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The map label for this gene is actP [H]

Identifier: 78224224

GI number: 78224224

Start: 3416291

End: 3417820

Strand: Reverse

Name: actP [H]

Synonym: Gmet_3031

Alternate gene names: 78224224

Gene position: 3417820-3416291 (Counterclockwise)

Preceding gene: 78224225

Following gene: 78224223

Centisome position: 85.5

GC content: 64.31

Gene sequence:

>1530_bases
ATGACTGACGCGGGGCCCAATCTCATACCCCTCATCATTGTCACCCTTGCCCTTGCCTCCTTCATCGTGGCGGGGCTCCG
CGCCCGGGCCCGGAGCGCCAGCGATTACGGCATCGGTGGCCGCTACATCGGCCGGATCGGCGGCGGGGCCGCCATCGCCA
GCAACTGGATGAGCGCTGCGAGCCTCCTCGGCATGGGGGGACTCCTCTACCTCCACGGGTATTACGCCCTGGCCTACGTG
ATCGGCTGGACCGGCGGGTACGTACTCCTTCTGGTCCTCATGGCGGGACAGATCCGGCGTTTCGGCAAGTACACGGCGCC
GGACTTCGTGGGGGACCGTTACGCGTCGCCCATGGCAGGTCTCATCTCCGCCGGCATCTCCATCACCATCTCGATCATCT
ACTGCACGGCCCAGTTCAAGGGGATCGGGATGCTCTTCGGCTGGCTCTTCGGCACCGGCTATCGCAACGGCGTGATCCTG
GGAGCCGTCGTGGTGGTTGGGTACGTGATCATCTCGGGGGTGCTGGGTGTGGCCCGCAACCAGCAACTCCAGTACACGCT
TCTCATTGTCTCCTTCATTCTCCCCCTCATGGTGCTGGCGTACAAGCTCGGCTACTTCTGGGTTCTCCCCCAGTTCGGCT
ATGGGGTGGCCATCCAGGACCTGAAACGGGAGTTCGGCATCAACTTCGCTGCCCCCTTTGCCTCGGGTTCCCTCTTTCAG
TGGATATCCCTCTGCTTCACCCTCATGGTGGGGACCGCAGGGCTCCCCCACGTGCTGTCGCGCTTCTACGTGGTCCCCAA
CATCCGGGACGCCCGGTGGAGCCTCGTGTGGGGGCTCTTCTTCATCGCCCTCATCTACTGGTCGGCTCCGGCCTACGCCG
TCTTTGCCCGGCTTCTGGAGGCCCGAGCCGGAATGACCCTTCCGCCTGCCGCGGCCGAGAAAATGGCCGACCTTATCGTT
ATAAGGACAGCGGTCATGGGGGGGCTTCCCCCGTGGATGATCGGGATTCTCGCCGCCGGGGCCGTGAGCGCCGCCTTTTT
CACCGTGGCCGGGCTCCTCATCACCGGCGCCTCCTCTTTTTCCCACGACATCTACTACCGTTTCATCAACCCCCGGGCGT
CGGAGACCACCAAGATGGCCCTCTCCAAAGCGGCGGTGGTGGCCCTGGCCGTGGTGGTGCTGGTGATCGCCATGGACCCG
CCGGGACTCATCGCCGAGATTACCGCCGTGGCCTTTGCCCTGGCCGGCAATACCATTTTCCCCGCGTTCCTCCTGGGTAT
CTGGTGGGGGCGGGCCAACCGCCACGGGGTTATCGCAGGGATGCTGACCGGGGTCGTCATTACCTTTTCGACTCCCCTAT
TCGGCCGTTTTCTGCCGGTAGTGGCGGATATTTTCCCCCTTACCTCGTCGGCCTTTTTCGGCGCGCCGGCCGTTATCGCC
GTAATGGTAGCGGTGTCGCTCCTGACCCCTCCGCCCCCTGAAGAGGTCCGGCGGTTCCTGGCCGAGCAGGTTCACGGCCA
CATGGACTGA

Upstream 100 bases:

>100_bases
GCCCAGTTTCTCCCCCTCTGGTTCATCATTCTCTGCATCCTCTTCAATATTTACATCGACCGGCACACGGAGCAGCACAG
CAGAAGGAAGGATCGAAGCC

Downstream 100 bases:

>100_bases
CTATGACGGTAAAGGAGCTGTGACATGGCGCTGTTACTAGGTGCGAGGGGGGAGGATATCCTTACCCGGCGCGGGACCGC
CGAGTTCATCGAGCAGGTGC

Product: Na+/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTDAGPNLIPLIIVTLALASFIVAGLRARARSASDYGIGGRYIGRIGGGAAIASNWMSAASLLGMGGLLYLHGYYALAYV
IGWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPMAGLISAGISITISIIYCTAQFKGIGMLFGWLFGTGYRNGVIL
GAVVVVGYVIISGVLGVARNQQLQYTLLIVSFILPLMVLAYKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASGSLFQ
WISLCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARAGMTLPPAAAEKMADLIV
IRTAVMGGLPPWMIGILAAGAVSAAFFTVAGLLITGASSFSHDIYYRFINPRASETTKMALSKAAVVALAVVVLVIAMDP
PGLIAEITAVAFALAGNTIFPAFLLGIWWGRANRHGVIAGMLTGVVITFSTPLFGRFLPVVADIFPLTSSAFFGAPAVIA
VMVAVSLLTPPPPEEVRRFLAEQVHGHMD

Sequences:

>Translated_509_residues
MTDAGPNLIPLIIVTLALASFIVAGLRARARSASDYGIGGRYIGRIGGGAAIASNWMSAASLLGMGGLLYLHGYYALAYV
IGWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPMAGLISAGISITISIIYCTAQFKGIGMLFGWLFGTGYRNGVIL
GAVVVVGYVIISGVLGVARNQQLQYTLLIVSFILPLMVLAYKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASGSLFQ
WISLCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARAGMTLPPAAAEKMADLIV
IRTAVMGGLPPWMIGILAAGAVSAAFFTVAGLLITGASSFSHDIYYRFINPRASETTKMALSKAAVVALAVVVLVIAMDP
PGLIAEITAVAFALAGNTIFPAFLLGIWWGRANRHGVIAGMLTGVVITFSTPLFGRFLPVVADIFPLTSSAFFGAPAVIA
VMVAVSLLTPPPPEEVRRFLAEQVHGHMD
>Mature_508_residues
TDAGPNLIPLIIVTLALASFIVAGLRARARSASDYGIGGRYIGRIGGGAAIASNWMSAASLLGMGGLLYLHGYYALAYVI
GWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPMAGLISAGISITISIIYCTAQFKGIGMLFGWLFGTGYRNGVILG
AVVVVGYVIISGVLGVARNQQLQYTLLIVSFILPLMVLAYKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASGSLFQW
ISLCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLEARAGMTLPPAAAEKMADLIVI
RTAVMGGLPPWMIGILAAGAVSAAFFTVAGLLITGASSFSHDIYYRFINPRASETTKMALSKAAVVALAVVVLVIAMDPP
GLIAEITAVAFALAGNTIFPAFLLGIWWGRANRHGVIAGMLTGVVITFSTPLFGRFLPVVADIFPLTSSAFFGAPAVIAV
MVAVSLLTPPPPEEVRRFLAEQVHGHMD

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=492, Percent_Identity=23.9837398373984, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1790503, Length=469, Percent_Identity=30.7036247334755, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1787251, Length=496, Percent_Identity=25.8064516129032, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082237, Length=455, Percent_Identity=21.3186813186813, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54262; Mature: 54131

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAGPNLIPLIIVTLALASFIVAGLRARARSASDYGIGGRYIGRIGGGAAIASNWMSAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
SLLGMGGLLYLHGYYALAYVIGWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPMAG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHH
LISAGISITISIIYCTAQFKGIGMLFGWLFGTGYRNGVILGAVVVVGYVIISGVLGVARN
HHHCCCEEEEEEEEEECHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QQLQYTLLIVSFILPLMVLAYKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASGSLFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCEECCCCCCCHHH
WISLCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLE
HHHHHHHHHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAGMTLPPAAAEKMADLIVIRTAVMGGLPPWMIGILAAGAVSAAFFTVAGLLITGASSF
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SHDIYYRFINPRASETTKMALSKAAVVALAVVVLVIAMDPPGLIAEITAVAFALAGNTIF
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
PAFLLGIWWGRANRHGVIAGMLTGVVITFSTPLFGRFLPVVADIFPLTSSAFFGAPAVIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHH
VMVAVSLLTPPPPEEVRRFLAEQVHGHMD
HHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDAGPNLIPLIIVTLALASFIVAGLRARARSASDYGIGGRYIGRIGGGAAIASNWMSAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
SLLGMGGLLYLHGYYALAYVIGWTGGYVLLLVLMAGQIRRFGKYTAPDFVGDRYASPMAG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHH
LISAGISITISIIYCTAQFKGIGMLFGWLFGTGYRNGVILGAVVVVGYVIISGVLGVARN
HHHCCCEEEEEEEEEECHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QQLQYTLLIVSFILPLMVLAYKLGYFWVLPQFGYGVAIQDLKREFGINFAAPFASGSLFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCEECCCCCCCHHH
WISLCFTLMVGTAGLPHVLSRFYVVPNIRDARWSLVWGLFFIALIYWSAPAYAVFARLLE
HHHHHHHHHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAGMTLPPAAAEKMADLIVIRTAVMGGLPPWMIGILAAGAVSAAFFTVAGLLITGASSF
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SHDIYYRFINPRASETTKMALSKAAVVALAVVVLVIAMDPPGLIAEITAVAFALAGNTIF
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
PAFLLGIWWGRANRHGVIAGMLTGVVITFSTPLFGRFLPVVADIFPLTSSAFFGAPAVIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHH
VMVAVSLLTPPPPEEVRRFLAEQVHGHMD
HHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA