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The map label for this gene is yabD [H]

Identifier: 78224427

GI number: 78224427

Start: 3642090

End: 3642848

Strand: Direct

Name: yabD [H]

Synonym: Gmet_3236

Alternate gene names: 78224427

Gene position: 3642090-3642848 (Clockwise)

Preceding gene: 78224426

Following gene: 78224428

Centisome position: 91.11

GC content: 67.33

Gene sequence:

>759_bases
ATGCTCACCGACACCCACTGCCACCTGGATGACCCGACCCTCAGCTCGCGCCTCGGCGAGGTCATGGCCGCCGCGCGACA
GGCCGGGGTCGGACGGATCATCGTTCCGGGGATCGCTCCGGGTGGATGGGAGCGGATCGCCTCCCTGGCACGGGAGCAGG
AGGGAATCTTTCCCGCCTTCGGCATCTATCCCCAGACGGCGGGCCAGGCCGACGACGGCGCCCTGGCGCGGCTCGCCACC
CTCAGTGGCACAGCCGTTGCCGTGGGGGAGATCGGGCTCGACCATCTGCTTTCCACCGTTCCCCACGAAACCCAGGAGGC
GGCGTTCCGGAAGCAACTCCGGATCGCGGTGGTAGCGGGGCTTCCGGTCATCATTCATTGCCGCCGGGCCTTCGAGCCCC
TTCTCCGCATCCTCAGAGAGGAAAGTGTCTCCCGGGTTGGCGGGGTCATGCACGCCTTCTCCGGTAGCGTGGAGATTGCC
CGGGAATGCATCAGGCTCGGCCTCTTCATCTCCGTCGCGGGGACCGTTACCTACCGTAACGCCGTGAGACCCGTGACCGT
AGCCCGGGAGATCCCCCTGGAACACCTCCTCATCGAGACCGACGCCCCCGACATGACCCCCGAGCCTTTCCGCGGCGCAC
CCAACGAGCCGGCATTTCTCGCGGTGACGGCACACCGCCTGGCGGAGCTGAAGGGGGTGACGCCGGAGGAGGTGGCCCGG
GCTACGAGCGAGAATGCTGTGCGGCTCTTTCGTTTATAA

Upstream 100 bases:

>100_bases
GCTGCCATGACGGACGCCCTCGTCGACTTTTTTTCACGGTCGAAGTAGATACGCCTCTCCTTCACCCCTCGCCCCTGCAA
CCGGAGTGTGGAGCGCCCCG

Downstream 100 bases:

>100_bases
TTCTTTGCAAAATCAATGCAATAACACGGGGCAACGGAGCACACGGAGAAAAGCAAGATCCGATTTGTTCATCGCTATGA
TATTCAGGAGATTCCGGTTC

Product: TatD-related deoxyribonuclease:amidohydrolase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLTDTHCHLDDPTLSSRLGEVMAAARQAGVGRIIVPGIAPGGWERIASLAREQEGIFPAFGIYPQTAGQADDGALARLAT
LSGTAVAVGEIGLDHLLSTVPHETQEAAFRKQLRIAVVAGLPVIIHCRRAFEPLLRILREESVSRVGGVMHAFSGSVEIA
RECIRLGLFISVAGTVTYRNAVRPVTVAREIPLEHLLIETDAPDMTPEPFRGAPNEPAFLAVTAHRLAELKGVTPEEVAR
ATSENAVRLFRL

Sequences:

>Translated_252_residues
MLTDTHCHLDDPTLSSRLGEVMAAARQAGVGRIIVPGIAPGGWERIASLAREQEGIFPAFGIYPQTAGQADDGALARLAT
LSGTAVAVGEIGLDHLLSTVPHETQEAAFRKQLRIAVVAGLPVIIHCRRAFEPLLRILREESVSRVGGVMHAFSGSVEIA
RECIRLGLFISVAGTVTYRNAVRPVTVAREIPLEHLLIETDAPDMTPEPFRGAPNEPAFLAVTAHRLAELKGVTPEEVAR
ATSENAVRLFRL
>Mature_252_residues
MLTDTHCHLDDPTLSSRLGEVMAAARQAGVGRIIVPGIAPGGWERIASLAREQEGIFPAFGIYPQTAGQADDGALARLAT
LSGTAVAVGEIGLDHLLSTVPHETQEAAFRKQLRIAVVAGLPVIIHCRRAFEPLLRILREESVSRVGGVMHAFSGSVEIA
RECIRLGLFISVAGTVTYRNAVRPVTVAREIPLEHLLIETDAPDMTPEPFRGAPNEPAFLAVTAHRLAELKGVTPEEVAR
ATSENAVRLFRL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=28.7878787878788, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=28.7878787878788, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=28.6245353159851, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=29.1338582677165, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI14042943, Length=205, Percent_Identity=32.6829268292683, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI225903439, Length=164, Percent_Identity=35.3658536585366, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=26.8722466960352, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI225903424, Length=218, Percent_Identity=30.2752293577982, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=36.71875, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=37.2549019607843, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=32.5581395348837, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=31.4285714285714, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=28.3582089552239, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17565396, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543026, Length=180, Percent_Identity=31.1111111111111, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=28.2229965156794, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24586117, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221330018, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 27057; Mature: 27057

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDTHCHLDDPTLSSRLGEVMAAARQAGVGRIIVPGIAPGGWERIASLAREQEGIFPAF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
GIYPQTAGQADDGALARLATLSGTAVAVGEIGLDHLLSTVPHETQEAAFRKQLRIAVVAG
CCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
LPVIIHCRRAFEPLLRILREESVSRVGGVMHAFSGSVEIARECIRLGLFISVAGTVTYRN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
AVRPVTVAREIPLEHLLIETDAPDMTPEPFRGAPNEPAFLAVTAHRLAELKGVTPEEVAR
CCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
ATSENAVRLFRL
HHCCCCEEEECC
>Mature Secondary Structure
MLTDTHCHLDDPTLSSRLGEVMAAARQAGVGRIIVPGIAPGGWERIASLAREQEGIFPAF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
GIYPQTAGQADDGALARLATLSGTAVAVGEIGLDHLLSTVPHETQEAAFRKQLRIAVVAG
CCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
LPVIIHCRRAFEPLLRILREESVSRVGGVMHAFSGSVEIARECIRLGLFISVAGTVTYRN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
AVRPVTVAREIPLEHLLIETDAPDMTPEPFRGAPNEPAFLAVTAHRLAELKGVTPEEVAR
CCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
ATSENAVRLFRL
HHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]