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The map label for this gene is thiG [H]

Identifier: 78224129

GI number: 78224129

Start: 3319693

End: 3319989

Strand: Direct

Name: thiG [H]

Synonym: Gmet_2933

Alternate gene names: 78224129

Gene position: 3319693-3319989 (Clockwise)

Preceding gene: 78224128

Following gene: 78224130

Centisome position: 83.05

GC content: 57.58

Gene sequence:

>297_bases
ATGGTCTATTCCACGACCACGGGCCGCTTCTGCGGCCTTTTTTGTTTACGCGACCAGATGCCGGTTTCGACGAACCGGCA
CCCATACTCGGAGAACACAATGGAAATCATCGTCAACGGCGAAGCACGGGCTGCCACCCCCATGTCGATGCTTGAGCTTC
TTCGCTCCCTCGACATCGACCCCCGCCGGGTGGCGGTAGAACTGAACCACGACATTCTTCCCAAGGGTGAATACGAATCC
ACCATCCTCAACGACGGAGACCGGATCGAGATCGTCCACTTTGTGGGCGGGGGATAA

Upstream 100 bases:

>100_bases
CCAACTCGCTAGGGGAGTTTCGACTGAGAGTCCGACGCGCTGCTACGGACAACCCTTTGAACCTGATCCGGATAATGCCG
GCGTAGGGAAGCGTTCCACC

Downstream 100 bases:

>100_bases
CAAAGGAGACTACCCATGTCCACTACGAACGACAAGCTGATCATCGCCGGCCGGGAATTCAGCTCCCGCCTCATGGTCGG
AACCGGCAAATACGCCAGTA

Product: ThiS, thiamine-biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MVYSTTTGRFCGLFCLRDQMPVSTNRHPYSENTMEIIVNGEARAATPMSMLELLRSLDIDPRRVAVELNHDILPKGEYES
TILNDGDRIEIVHFVGGG

Sequences:

>Translated_98_residues
MVYSTTTGRFCGLFCLRDQMPVSTNRHPYSENTMEIIVNGEARAATPMSMLELLRSLDIDPRRVAVELNHDILPKGEYES
TILNDGDRIEIVHFVGGG
>Mature_98_residues
MVYSTTTGRFCGLFCLRDQMPVSTNRHPYSENTMEIIVNGEARAATPMSMLELLRSLDIDPRRVAVELNHDILPKGEYES
TILNDGDRIEIVHFVGGG

Specific function: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S [H]

COG id: COG2104

COG function: function code H; Sulfur transfer protein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012675
- InterPro:   IPR016155
- InterPro:   IPR010035
- InterPro:   IPR008867
- InterPro:   IPR003749 [H]

Pfam domain/function: PF05690 ThiG; PF02597 ThiS [H]

EC number: NA

Molecular weight: Translated: 10984; Mature: 10984

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYSTTTGRFCGLFCLRDQMPVSTNRHPYSENTMEIIVNGEARAATPMSMLELLRSLDID
CEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
PRRVAVELNHDILPKGEYESTILNDGDRIEIVHFVGGG
CCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEEECCC
>Mature Secondary Structure
MVYSTTTGRFCGLFCLRDQMPVSTNRHPYSENTMEIIVNGEARAATPMSMLELLRSLDID
CEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
PRRVAVELNHDILPKGEYESTILNDGDRIEIVHFVGGG
CCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA