICAGTEAAAAKRDAEKEAAEWLKGQEATLNQRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRH
YKPSPMCGPQREFH

Sequences:

>Translated_574_residues
MSKNAIKPQLKNPFDPPEKVEFTIPGEISRTTGPYEEAIQEGYDLIQRPIKSVKIDQIEKQHFKKRMTVWERLKVLSDQA
PNVLYQNWGKNLDGASLVTAIMNIGGRDVAVYGHDFTVRAGSIDATNGSKLAKLFNLAGEKGIPLIGMNDSAGAFVPAGV
GGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPNETFFGLTGPGVVKSVLGEDITPDELGGPKVHG
RSGVADLTVSDELAALRTAVRLLSYIPDNNSVGAPFQKTSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDH
GDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASGQIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESR
GIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRGTVAEM
VKKGTEERICAGTEAAAAKRDAEKEAAEWLKGQEATLNQRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRH
YKPSPMCGPQREFH
>Mature_573_residues
SKNAIKPQLKNPFDPPEKVEFTIPGEISRTTGPYEEAIQEGYDLIQRPIKSVKIDQIEKQHFKKRMTVWERLKVLSDQAP
NVLYQNWGKNLDGASLVTAIMNIGGRDVAVYGHDFTVRAGSIDATNGSKLAKLFNLAGEKGIPLIGMNDSAGAFVPAGVG
GLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPNETFFGLTGPGVVKSVLGEDITPDELGGPKVHGR
SGVADLTVSDELAALRTAVRLLSYIPDNNSVGAPFQKTSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHG
DYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASGQIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESRG
IVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRGTVAEMV
KKGTEERICAGTEAAAAKRDAEKEAAEWLKGQEATLNQRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRHY
KPSPMCGPQREFH

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=479, Percent_Identity=35.0730688935282, Blast_Score=262, Evalue=8e-70,
Organism=Homo sapiens, GI295821216, Length=499, Percent_Identity=33.6673346693387, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI11545863, Length=462, Percent_Identity=26.8398268398268, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI134142062, Length=308, Percent_Identity=26.9480519480519, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI38679971, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679974, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679977, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679967, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679960, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=418, Percent_Identity=37.3205741626794, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI25147359, Length=418, Percent_Identity=37.3205741626794, Blast_Score=269, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17552936, Length=496, Percent_Identity=25.4032258064516, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71997163, Length=295, Percent_Identity=24.7457627118644, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133931226, Length=360, Percent_Identity=24.7222222222222, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323863, Length=318, Percent_Identity=24.8427672955975, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324343, Length=318, Percent_Identity=24.5283018867925, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586065, Length=513, Percent_Identity=24.7563352826511, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI161076407, Length=352, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586460, Length=352, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586458, Length=352, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076409, Length=352, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 62462; Mature: 62331

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNAIKPQLKNPFDPPEKVEFTIPGEISRTTGPYEEAIQEGYDLIQRPIKSVKIDQIEK
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHFKKRMTVWERLKVLSDQAPNVLYQNWGKNLDGASLVTAIMNIGGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSIDATNGSKLAKLFNLAGEKGIPLIGMNDSAGAFVPAGVGGLDGYAEAFTALRKISGVV
CCEECCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPNETFFGLTGPGVVKSVLGEDITPDELGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCC
RSGVADLTVSDELAALRTAVRLLSYIPDNNSVGAPFQKTSDPLDRKTWEINTLLKKAFNS
CCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASGQI
CCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCC
DCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESRGIVQAGRSMLDAIVDVRTPR
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCE
ILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRGTVAEM
EEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VKKGTEERICAGTEAAAAKRDAEKEAAEWLKGQEATLNQRYEKELMNPKEGLALGSISSI
HHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCHHHH
VMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKNAIKPQLKNPFDPPEKVEFTIPGEISRTTGPYEEAIQEGYDLIQRPIKSVKIDQIEK
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHFKKRMTVWERLKVLSDQAPNVLYQNWGKNLDGASLVTAIMNIGGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSIDATNGSKLAKLFNLAGEKGIPLIGMNDSAGAFVPAGVGGLDGYAEAFTALRKISGVV
CCEECCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPNETFFGLTGPGVVKSVLGEDITPDELGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCC
RSGVADLTVSDELAALRTAVRLLSYIPDNNSVGAPFQKTSDPLDRKTWEINTLLKKAFNS
CCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASGQI
CCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCC
DCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESRGIVQAGRSMLDAIVDVRTPR
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCE
ILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRGTVAEM
EEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VKKGTEERICAGTEAAAAKRDAEKEAAEWLKGQEATLNQRYEKELMNPKEGLALGSISSI
HHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCHHHH
VMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]