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The map label for this gene is yrvM [H]

Identifier: 78224428

GI number: 78224428

Start: 3643065

End: 3643832

Strand: Direct

Name: yrvM [H]

Synonym: Gmet_3237

Alternate gene names: 78224428

Gene position: 3643065-3643832 (Clockwise)

Preceding gene: 78224427

Following gene: 78224429

Centisome position: 91.14

GC content: 63.8

Gene sequence:

>768_bases
ATGTCACCACTTCACCGCTTTTCCCGCACCGAGATCCTCATCGGCCCCGAGAAGCTCCAGCGGCTCCGCGAGTCGACCGT
GGCCATCTTCGGCCTGGGAGGGGTCGGGAGCTTTGCTGCCGAGGCCCTCTGTCGGGCCGGGGTCGGTCGGCTCGTCCTCG
TGGATTTCGACGACATCTGCCTCACCAACGTAAACCGTCAGCTCCACGCCATGGACGGCACGGTGGGGAAGGCCAAGGTG
CAGGTCATGGCCGAGCGGCTCCGCCTCATCAACCCCGATGCGGACATCGTCCCCCACAAGGATTTCTACGAAGCCGGCAA
CAGCGACTTCCTCCTCTCGGGGGGATACAACTACGTGGTGGACGCCATCGATCACATCACGAGCAAGCTCCACCTGATCC
GCAGCTGCCGGGAGCGGGAACTGCGGATCATCTCCAGCATGGGGGCCGCCAACAAGCTGGACCCCACGAAGATCCGCGTG
GCCGACATCTCCAAGACAAGCGTCTGCGGCCTGGCCAGGGTGGTCCGCAAGCAGTTGCGCAGGCAAGGGATCAAGAGCGG
CGTCACCGTGGTCTACTCCACCGAGGAGCCCCGGGAACAGGCCATTGCCGATGCCGGCTGCCGCTCCAACTGCATCTGCC
CCAACAAGGAGGAACAGCGCTTTTCCTGTGAGCACCGCCGGAACATCCTCGGGAGCATCTCCTTCATCCCGAGCATTTTC
GGGCTCACCATGGCGGGGGTCGTGGTGAACGATCTGGCGAAGGATTGA

Upstream 100 bases:

>100_bases
CCATAACACTTCGAACTTCTACGTCTTTCCCCGTGTGCTCCGTCTCTCCGTGTTATTCAATCAGCCGTTTTCAGGATATT
TTTTGAAACGAGGTATTTCC

Downstream 100 bases:

>100_bases
CACCCGGTTGAAGGTCAACAATTTGCCGCTATACTTTCAACCAGACGCCATCGAATGGGATGAAAGGAGGATACCCGTAT
GACGAGGGAGTATTCGGTTC

Product: UBA/THIF-type NAD/FAD binding fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSPLHRFSRTEILIGPEKLQRLRESTVAIFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHAMDGTVGKAKV
QVMAERLRLINPDADIVPHKDFYEAGNSDFLLSGGYNYVVDAIDHITSKLHLIRSCRERELRIISSMGAANKLDPTKIRV
ADISKTSVCGLARVVRKQLRRQGIKSGVTVVYSTEEPREQAIADAGCRSNCICPNKEEQRFSCEHRRNILGSISFIPSIF
GLTMAGVVVNDLAKD

Sequences:

>Translated_255_residues
MSPLHRFSRTEILIGPEKLQRLRESTVAIFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHAMDGTVGKAKV
QVMAERLRLINPDADIVPHKDFYEAGNSDFLLSGGYNYVVDAIDHITSKLHLIRSCRERELRIISSMGAANKLDPTKIRV
ADISKTSVCGLARVVRKQLRRQGIKSGVTVVYSTEEPREQAIADAGCRSNCICPNKEEQRFSCEHRRNILGSISFIPSIF
GLTMAGVVVNDLAKD
>Mature_254_residues
SPLHRFSRTEILIGPEKLQRLRESTVAIFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHAMDGTVGKAKVQ
VMAERLRLINPDADIVPHKDFYEAGNSDFLLSGGYNYVVDAIDHITSKLHLIRSCRERELRIISSMGAANKLDPTKIRVA
DISKTSVCGLARVVRKQLRRQGIKSGVTVVYSTEEPREQAIADAGCRSNCICPNKEEQRFSCEHRRNILGSISFIPSIFG
LTMAGVVVNDLAKD

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=198, Percent_Identity=42.9292929292929, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1787048, Length=151, Percent_Identity=33.7748344370861, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082356, Length=90, Percent_Identity=44.4444444444444, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=151, Percent_Identity=29.8013245033113, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=263, Percent_Identity=29.6577946768061, Blast_Score=131, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6322825, Length=221, Percent_Identity=33.0316742081448, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24582879, Length=151, Percent_Identity=32.4503311258278, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24660640, Length=135, Percent_Identity=30.3703703703704, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28054; Mature: 27923

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLHRFSRTEILIGPEKLQRLRESTVAIFGLGGVGSFAAEALCRAGVGRLVLVDFDDIC
CCCHHHHCCCEEEECHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHH
LTNVNRQLHAMDGTVGKAKVQVMAERLRLINPDADIVPHKDFYEAGNSDFLLSGGYNYVV
HHCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEECCHHHHH
DAIDHITSKLHLIRSCRERELRIISSMGAANKLDPTKIRVADISKTSVCGLARVVRKQLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
RQGIKSGVTVVYSTEEPREQAIADAGCRSNCICPNKEEQRFSCEHRRNILGSISFIPSIF
HHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLTMAGVVVNDLAKD
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPLHRFSRTEILIGPEKLQRLRESTVAIFGLGGVGSFAAEALCRAGVGRLVLVDFDDIC
CCHHHHCCCEEEECHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHH
LTNVNRQLHAMDGTVGKAKVQVMAERLRLINPDADIVPHKDFYEAGNSDFLLSGGYNYVV
HHCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEECCHHHHH
DAIDHITSKLHLIRSCRERELRIISSMGAANKLDPTKIRVADISKTSVCGLARVVRKQLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
RQGIKSGVTVVYSTEEPREQAIADAGCRSNCICPNKEEQRFSCEHRRNILGSISFIPSIF
HHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLTMAGVVVNDLAKD
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]