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The map label for this gene is cysH [H]

Identifier: 78224054

GI number: 78224054

Start: 3237331

End: 3238038

Strand: Direct

Name: cysH [H]

Synonym: Gmet_2858

Alternate gene names: 78224054

Gene position: 3237331-3238038 (Clockwise)

Preceding gene: 78224053

Following gene: 78224055

Centisome position: 80.99

GC content: 62.43

Gene sequence:

>708_bases
ATGACTGCAACCATTCAGAAAACAATCCCCCAACTTCCCCAGGACGCCACTCCACAGGACATCCTCAGGGCCGGAGTGTC
GGCGACCGAGGGTTCTGTCAAGCTCGCCTGCTCCTTCTCTGTGGAGGACGTCATCATCATCGACATGGCAAAGGAACTGG
GGTGCCCGATTGGGATATTCGCCCTCGACACGGGGCGCCTCCACGAGGAGACCTACGAGGTGGCAGACGCCATCACGGAG
CGCTACCGGATCCCGATAGACTGGTATTTCCCGCGGCACGAGACGGTGGAAAAGCTCGAACGCGACAAGGGGCTTTTCTC
TTTCCGTGAATCCCTGGATAACCGCCATGAGTGCTGCCACATCCGCAAGGTGGAGCCACTTGGCCGGGCGCTCAAGGGGC
TTGCCGGCTGGATCACCGGGCTCCGCCGCGAACAGAGCGTCACGCGGACCGGCCTCGCTCCCATCGAGAGCGACGAAGCA
AACGGCGGCATCCTGAAAATCAACCCGCTCCTGGAGTGGAGTGAGGAACAGGTCTGGGAGTACGCCGAAAAGCGCCGGGT
ACCGGTGAACCGTCTCCATAAACAGGGATACCCTTCGATCGGCTGCGCTCCCTGCACCCGCCCCGTGGCCCCGGGCGAGC
ATCCCCGAGCCGGACGATGGTGGTGGGAGAATCCGGAGCATAAAGAGTGCGGGTTGCACCGGCACTGA

Upstream 100 bases:

>100_bases
GGCTGCGGCAATCTTCATCTGGCCCCTGATTGGCCTGAACATCTGAACACCCTTTGCCCGGAGCGCTCACGCACTACGGA
CACGACCCAAAGGATCCAAC

Downstream 100 bases:

>100_bases
TGGAAGGCACAATCGTCTACGAGGATAACGACATGAGAACCACGCTGACCCACCTGCAGCAGCTCGAAGCAGAAAGCATC
CACATCATCCGAGAGGTGGT

Product: phosphoadenylylsulfate reductase (thioredoxin)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTATIQKTIPQLPQDATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKELGCPIGIFALDTGRLHEETYEVADAITE
RYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCHIRKVEPLGRALKGLAGWITGLRREQSVTRTGLAPIESDEA
NGGILKINPLLEWSEEQVWEYAEKRRVPVNRLHKQGYPSIGCAPCTRPVAPGEHPRAGRWWWENPEHKECGLHRH

Sequences:

>Translated_235_residues
MTATIQKTIPQLPQDATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKELGCPIGIFALDTGRLHEETYEVADAITE
RYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCHIRKVEPLGRALKGLAGWITGLRREQSVTRTGLAPIESDEA
NGGILKINPLLEWSEEQVWEYAEKRRVPVNRLHKQGYPSIGCAPCTRPVAPGEHPRAGRWWWENPEHKECGLHRH
>Mature_234_residues
TATIQKTIPQLPQDATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKELGCPIGIFALDTGRLHEETYEVADAITER
YRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCHIRKVEPLGRALKGLAGWITGLRREQSVTRTGLAPIESDEAN
GGILKINPLLEWSEEQVWEYAEKRRVPVNRLHKQGYPSIGCAPCTRPVAPGEHPRAGRWWWENPEHKECGLHRH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=205, Percent_Identity=28.780487804878, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325425, Length=239, Percent_Identity=33.8912133891213, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26710; Mature: 26578

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATIQKTIPQLPQDATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKELGCPIGIF
CCCCHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCCEEEE
ALDTGRLHEETYEVADAITERYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCH
EECCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHCCHHHHEH
IRKVEPLGRALKGLAGWITGLRREQSVTRTGLAPIESDEANGGILKINPLLEWSEEQVWE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
YAEKRRVPVNRLHKQGYPSIGCAPCTRPVAPGEHPRAGRWWWENPEHKECGLHRH
HHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TATIQKTIPQLPQDATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKELGCPIGIF
CCCHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCCEEEE
ALDTGRLHEETYEVADAITERYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCH
EECCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHCCHHHHEH
IRKVEPLGRALKGLAGWITGLRREQSVTRTGLAPIESDEANGGILKINPLLEWSEEQVWE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
YAEKRRVPVNRLHKQGYPSIGCAPCTRPVAPGEHPRAGRWWWENPEHKECGLHRH
HHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA