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The map label for this gene is int [H]

Identifier: 78223999

GI number: 78223999

Start: 3165949

End: 3167298

Strand: Direct

Name: int [H]

Synonym: Gmet_2803

Alternate gene names: 78223999

Gene position: 3165949-3167298 (Clockwise)

Preceding gene: 78223986

Following gene: 78224004

Centisome position: 79.2

GC content: 56.74

Gene sequence:

>1350_bases
ATGATTCAAGTCCCGCGTGATACGATGGCCCGGTTCGAGGCTGTTCTCAAGAGGAAGGGAATGCCGCTCGGCAGCTTTGG
GGATTACAGGAAATGGCTGCGCTATTATTTCGATTTTTCGTCAAAATATCCTGAATCTCGAGGCAGGTCTGAACAGGTTC
GCAAGTTTCTGGAAAAGTTGCGTGACAAGAATCAGTCCGAGGCACAACGAAGACAGGCGGCCCATGCGATCTCACTGTAT
TTTGAGATGCAGCGGGAGGAGGAGCCGCCGCAGTGTAATGAAATTCCATCCTCTCCTCCCCAACGATCAACCTGTATTGT
TCCACAGTCTCCTCCCCGTCAACGCAAATCATATTACTCCGAGGCCGGCTATCAGGAAAAATCCGATTCCCCCGAATGGG
ACGAGGTGCTGGGCAAACTGGCGGCCGAGATCAAGGTGCGCCACTATTCCCGCAAGACCCTGAAAACCTACGCCTTATGG
TCGCGAAAATTTCAGCGGTTCCTGAAGAACAAGCCTCCGCAAGAGCTTTCAACCGCCGATGTGAAGGAGTACCTGACCTA
CCTGGCGGTAAAGTGCAATGTCGCGGCTTCGACCCAGAACCAGGCGTTCAATTCGCTGCTATTCCTCTTCCGCCACGGTT
TGAAGCGGGAATTCGGCGAACTGCGCGATGTGCCGCGGGCGAAGAAGTCCCTGTATGTGCCGGTGGTGCTCTCCCGCGAG
GAGATCGACGCCATTCTGAAGCATCTGTCCCATCCGTTCAGCCTGGTGGTGAACCTGCTCTTCGGCTGCGGCCTGAGGCT
GTTCGAGTGTCTGCAGTTGCGGGTGCGGGATTTCAATTTCGATGCCGTCGTCCTGACGGTGCATGGCAAGGGGAAAAAGG
ACCGGACCGTGCCGCTGCCGGAGGCGATCCTTCCGGAGCTGACGGCACAGATTGAACGGGTGAAGGCTTTACACGAAAAG
GATCTTGCAGCGGGATACGCGGGGGTGTTCCTCGACGACGCCGTGGAGAAGAAGTATCCCCATGCCCCGAAGGAGCTGAT
CCACCAGTGGTTCTTTCCGCAGCAGTCGTTGACGCTGGTGGAGGAAACCGGGGAACTGAGACGCTATCATCTCCACGAGT
CCCTGTTGCAGGAGGCTCTGTACGTGGCCGTGCGCAGGGCGAAGATACCCAAGCGGGTCACGGCCCACACCTTCCGGCAT
TCCTACGCGACCCACCTCTTGCAAGCCAATTACGATATCCGCACCATCCAGACCAAGCTGGGACACGCAAGCCTCAAAAC
AACCATGATCTATACCCACTGCGTGCCGGTCCGGACGGTGAAGGAGGCGAAAAGCCCGCTGGATTTCTAG

Upstream 100 bases:

>100_bases
CAAAGAGACTTTATGAGAACTTTCTATTTAACACCGTAACCCGCGCCGCGCTAAGTTTGCCACCGATCTGCTTGTATTTT
TCACTTTCTGGGGATGGCTC

Downstream 100 bases:

>100_bases
CTCACACCCTTCCCAGATCGAGCCACTTTTCCGCCACCGGCGGCCGGTAGGCGCGGAAGCGCTCTAGCAGCGCATCGGGG
CGTTCTTCCACGACGATCAT

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MIQVPRDTMARFEAVLKRKGMPLGSFGDYRKWLRYYFDFSSKYPESRGRSEQVRKFLEKLRDKNQSEAQRRQAAHAISLY
FEMQREEEPPQCNEIPSSPPQRSTCIVPQSPPRQRKSYYSEAGYQEKSDSPEWDEVLGKLAAEIKVRHYSRKTLKTYALW
SRKFQRFLKNKPPQELSTADVKEYLTYLAVKCNVAASTQNQAFNSLLFLFRHGLKREFGELRDVPRAKKSLYVPVVLSRE
EIDAILKHLSHPFSLVVNLLFGCGLRLFECLQLRVRDFNFDAVVLTVHGKGKKDRTVPLPEAILPELTAQIERVKALHEK
DLAAGYAGVFLDDAVEKKYPHAPKELIHQWFFPQQSLTLVEETGELRRYHLHESLLQEALYVAVRRAKIPKRVTAHTFRH
SYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEAKSPLDF

Sequences:

>Translated_449_residues
MIQVPRDTMARFEAVLKRKGMPLGSFGDYRKWLRYYFDFSSKYPESRGRSEQVRKFLEKLRDKNQSEAQRRQAAHAISLY
FEMQREEEPPQCNEIPSSPPQRSTCIVPQSPPRQRKSYYSEAGYQEKSDSPEWDEVLGKLAAEIKVRHYSRKTLKTYALW
SRKFQRFLKNKPPQELSTADVKEYLTYLAVKCNVAASTQNQAFNSLLFLFRHGLKREFGELRDVPRAKKSLYVPVVLSRE
EIDAILKHLSHPFSLVVNLLFGCGLRLFECLQLRVRDFNFDAVVLTVHGKGKKDRTVPLPEAILPELTAQIERVKALHEK
DLAAGYAGVFLDDAVEKKYPHAPKELIHQWFFPQQSLTLVEETGELRRYHLHESLLQEALYVAVRRAKIPKRVTAHTFRH
SYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEAKSPLDF
>Mature_449_residues
MIQVPRDTMARFEAVLKRKGMPLGSFGDYRKWLRYYFDFSSKYPESRGRSEQVRKFLEKLRDKNQSEAQRRQAAHAISLY
FEMQREEEPPQCNEIPSSPPQRSTCIVPQSPPRQRKSYYSEAGYQEKSDSPEWDEVLGKLAAEIKVRHYSRKTLKTYALW
SRKFQRFLKNKPPQELSTADVKEYLTYLAVKCNVAASTQNQAFNSLLFLFRHGLKREFGELRDVPRAKKSLYVPVVLSRE
EIDAILKHLSHPFSLVVNLLFGCGLRLFECLQLRVRDFNFDAVVLTVHGKGKKDRTVPLPEAILPELTAQIERVKALHEK
DLAAGYAGVFLDDAVEKKYPHAPKELIHQWFFPQQSLTLVEETGELRRYHLHESLLQEALYVAVRRAKIPKRVTAHTFRH
SYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEAKSPLDF

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 52167; Mature: 52167

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVPRDTMARFEAVLKRKGMPLGSFGDYRKWLRYYFDFSSKYPESRGRSEQVRKFLEKL
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RDKNQSEAQRRQAAHAISLYFEMQREEEPPQCNEIPSSPPQRSTCIVPQSPPRQRKSYYS
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHH
EAGYQEKSDSPEWDEVLGKLAAEIKVRHYSRKTLKTYALWSRKFQRFLKNKPPQELSTAD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VKEYLTYLAVKCNVAASTQNQAFNSLLFLFRHGLKREFGELRDVPRAKKSLYVPVVLSRE
HHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEEEECHH
EIDAILKHLSHPFSLVVNLLFGCGLRLFECLQLRVRDFNFDAVVLTVHGKGKKDRTVPLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
EAILPELTAQIERVKALHEKDLAAGYAGVFLDDAVEKKYPHAPKELIHQWFFPQQSLTLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
EETGELRRYHLHESLLQEALYVAVRRAKIPKRVTAHTFRHSYATHLLQANYDIRTIQTKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GHASLKTTMIYTHCVPVRTVKEAKSPLDF
CCHHHHHHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MIQVPRDTMARFEAVLKRKGMPLGSFGDYRKWLRYYFDFSSKYPESRGRSEQVRKFLEKL
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RDKNQSEAQRRQAAHAISLYFEMQREEEPPQCNEIPSSPPQRSTCIVPQSPPRQRKSYYS
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHH
EAGYQEKSDSPEWDEVLGKLAAEIKVRHYSRKTLKTYALWSRKFQRFLKNKPPQELSTAD
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VKEYLTYLAVKCNVAASTQNQAFNSLLFLFRHGLKREFGELRDVPRAKKSLYVPVVLSRE
HHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEEEECHH
EIDAILKHLSHPFSLVVNLLFGCGLRLFECLQLRVRDFNFDAVVLTVHGKGKKDRTVPLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
EAILPELTAQIERVKALHEKDLAAGYAGVFLDDAVEKKYPHAPKELIHQWFFPQQSLTLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
EETGELRRYHLHESLLQEALYVAVRRAKIPKRVTAHTFRHSYATHLLQANYDIRTIQTKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GHASLKTTMIYTHCVPVRTVKEAKSPLDF
CCHHHHHHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]