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The map label for this gene is cpkA [H]

Identifier: 78223982

GI number: 78223982

Start: 3149546

End: 3150490

Strand: Reverse

Name: cpkA [H]

Synonym: Gmet_2786

Alternate gene names: 78223982

Gene position: 3150490-3149546 (Counterclockwise)

Preceding gene: 78223984

Following gene: 78223981

Centisome position: 78.81

GC content: 66.67

Gene sequence:

>945_bases
ATGACCCACACCGTGAACCGCCCCATCCTCCTGATCGCCCTCGGCGGCAATGCCCTGATCCGCCAGGGAGAGCAGGGGAC
CTGCGCGGAGCAGTTCGCCAACCTGAGGCGCCCCATGGAGCAGATCGCGCGCCTGGCGGACCGCTACCGGATCATCATCA
CCCACGGCAACGGTCCCCAGGTGGGAAACCTCCTGATGCAGCAGGAGAGCTGCCCGGAGGTGCCGGCCATGCCCCTGGAG
GTCCTGGTGGCCCAGACCCAGGGACAGATCGGCTACATGATCGAATCGAGCCTGGAAAGCGAGCTTCTGGCCCTCGGTGG
GGAAAAACGGTTTCTGGTGAGCCTCATCAGCTACGTGCAGGTGGCGGAGGATGATCCCGCATTCCGCACCCCCACCAAGC
CCATCGGTCCCTGCTACACGGCTGAGGAGGCGGCGCGGTTCCCGTGGCCCATGGCGGGCACCCCCAAGGGGTACCGGCGG
GTGGTGGCGTCGCCGGAACCCCTGGCCGTGGTTGAAAAGGAAGAGATACGGCGCCTCGTGGAGGTGGATTTCATCGTGGT
CTGCTGCGGCGGGGGCGGGATTCCTGTTACCAGGGAGGGGCGCGCCTTCCACGGCATCGATGCGGTGATCGACAAGGATC
TGGCAAGCGCGTGCCTTTGCCTAGAAGTGGGGGTGGATATTCTGGTCATCGCCACCGACGTGCCGGGGGTGGCCACCGGC
TTCGGCACCGCGGCCGAGGAGTTCCTGAAGCGCCTCGATGCGGACGAGGCAGGGCGATTGCTGGCGGCCGGCCAGTTCCC
TCCGGGCTCCATGGGGCCGAAGGTGGAGGCGGTCCTCCGCTTTGTCCGCGGCGGCGGGAAGAGGGGGGTCATCTGCCATC
TGGACGAGATCGAACAGGCTGTTGCGGGCACGGCAGGAACGGAAATCACTGGAGGCGGATCATGA

Upstream 100 bases:

>100_bases
CCCGAATCCCCCCTTGTCAATGTCGTCGCCTGCATCGGGGCCATCTCTGTGGTACCATTGCAGAGACTCTCATGAATTCA
CACCGGGGAGAGGACCCACC

Downstream 100 bases:

>100_bases
AGCGGAAACGGATCATCATCATGGGGGCAGCCGGGCGGGACTTTCACAACTTCAACTGCTCCTTCCGGGACAACCCCGTC
TTCCGGGTCGTGGCGTTCAC

Product: carbamate kinase

Products: NA

Alternate protein names: Carbamate kinase-like carbamoylphosphate synthase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTHTVNRPILLIALGGNALIRQGEQGTCAEQFANLRRPMEQIARLADRYRIIITHGNGPQVGNLLMQQESCPEVPAMPLE
VLVAQTQGQIGYMIESSLESELLALGGEKRFLVSLISYVQVAEDDPAFRTPTKPIGPCYTAEEAARFPWPMAGTPKGYRR
VVASPEPLAVVEKEEIRRLVEVDFIVVCCGGGGIPVTREGRAFHGIDAVIDKDLASACLCLEVGVDILVIATDVPGVATG
FGTAAEEFLKRLDADEAGRLLAAGQFPPGSMGPKVEAVLRFVRGGGKRGVICHLDEIEQAVAGTAGTEITGGGS

Sequences:

>Translated_314_residues
MTHTVNRPILLIALGGNALIRQGEQGTCAEQFANLRRPMEQIARLADRYRIIITHGNGPQVGNLLMQQESCPEVPAMPLE
VLVAQTQGQIGYMIESSLESELLALGGEKRFLVSLISYVQVAEDDPAFRTPTKPIGPCYTAEEAARFPWPMAGTPKGYRR
VVASPEPLAVVEKEEIRRLVEVDFIVVCCGGGGIPVTREGRAFHGIDAVIDKDLASACLCLEVGVDILVIATDVPGVATG
FGTAAEEFLKRLDADEAGRLLAAGQFPPGSMGPKVEAVLRFVRGGGKRGVICHLDEIEQAVAGTAGTEITGGGS
>Mature_313_residues
THTVNRPILLIALGGNALIRQGEQGTCAEQFANLRRPMEQIARLADRYRIIITHGNGPQVGNLLMQQESCPEVPAMPLEV
LVAQTQGQIGYMIESSLESELLALGGEKRFLVSLISYVQVAEDDPAFRTPTKPIGPCYTAEEAARFPWPMAGTPKGYRRV
VASPEPLAVVEKEEIRRLVEVDFIVVCCGGGGIPVTREGRAFHGIDAVIDKDLASACLCLEVGVDILVIATDVPGVATGF
GTAAEEFLKRLDADEAGRLLAAGQFPPGSMGPKVEAVLRFVRGGGKRGVICHLDEIEQAVAGTAGTEITGGGS

Specific function: Arginine degradation via arginine deiminase; third step. [C]

COG id: COG0549

COG function: function code E; Carbamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786732, Length=305, Percent_Identity=42.6229508196721, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1789238, Length=310, Percent_Identity=40.3225806451613, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1786516, Length=314, Percent_Identity=39.4904458598726, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR003964
- InterPro:   IPR023000 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.2 [H]

Molecular weight: Translated: 33401; Mature: 33270

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTVNRPILLIALGGNALIRQGEQGTCAEQFANLRRPMEQIARLADRYRIIITHGNGPQ
CCCCCCCCEEEEEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
VGNLLMQQESCPEVPAMPLEVLVAQTQGQIGYMIESSLESELLALGGEKRFLVSLISYVQ
HHHHHHHHCCCCCCCCCCHHHHEECCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAEDDPAFRTPTKPIGPCYTAEEAARFPWPMAGTPKGYRRVVASPEPLAVVEKEEIRRLV
HCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEECHHHHHHHH
EVDFIVVCCGGGGIPVTREGRAFHGIDAVIDKDLASACLCLEVGVDILVIATDVPGVATG
HEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHC
FGTAAEEFLKRLDADEAGRLLAAGQFPPGSMGPKVEAVLRFVRGGGKRGVICHLDEIEQA
CCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHH
VAGTAGTEITGGGS
HCCCCCCCCCCCCC
>Mature Secondary Structure 
THTVNRPILLIALGGNALIRQGEQGTCAEQFANLRRPMEQIARLADRYRIIITHGNGPQ
CCCCCCCEEEEEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
VGNLLMQQESCPEVPAMPLEVLVAQTQGQIGYMIESSLESELLALGGEKRFLVSLISYVQ
HHHHHHHHCCCCCCCCCCHHHHEECCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAEDDPAFRTPTKPIGPCYTAEEAARFPWPMAGTPKGYRRVVASPEPLAVVEKEEIRRLV
HCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEECHHHHHHHH
EVDFIVVCCGGGGIPVTREGRAFHGIDAVIDKDLASACLCLEVGVDILVIATDVPGVATG
HEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHC
FGTAAEEFLKRLDADEAGRLLAAGQFPPGSMGPKVEAVLRFVRGGGKRGVICHLDEIEQA
CCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHH
VAGTAGTEITGGGS
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11523892; 12622808 [H]