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The map label for this gene is cph1 [H]

Identifier: 78223933

GI number: 78223933

Start: 3093975

End: 3095546

Strand: Direct

Name: cph1 [H]

Synonym: Gmet_2737

Alternate gene names: 78223933

Gene position: 3093975-3095546 (Clockwise)

Preceding gene: 78223932

Following gene: 78223934

Centisome position: 77.4

GC content: 65.71

Gene sequence:

>1572_bases
ATGGATAAGAACTCCCCCTGTGATTCTTCCCAACCGGCGAACCCCACCCCGCCACGGGACGTCCGCGGGAGCTTTCGCGC
CAAACTCTTCTCGGCGACAGCCGCCGGCATCGTTATCCTCTCGGCTGTTTCCATCGTCTTCTTCCTCACCAACCAGCACG
CCATACTCCACGAGAATCTTGTCACCGAGGGTCAGCTCCTGACCCGCCTCCTTGCCCATAACGCCCGTCTGGGGCTCTTT
GCCGCCAACCGCGACCAGCTCGCCGACCTGGCCGATGGGGTGATACGGACCCCCGACGTGCTGGAGGTAACCATCGTCGA
CCGGGATGGCCGGACCCTGGCCCGCGCGGCGCGGCAATCGGTGAGCGATGGCGGGAGCAGCGCCGCCCTGACGCAGGAGT
TTTCGGAGCCGGTCTTCGCGCTCCAGGGCAAGGGGAACGATGATGACCTCTACTTCTCGCCGGCGCAACAGCCGCCCCAG
GCCGGCCAGCGCCTCGGGACGGTGCGGGTCGTGATGGATGAAGAGAAGGTCCATGCCCACGTCCGCCGCCTCACCGCCAC
GGCGGTCATTGGGGCGCTGGCGTTTCTGGCCGTTGGAATGGGGCTGGTCTACTTGATCATCCGCGGCATCACCCGTCCCC
TCACCCACCTGTCGGATGAGGTCAGGGCCATCGAAAGGGGAGAGACGAACGTACTCCTCCCGGTGGAATCGGAGGACGAG
ATCGGCGAGCTCACCGCATCCTACAACCGGATGGTGAACGCCCTCAGGCAGCGGCGGGAGGAACGGGACGAGGCGGAGAG
GCAGTTGCGGGAGCTGAATGCCCGTCTGGAGGATAAGGTCATTGACCGGACCGCCCAGCTGGAGGCGGTGAACCGGGAAC
TGGAGTCGTTCAGCTATTCGGCCGCCCATGACCTGCGGGCGCCGCTCTTGCGCCTGAACGGCCTCTGCAAGGCCCTGAAG
GAGGACTGCGGCGAGCGGCTCGACGAGGAGGCCCGCGCGTATATCCGGCGCATCGCCACGGTGGGAAGGCAGATGGAGCG
GGTGATCTCGACCATGTCGACCCTGTTCAACGTGCAGCGGCGGGGAATGACCTGCCGGGAGATGGACCTGGGCGCCATGG
TGCGGGCGATCGTCGCGACGCTGCGGCAGGCCGATCCCCTGCGGGAGGTGGCGCTGACGGTGGGGCCAGAAGTGACGGCC
CACGGCGACACGGAACTCATCTGGACGGCCCTGGAGAACATGGTGGGGAACGCCTGGAAGTTCACGTCACGCACCCCCGA
TGCCCGCATCGAGTTCGGCAGCATCGAGCGGGACGGGGAGAAGGTCTTCCTCCTGAAAGACAACGGGGTCGGTTTCGACA
TGGCCTATGTGGGCAAACTGTTCAAGCCCTTCGAGCGGCTCCACGGCCCCGATGAGTTCCCCGGCACCGGGGTGGGGCTC
GCCATCGTTCACCGGGTCATGGAACGCCACGACGGCCGCGTCTGGCTCGAAAGCACGCCGGGGGCCGGAACCACCTGTTA
CTTCACTCTGCCTTCCTGCTCGACGTCGACCACGAAAACAACATCTTTTTGA

Upstream 100 bases:

>100_bases
GCCCCAAGCGGAAACGCCGGAGCATCCCGCAAAGACGCGCCTGAAGGTGAACCACTCCGTGGCGCAGCACTTGGGCATCA
CGTTGAAGGAGTAACCCCCC

Downstream 100 bases:

>100_bases
ATAACACGGAGAAACGGAGAGCACGGAGAAGCCCATACCCTGTAGTTTTTGTTCAGCAATCAGAAGACACCATCAACCAA
GTTGATTGTGACTGACATAC

Product: histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MDKNSPCDSSQPANPTPPRDVRGSFRAKLFSATAAGIVILSAVSIVFFLTNQHAILHENLVTEGQLLTRLLAHNARLGLF
AANRDQLADLADGVIRTPDVLEVTIVDRDGRTLARAARQSVSDGGSSAALTQEFSEPVFALQGKGNDDDLYFSPAQQPPQ
AGQRLGTVRVVMDEEKVHAHVRRLTATAVIGALAFLAVGMGLVYLIIRGITRPLTHLSDEVRAIERGETNVLLPVESEDE
IGELTASYNRMVNALRQRREERDEAERQLRELNARLEDKVIDRTAQLEAVNRELESFSYSAAHDLRAPLLRLNGLCKALK
EDCGERLDEEARAYIRRIATVGRQMERVISTMSTLFNVQRRGMTCREMDLGAMVRAIVATLRQADPLREVALTVGPEVTA
HGDTELIWTALENMVGNAWKFTSRTPDARIEFGSIERDGEKVFLLKDNGVGFDMAYVGKLFKPFERLHGPDEFPGTGVGL
AIVHRVMERHDGRVWLESTPGAGTTCYFTLPSCSTSTTKTTSF

Sequences:

>Translated_523_residues
MDKNSPCDSSQPANPTPPRDVRGSFRAKLFSATAAGIVILSAVSIVFFLTNQHAILHENLVTEGQLLTRLLAHNARLGLF
AANRDQLADLADGVIRTPDVLEVTIVDRDGRTLARAARQSVSDGGSSAALTQEFSEPVFALQGKGNDDDLYFSPAQQPPQ
AGQRLGTVRVVMDEEKVHAHVRRLTATAVIGALAFLAVGMGLVYLIIRGITRPLTHLSDEVRAIERGETNVLLPVESEDE
IGELTASYNRMVNALRQRREERDEAERQLRELNARLEDKVIDRTAQLEAVNRELESFSYSAAHDLRAPLLRLNGLCKALK
EDCGERLDEEARAYIRRIATVGRQMERVISTMSTLFNVQRRGMTCREMDLGAMVRAIVATLRQADPLREVALTVGPEVTA
HGDTELIWTALENMVGNAWKFTSRTPDARIEFGSIERDGEKVFLLKDNGVGFDMAYVGKLFKPFERLHGPDEFPGTGVGL
AIVHRVMERHDGRVWLESTPGAGTTCYFTLPSCSTSTTKTTSF
>Mature_523_residues
MDKNSPCDSSQPANPTPPRDVRGSFRAKLFSATAAGIVILSAVSIVFFLTNQHAILHENLVTEGQLLTRLLAHNARLGLF
AANRDQLADLADGVIRTPDVLEVTIVDRDGRTLARAARQSVSDGGSSAALTQEFSEPVFALQGKGNDDDLYFSPAQQPPQ
AGQRLGTVRVVMDEEKVHAHVRRLTATAVIGALAFLAVGMGLVYLIIRGITRPLTHLSDEVRAIERGETNVLLPVESEDE
IGELTASYNRMVNALRQRREERDEAERQLRELNARLEDKVIDRTAQLEAVNRELESFSYSAAHDLRAPLLRLNGLCKALK
EDCGERLDEEARAYIRRIATVGRQMERVISTMSTLFNVQRRGMTCREMDLGAMVRAIVATLRQADPLREVALTVGPEVTA
HGDTELIWTALENMVGNAWKFTSRTPDARIEFGSIERDGEKVFLLKDNGVGFDMAYVGKLFKPFERLHGPDEFPGTGVGL
AIVHRVMERHDGRVWLESTPGAGTTCYFTLPSCSTSTTKTTSF

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=411, Percent_Identity=24.0875912408759, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=536, Percent_Identity=21.0820895522388, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=25.8064516129032, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=332, Percent_Identity=25.6024096385542, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=350, Percent_Identity=24, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57723; Mature: 57723

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNSPCDSSQPANPTPPRDVRGSFRAKLFSATAAGIVILSAVSIVFFLTNQHAILHENL
CCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VTEGQLLTRLLAHNARLGLFAANRDQLADLADGVIRTPDVLEVTIVDRDGRTLARAARQS
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
VSDGGSSAALTQEFSEPVFALQGKGNDDDLYFSPAQQPPQAGQRLGTVRVVMDEEKVHAH
HCCCCCCHHHHHHHCCCEEEEECCCCCCCEEECCCCCCHHHHHHCCEEEEEECHHHHHHH
VRRLTATAVIGALAFLAVGMGLVYLIIRGITRPLTHLSDEVRAIERGETNVLLPVESEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
IGELTASYNRMVNALRQRREERDEAERQLRELNARLEDKVIDRTAQLEAVNRELESFSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AAHDLRAPLLRLNGLCKALKEDCGERLDEEARAYIRRIATVGRQMERVISTMSTLFNVQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMTCREMDLGAMVRAIVATLRQADPLREVALTVGPEVTAHGDTELIWTALENMVGNAWK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCEE
FTSRTPDARIEFGSIERDGEKVFLLKDNGVGFDMAYVGKLFKPFERLHGPDEFPGTGVGL
ECCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHH
AIVHRVMERHDGRVWLESTPGAGTTCYFTLPSCSTSTTKTTSF
HHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDKNSPCDSSQPANPTPPRDVRGSFRAKLFSATAAGIVILSAVSIVFFLTNQHAILHENL
CCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VTEGQLLTRLLAHNARLGLFAANRDQLADLADGVIRTPDVLEVTIVDRDGRTLARAARQS
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
VSDGGSSAALTQEFSEPVFALQGKGNDDDLYFSPAQQPPQAGQRLGTVRVVMDEEKVHAH
HCCCCCCHHHHHHHCCCEEEEECCCCCCCEEECCCCCCHHHHHHCCEEEEEECHHHHHHH
VRRLTATAVIGALAFLAVGMGLVYLIIRGITRPLTHLSDEVRAIERGETNVLLPVESEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
IGELTASYNRMVNALRQRREERDEAERQLRELNARLEDKVIDRTAQLEAVNRELESFSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AAHDLRAPLLRLNGLCKALKEDCGERLDEEARAYIRRIATVGRQMERVISTMSTLFNVQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMTCREMDLGAMVRAIVATLRQADPLREVALTVGPEVTAHGDTELIWTALENMVGNAWK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCEE
FTSRTPDARIEFGSIERDGEKVFLLKDNGVGFDMAYVGKLFKPFERLHGPDEFPGTGVGL
ECCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHH
AIVHRVMERHDGRVWLESTPGAGTTCYFTLPSCSTSTTKTTSF
HHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]