Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 78223986

GI number: 78223986

Start: 3153951

End: 3155342

Strand: Direct

Name: aphA [H]

Synonym: Gmet_2790

Alternate gene names: 78223986

Gene position: 3153951-3155342 (Clockwise)

Preceding gene: 78223985

Following gene: 78223999

Centisome position: 78.9

GC content: 61.28

Gene sequence:

>1392_bases
ATGACTCGAATCCTGATCGTCGATGACAACGAGCAGAACCTCTACATGCTGGAGGTTTTACTCTCCGCGCACGGTTTTCA
GGCACTCTCGGCGACAAACGGAGCCGAAGCCCTGGCACTGGCCCAGGCCTCCCCCCCCGATCTCATCATCAGCGACATCC
TCATGCCGGTCATGGATGGGTACGCATTCTGTCGCGAATGCAAGAAGACGGCCCAGCTGAATGATGTGCCGTTCATATTC
TACACCGCCACCTTCACCGAGGCAGAGGACGAGAAGCTCGCCCTGAGCCTCGGCGCCGACCGCTTTCTCCTCAAGCCTCA
GGAGCCGGATGAGATGATGCGGATTGTCCGCGAGCTGCTCGCCGTGCCGCGGCCCGGAACCGGCCGAGAGCCGTCGGAGA
AAGGTCAGGAGCAGGCTGAACACCTCCAGAAGTATGGCGAAGCGCTGTTCCGGAAGCTGGAAAAAAGGATGGCCGACCTG
AAGCAGGCCAACCGGGCGCTGGAACACGAGATCGAAGAGCGCAAAAAGGCCGAACTGGAACTGCAGCAAGTGAACCGGAC
CCTCGAAGAACGGGTCGCCGAGCGCACTGCCCTGCTGGCAGCAGCCAACGGGCAGTTGCAGGAGGAAGTCCAGCGCTCCA
GGCAGGCCCAGAACGAGATCGCCCTGCTGAACGACGTTCTGGTGAGGCGGACCGAATCGCTGGAAGGGCTGAACCGGGAA
CTGGAGGCTTTCAGCTCGGCGGTCACCCATGACCTCCAGGCGCCGCTTCGGAGCATCATCGGATACGCCGGCATCGTGCG
CGAGGAGTGCGAAAATGCGGTCGACGGGTCGGTGCTCGAATATATCGGCAGAATCGAGCGGAGCGTCAACAGGATGAACG
AGCTGATCGAGGCGCTGCGGGACCTGTCGCAGGCCAGCTCCGCGGCGTTGCATCCCGACACCGTCAACCTGAGCACCATC
GTCCGGGAGATCATCTCCGCCCTGCAGGAAGCGGACTCGGAGCGCCGCGTGACCTTTGTCATAGCCGACGGCGTGACCGC
GGAGGCGGACAGGCCGCTGATCACATCGGTCATCGACAACCTGCTCAACAACGCCTGGAAGTACAGCCGGCGGAATGAAA
CGGCGCGGATAGAATTCGGCGCCCTGGAGAAAGACCAGGAGCACGTCTATTTCGTCAGGGATAACGGCGCCGGTTTTGAC
ATGAAGTACGCTTCGAAGCTTTTTACCCCCTTCCAGCGCCTGCATCGGCAGGATGAATTCGAAGGGACGGGGGTCGGGCT
GGCAACCGTCCAGCGGATCATTCACCGCCACGGCGGCAGGATCTGGGCGGAAGCAAAAGTGGCTGAAGGGGCAACGTTCT
ATTTTACCCTCAGTCGGGCAATGCATGGTTAA

Upstream 100 bases:

>100_bases
CGGTTGCAGCGGCTATATCGAGAAGCCGATCAATCCCGACACCTTCATGCAGCAGGTCAAGGAGCACTTGCCGGCCTAAT
CTGTCCAGAGGAGAGAAGGC

Downstream 100 bases:

>100_bases
CTGGTTGCCCTCTCCCCCTCGGCGCCGGGCATTTCTTCCCGGCCTTCTGCTGCTCCCATCGCCATCGAAATTCCGGAGTT
CCATTCGTCGTTTCGCGCTC

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTRILIVDDNEQNLYMLEVLLSAHGFQALSATNGAEALALAQASPPDLIISDILMPVMDGYAFCRECKKTAQLNDVPFIF
YTATFTEAEDEKLALSLGADRFLLKPQEPDEMMRIVRELLAVPRPGTGREPSEKGQEQAEHLQKYGEALFRKLEKRMADL
KQANRALEHEIEERKKAELELQQVNRTLEERVAERTALLAAANGQLQEEVQRSRQAQNEIALLNDVLVRRTESLEGLNRE
LEAFSSAVTHDLQAPLRSIIGYAGIVREECENAVDGSVLEYIGRIERSVNRMNELIEALRDLSQASSAALHPDTVNLSTI
VREIISALQEADSERRVTFVIADGVTAEADRPLITSVIDNLLNNAWKYSRRNETARIEFGALEKDQEHVYFVRDNGAGFD
MKYASKLFTPFQRLHRQDEFEGTGVGLATVQRIIHRHGGRIWAEAKVAEGATFYFTLSRAMHG

Sequences:

>Translated_463_residues
MTRILIVDDNEQNLYMLEVLLSAHGFQALSATNGAEALALAQASPPDLIISDILMPVMDGYAFCRECKKTAQLNDVPFIF
YTATFTEAEDEKLALSLGADRFLLKPQEPDEMMRIVRELLAVPRPGTGREPSEKGQEQAEHLQKYGEALFRKLEKRMADL
KQANRALEHEIEERKKAELELQQVNRTLEERVAERTALLAAANGQLQEEVQRSRQAQNEIALLNDVLVRRTESLEGLNRE
LEAFSSAVTHDLQAPLRSIIGYAGIVREECENAVDGSVLEYIGRIERSVNRMNELIEALRDLSQASSAALHPDTVNLSTI
VREIISALQEADSERRVTFVIADGVTAEADRPLITSVIDNLLNNAWKYSRRNETARIEFGALEKDQEHVYFVRDNGAGFD
MKYASKLFTPFQRLHRQDEFEGTGVGLATVQRIIHRHGGRIWAEAKVAEGATFYFTLSRAMHG
>Mature_462_residues
TRILIVDDNEQNLYMLEVLLSAHGFQALSATNGAEALALAQASPPDLIISDILMPVMDGYAFCRECKKTAQLNDVPFIFY
TATFTEAEDEKLALSLGADRFLLKPQEPDEMMRIVRELLAVPRPGTGREPSEKGQEQAEHLQKYGEALFRKLEKRMADLK
QANRALEHEIEERKKAELELQQVNRTLEERVAERTALLAAANGQLQEEVQRSRQAQNEIALLNDVLVRRTESLEGLNREL
EAFSSAVTHDLQAPLRSIIGYAGIVREECENAVDGSVLEYIGRIERSVNRMNELIEALRDLSQASSAALHPDTVNLSTIV
REIISALQEADSERRVTFVIADGVTAEADRPLITSVIDNLLNNAWKYSRRNETARIEFGALEKDQEHVYFVRDNGAGFDM
KYASKLFTPFQRLHRQDEFEGTGVGLATVQRIIHRHGGRIWAEAKVAEGATFYFTLSRAMHG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=29.3023255813954, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788394, Length=173, Percent_Identity=31.2138728323699, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=24.0174672489083, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=25.8474576271186, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=28.6852589641434, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=28.5067873303167, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=24.0663900414938, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=36.6666666666667, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789809, Length=137, Percent_Identity=32.8467153284672, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=30.3317535545024, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=310, Percent_Identity=26.7741935483871, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=30.5084745762712, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788393, Length=209, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52080; Mature: 51948

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILIVDDNEQNLYMLEVLLSAHGFQALSATNGAEALALAQASPPDLIISDILMPVMDG
CCEEEEEECCCCCHHHHHHHHHHCCCHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHH
YAFCRECKKTAQLNDVPFIFYTATFTEAEDEKLALSLGADRFLLKPQEPDEMMRIVRELL
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHH
AVPRPGTGREPSEKGQEQAEHLQKYGEALFRKLEKRMADLKQANRALEHEIEERKKAELE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQVNRTLEERVAERTALLAAANGQLQEEVQRSRQAQNEIALLNDVLVRRTESLEGLNRE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAFSSAVTHDLQAPLRSIIGYAGIVREECENAVDGSVLEYIGRIERSVNRMNELIEALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DLSQASSAALHPDTVNLSTIVREIISALQEADSERRVTFVIADGVTAEADRPLITSVIDN
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
LLNNAWKYSRRNETARIEFGALEKDQEHVYFVRDNGAGFDMKYASKLFTPFQRLHRQDEF
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
EGTGVGLATVQRIIHRHGGRIWAEAKVAEGATFYFTLSRAMHG
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCC
>Mature Secondary Structure 
TRILIVDDNEQNLYMLEVLLSAHGFQALSATNGAEALALAQASPPDLIISDILMPVMDG
CEEEEEECCCCCHHHHHHHHHHCCCHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHH
YAFCRECKKTAQLNDVPFIFYTATFTEAEDEKLALSLGADRFLLKPQEPDEMMRIVRELL
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHH
AVPRPGTGREPSEKGQEQAEHLQKYGEALFRKLEKRMADLKQANRALEHEIEERKKAELE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQVNRTLEERVAERTALLAAANGQLQEEVQRSRQAQNEIALLNDVLVRRTESLEGLNRE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAFSSAVTHDLQAPLRSIIGYAGIVREECENAVDGSVLEYIGRIERSVNRMNELIEALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DLSQASSAALHPDTVNLSTIVREIISALQEADSERRVTFVIADGVTAEADRPLITSVIDN
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
LLNNAWKYSRRNETARIEFGALEKDQEHVYFVRDNGAGFDMKYASKLFTPFQRLHRQDEF
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
EGTGVGLATVQRIIHRHGGRIWAEAKVAEGATFYFTLSRAMHG
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]